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Did you mean emodin acid (894 results)?
Inhibition of cell-intrinsic NF-kappaB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus.
Abdellatef AA, Fathy M, Mohammed AEI, Bakr MSA, Ahmed AH, Abbass HS, El-Desoky AH, Morita H, Nikaido T, Hayakawa Y. Abdellatef AA, et al. J Nat Med. 2021 Sep;75(4):840-853. doi: 10.1007/s11418-021-01526-w. Epub 2021 May 14. J Nat Med. 2021. PMID: 33988779
In this study, five anthraquinone-type analogs were isolated from the methanol extract of A. microcarpus leaves and identified as, emodin, rhein, physcion, aloe-emodin, and emodic acid. Among them, aloe-emodin and emodic-acid strongly inhibited the pro …
In this study, five anthraquinone-type analogs were isolated from the methanol extract of A. microcarpus leaves and identified as, emodin, r …
Generation of free radicals by emodic acid and its [D-Lys6]GnRH-conjugate.
Rahimipour S, Bilkis I, Péron V, Gescheidt G, Barbosa F, Mazur Y, Koch Y, Weiner L, Fridkin M. Rahimipour S, et al. Photochem Photobiol. 2001 Aug;74(2):226-36. doi: 10.1562/0031-8655(2001)074<0226:gofrbe>2.0.co;2. Photochem Photobiol. 2001. PMID: 11547560
In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Em …
In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing ho …
A new anthraquinone derivative from the marine fish-derived fungus Alternaria sp. X112.
Xu X, Li G, Fu R, Lou H, Peng X. Xu X, et al. Nat Prod Res. 2023 Sep 21:1-6. doi: 10.1080/14786419.2023.2258540. Online ahead of print. Nat Prod Res. 2023. PMID: 37732591
A new anthraquinone, altermodinacid A (1), and five known derivatives, pachybasic acid (2), emodic acid (3), emodin (4), phomarin (5), and 1,7-dihydroxy-3-methylanthracene-9,10-dione (6), were discovered from a halotolerant fungus Alternaria sp. ...
A new anthraquinone, altermodinacid A (1), and five known derivatives, pachybasic acid (2), emodic acid (3), emodin (4) …
Metabolism of [14C]emodin in the rat.
Bachmann M, Schlatter C. Bachmann M, et al. Xenobiotica. 1981 Mar;11(3):217-25. doi: 10.3109/00498258109045294. Xenobiotica. 1981. PMID: 7293218
Metabolites found in pooled urine (0-72 h) were mostly free anthraquinones (emodin and emodic acid, 16% dose); 3% was conjugated and 3% was non-extractable radioactivity. 4. ...
Metabolites found in pooled urine (0-72 h) were mostly free anthraquinones (emodin and emodic acid, 16% dose); 3% was conjugat …
Biofilm inhibition mechanism from extract of Hymenocallis littoralis leaves.
Nadaf NH, Parulekar RS, Patil RS, Gade TK, Momin AA, Waghmare SR, Dhanavade MJ, Arvindekar AU, Sonawane KD. Nadaf NH, et al. J Ethnopharmacol. 2018 Aug 10;222:121-132. doi: 10.1016/j.jep.2018.04.031. Epub 2018 Apr 24. J Ethnopharmacol. 2018. PMID: 29698774
The various phytochemicals such as Apigenin 7-(4'', 6'' diacetylalloside)-4'- alloside, Catechin 7-O- apiofuranoside, Emodic acid, Epicatechin 3-O- beta-D-glucopyranoside, 4 - Methylesculetin, Methylisoeugenol, Quercetin 5,7,3',4'-tetramethyl ether 3-rutinoside, 4 - …
The various phytochemicals such as Apigenin 7-(4'', 6'' diacetylalloside)-4'- alloside, Catechin 7-O- apiofuranoside, Emodic acid …
Endophytic Microbes from Medicinal Plants in Fenghuang Mountain as a Source of Antibiotics.
Yang A, Hong Y, Zhou F, Zhang L, Zhu Y, Wang C, Hu Y, Yu L, Chen L, Wang X. Yang A, et al. Molecules. 2023 Aug 28;28(17):6301. doi: 10.3390/molecules28176301. Molecules. 2023. PMID: 37687129 Free PMC article.
According to antibacterial data, S. aureus or B. subtilis were inhibited to varying degrees by sorrentanone (3), emodic acid (8), GKK1032 B (10), linoleic acid (14), toyocamycin (17) and quinomycin A (21). ...
According to antibacterial data, S. aureus or B. subtilis were inhibited to varying degrees by sorrentanone (3), emodic acid ( …
Differential inhibition of matrix metalloproteinases-2, -9, and -13 activities by selected anthraquinones.
Wierzchacz C, Su E, Kolander J, Gebhardt R. Wierzchacz C, et al. Planta Med. 2009 Mar;75(4):327-9. doi: 10.1055/s-0028-1112205. Epub 2009 Jan 16. Planta Med. 2009. PMID: 19152226
The IC50 values determined by measuring the activities of human recombinant catalytic domains of these enzymes varied in the micromolar range. Emodin and emodic acid most potently inhibited MMP-9 with IC50 values of 15 and 10 microM, respectively. With MMP-13, em …
The IC50 values determined by measuring the activities of human recombinant catalytic domains of these enzymes varied in the micromolar rang …
In silico identification of natural product inhibitors of JAK2.
Zhong HJ, Lin S, Tam IL, Lu L, Chan DS, Ma DL, Leung CH. Zhong HJ, et al. Methods. 2015 Jan;71:21-5. doi: 10.1016/j.ymeth.2014.07.003. Epub 2014 Jul 16. Methods. 2015. PMID: 25038528
Emodic acid (1) and 6-chloroemodic acid (2) have been identified from a natural product database as useful scaffolds for the future development of novel JAK2 inhibitors using structure-based high-throughput virtual screening. ...
Emodic acid (1) and 6-chloroemodic acid (2) have been identified from a natural product database as useful scaffolds fo …
Design, synthesis, and evaluation of a long-acting, potent analogue of gonadotropin-releasing hormone.
Rahimipour S, Ben-Aroya N, Fridkin M, Koch Y. Rahimipour S, et al. J Med Chem. 2001 Oct 25;44(22):3645-52. doi: 10.1021/jm010112g. J Med Chem. 2001. PMID: 11606129
The prolonged activity of [D-Lys(6)(Emo)]GnRH may be attributed to its emodic acid moiety, which enhances the binding affinity of the analogue to human serum albumin. Indeed, we found that emodic acid binds to human serum albumin almost completely at t …
The prolonged activity of [D-Lys(6)(Emo)]GnRH may be attributed to its emodic acid moiety, which enhances the binding affinity …
17 results