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Year Number of Results
1921 1
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1948 132
1949 95
1950 169
1951 361
1952 424
1953 285
1954 249
1955 238
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1957 278
1958 276
1959 225
1960 227
1961 272
1962 312
1963 757
1964 1248
1965 1386
1966 1671
1967 1822
1968 2166
1969 2421
1970 2468
1971 2638
1972 2619
1973 2876
1974 2964
1975 3176
1976 3506
1977 3295
1978 3639
1979 4084
1980 4178
1981 4341
1982 4850
1983 6163
1984 7417
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1986 7263
1987 7209
1988 7189
1989 7843
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1993 9075
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1997 9645
1998 9381
1999 9765
2000 10334
2001 10710
2002 11490
2003 12435
2004 13624
2005 15750
2006 17152
2007 18254
2008 19318
2009 20310
2010 22645
2011 24309
2012 25635
2013 26583
2014 27553
2015 28227
2016 28664
2017 29069
2018 29793
2019 30645
2020 30027
2021 26693
2022 19402
2023 17630
2024 6077

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656,064 results

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Page 1
Artificial Intelligence for Drug Toxicity and Safety.
Basile AO, Yahi A, Tatonetti NP. Basile AO, et al. Trends Pharmacol Sci. 2019 Sep;40(9):624-635. doi: 10.1016/j.tips.2019.07.005. Epub 2019 Aug 2. Trends Pharmacol Sci. 2019. PMID: 31383376 Free PMC article. Review.
Interventional pharmacology is one of medicine's most potent weapons against disease. These drugs, however, can result in damaging side effects and must be closely monitored. Pharmacovigilance is the field of science that monitors, detects, and prevents adverse …
Interventional pharmacology is one of medicine's most potent weapons against disease. These drugs, however, can result in damaging side …
Adverse drug reactions.
Montané E, Santesmases J. Montané E, et al. Med Clin (Barc). 2020 Mar 13;154(5):178-184. doi: 10.1016/j.medcli.2019.08.007. Epub 2019 Nov 23. Med Clin (Barc). 2020. PMID: 31771857 Review. English, Spanish.
An adverse drug reaction (ADR) is defined as a response to a medicinal product which is noxious and unintended. ...The pharmacovigilance systems allow the identification and prevention of the risks associated with use of a drug, especially of recently markete …
An adverse drug reaction (ADR) is defined as a response to a medicinal product which is noxious and unintended. ...The pharmac …
Adverse drug reactions: definitions, diagnosis, and management.
Edwards IR, Aronson JK. Edwards IR, et al. Lancet. 2000 Oct 7;356(9237):1255-9. doi: 10.1016/S0140-6736(00)02799-9. Lancet. 2000. PMID: 11072960
Timing, the pattern of illness, the results of investigations, and rechallenge can help attribute causality to a suspected adverse drug reaction. Management includes withdrawal of the drug if possible and specific treatment of its effects. Suspected …
Timing, the pattern of illness, the results of investigations, and rechallenge can help attribute causality to a suspected adverse …
The endoplasmic reticulum participated in drug metabolic toxicity.
Huang Q, Chen Y, Zhang Z, Xue Z, Hua Z, Luo X, Li Y, Lu C, Lu A, Liu Y. Huang Q, et al. Cell Biol Toxicol. 2022 Dec;38(6):945-961. doi: 10.1007/s10565-021-09689-8. Epub 2022 Jan 18. Cell Biol Toxicol. 2022. PMID: 35040016 Review.
Covalent binding of reactive metabolites formed by drug metabolic activation with biological macromolecules is considered to be an important mechanism of drug metabolic toxicity. Recent studies indicate that the endoplasmic reticulum (ER) could play an import …
Covalent binding of reactive metabolites formed by drug metabolic activation with biological macromolecules is considered to be an im …
Drug allergy: an updated practice parameter.
Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Joint Task Force on Practice Parameters, et al. Ann Allergy Asthma Immunol. 2010 Oct;105(4):259-273. doi: 10.1016/j.anai.2010.08.002. Ann Allergy Asthma Immunol. 2010. PMID: 20934625
Adverse drug reactions (ADRs) result in major health problems in the United States in both the inpatient and outpatient setting. ...Unpredictable are generally dose independent, are unrelated to the pharmacologic actions of the drug, and occur only in …
Adverse drug reactions (ADRs) result in major health problems in the United States in both the inpatient and outpatient …
The influence of gut microbiota on drug metabolism and toxicity.
Li H, He J, Jia W. Li H, et al. Expert Opin Drug Metab Toxicol. 2016;12(1):31-40. doi: 10.1517/17425255.2016.1121234. Epub 2015 Dec 10. Expert Opin Drug Metab Toxicol. 2016. PMID: 26569070 Free PMC article. Review.
INTRODUCTION: Gut microbiota plays critical roles in drug metabolism. The variation of gut microbiota contributes to the interindividual differences toward drug therapy including drug-induced toxicity and efficacy. Accordingly, the investigation and el …
INTRODUCTION: Gut microbiota plays critical roles in drug metabolism. The variation of gut microbiota contributes to the interindivid …
Drug toxicity in the neonate.
McIntyre J, Choonara I. McIntyre J, et al. Biol Neonate. 2004;86(4):218-21. doi: 10.1159/000079656. Epub 2004 Jul 8. Biol Neonate. 2004. PMID: 15249753 Review.
The incidence of adverse drug reactions in neonates is thought to be at least 10%. The physiology of the newborn infant is different to that of both paediatric patients and adults. This therefore predisposes to certain types of drug toxicity, wh …
The incidence of adverse drug reactions in neonates is thought to be at least 10%. The physiology of the newborn infant …
Applications of Machine Learning Methods in Drug Toxicity Prediction.
Zhang L, Zhang H, Ai H, Hu H, Li S, Zhao J, Liu H. Zhang L, et al. Curr Top Med Chem. 2018;18(12):987-997. doi: 10.2174/1568026618666180727152557. Curr Top Med Chem. 2018. PMID: 30051792 Review.
Computational methods developed for drug toxicity prediction can compensate for the shortcomings of traditional methods and have been considered useful in the early stages of drug development. Numerous drug toxicity prediction models have been d …
Computational methods developed for drug toxicity prediction can compensate for the shortcomings of traditional methods and ha …
Drug toxicity.
DOMINIKOVICH EG. DOMINIKOVICH EG. N Z Med J. 1962 Sep;61:467-9. N Z Med J. 1962. PMID: 14028537 No abstract available.
Polypharmacy Management in Older Patients.
Hoel RW, Giddings Connolly RM, Takahashi PY. Hoel RW, et al. Mayo Clin Proc. 2021 Jan;96(1):242-256. doi: 10.1016/j.mayocp.2020.06.012. Mayo Clin Proc. 2021. PMID: 33413822 Review.
This imprecise label usually describes the accumulation of 5, and often more, medications. Polypharmacy in advancing age frequently results in drug therapy problems related to interactions, drug toxicity, falls with injury, delirium, and nonadherence. ...To r …
This imprecise label usually describes the accumulation of 5, and often more, medications. Polypharmacy in advancing age frequently results …
656,064 results
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