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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1966 1
1968 1
1975 2
1977 1
1978 2
1979 7
1980 2
1981 1
1982 4
1983 5
1984 5
1985 1
1986 7
1987 6
1988 11
1989 12
1990 25
1991 6
1992 6
1993 21
1994 19
1995 22
1996 33
1997 40
1998 47
1999 58
2000 62
2001 73
2002 80
2003 111
2004 120
2005 140
2006 144
2007 175
2008 159
2009 210
2010 223
2011 294
2012 306
2013 381
2014 388
2015 464
2016 513
2017 526
2018 511
2019 605
2020 670
2021 727
2022 644
2023 604
2024 221

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7,674 results

Results by year

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Page 1
Anatomical and physiological alterations of pregnancy.
Kazma JM, van den Anker J, Allegaert K, Dallmann A, Ahmadzia HK. Kazma JM, et al. J Pharmacokinet Pharmacodyn. 2020 Aug;47(4):271-285. doi: 10.1007/s10928-020-09677-1. Epub 2020 Feb 6. J Pharmacokinet Pharmacodyn. 2020. PMID: 32026239 Free PMC article. Review.
Furthermore, these physiological alterations can affect the pharmacokinetics and pharmacodynamics of drugs. Drug safety in lactation is only supported by limited evidence. ...Unfortunately, pregnant women are only rarely included in clinical drug trial …
Furthermore, these physiological alterations can affect the pharmacokinetics and pharmacodynamics of drugs. Drug safety …
Membrane transporters in drug development.
International Transporter Consortium; Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. International Transporter Consortium, et al. Nat Rev Drug Discov. 2010 Mar;9(3):215-36. doi: 10.1038/nrd3028. Nat Rev Drug Discov. 2010. PMID: 20190787 Free PMC article. Review.
Membrane transporters can be major determinants of the pharmacokinetic, safety and efficacy profiles of drugs. This presents several key questions for drug development, including which transporters are clinically important in drug absorption and dispos …
Membrane transporters can be major determinants of the pharmacokinetic, safety and efficacy profiles of drugs. This presents s …
Drugs Associated With Ischemic Stroke: A Review for Clinicians.
Marto JP, Strambo D, Livio F, Michel P. Marto JP, et al. Stroke. 2021 Oct;52(10):e646-e659. doi: 10.1161/STROKEAHA.120.033272. Epub 2021 Aug 18. Stroke. 2021. PMID: 34404236 Review.
We created an initial list of frequently used drugs to search Pubmed/MEDLINE from 1966 to 2020 and reviewed phase III and IV data, case series, and drug authorities' safety warnings to assess a potential association with IS. ...The summarized information may …
We created an initial list of frequently used drugs to search Pubmed/MEDLINE from 1966 to 2020 and reviewed phase III and IV data, ca …
Use of Therapeutics in Pregnancy and Lactation.
Eyal S. Eyal S. Pharm Res. 2018 Mar 23;35(5):107. doi: 10.1007/s11095-018-2390-9. Pharm Res. 2018. PMID: 29572667
This theme issue of Pharmaceutical Research is dedicated to drug research and therapy in pregnant and breastfeeding woman. Enthusiasm for studying drug safety and toxicity in these patients (and in their children) has risen over the past decade. ...
This theme issue of Pharmaceutical Research is dedicated to drug research and therapy in pregnant and breastfeeding woman. Enthusiasm …
Drugs and Diseases Interacting with Cigarette Smoking in US Prescription Drug Labelling.
Li H, Shi Q. Li H, et al. Clin Pharmacokinet. 2015 May;54(5):493-501. doi: 10.1007/s40262-015-0246-6. Clin Pharmacokinet. 2015. PMID: 25701380 Review.
The resultant records were refined to include only human prescription drug labelling, for manual examination. For 188 single-active-ingredient drugs and 36 multiple-active-ingredient drugs, the labelling was found to contain smoking-related information …
The resultant records were refined to include only human prescription drug labelling, for manual examination. For 188 single-a …
FDA drug safety communications: a narrative review and clinical considerations for older adults.
Marcum ZA, Vande Griend JP, Linnebur SA. Marcum ZA, et al. Am J Geriatr Pharmacother. 2012 Aug;10(4):264-71. doi: 10.1016/j.amjopharm.2012.05.002. Epub 2012 Jun 8. Am J Geriatr Pharmacother. 2012. PMID: 22683398 Free PMC article. Review.
BACKGROUND: The US Food and Drug Administration (FDA) has new regulatory authorities intended to enhance drug safety monitoring in the postmarketing period. ...RESULTS: FDA drug safety communications for 4 drugs were chosen because of the …
BACKGROUND: The US Food and Drug Administration (FDA) has new regulatory authorities intended to enhance drug safety mo …
Nonbioequivalent prescription drug interchangeability, concerns on patient safety and drug market dynamics in Brazil.
Paumgartten FJR, Oliveira ACAX. Paumgartten FJR, et al. Cien Saude Colet. 2017 Aug;22(8):2549-2558. doi: 10.1590/1413-81232017228.04352017. Cien Saude Colet. 2017. PMID: 28793071 Free article.
Starting in 2003, Brazilian Sanitary Surveillance Agency (Anvisa) has required data on relative bioavailability tests (with REF) to approve (or renew registration of) S drugs. In 2014, Anvisa extended interchangeability notion to similar drugs with a "comparable" bi …
Starting in 2003, Brazilian Sanitary Surveillance Agency (Anvisa) has required data on relative bioavailability tests (with REF) to approve …
Analysis of Issues and Future Trends Impacting Drug Safety in South Korea.
Kim MG, Huh S, Han N, Kim JH, Kim K, Lee E, Kim IW, Oh JM. Kim MG, et al. Int J Environ Res Public Health. 2019 Sep 12;16(18):3368. doi: 10.3390/ijerph16183368. Int J Environ Res Public Health. 2019. PMID: 31547245 Free PMC article.
New drug safety issues are emerging that are beyond the existing medication safety management system. To pre-empt these problems, forecasting future drug safety trends and issues is a necessity. The objective of this study was to identify issues …
New drug safety issues are emerging that are beyond the existing medication safety management system. To pre-empt these …
Prescription drug overdoses: a review.
Paulozzi LJ. Paulozzi LJ. J Safety Res. 2012 Sep;43(4):283-9. doi: 10.1016/j.jsr.2012.08.009. Epub 2012 Aug 25. J Safety Res. 2012. PMID: 23127678 Review.
PROBLEM: Overdoses involving prescription drugs in the United States have reached epidemic proportions over the past 20 years. ...Environmental factors include rural residence and high community prescribing rates. DISCUSSION: The epidemiology of prescription …
PROBLEM: Overdoses involving prescription drugs in the United States have reached epidemic proportions over the past 20 years. …
7,674 results