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Page 1
Pneumonia and respiratory infection in Down syndrome: A 10-year cohort analysis of inpatient and outpatient encounters across the lifespan.
Blake JM, Estrada Gomez D, Skotko BG, Torres A, Santoro SL. Blake JM, et al. Am J Med Genet A. 2021 Oct;185(10):2878-2887. doi: 10.1002/ajmg.a.62355. Epub 2021 May 31. Am J Med Genet A. 2021. PMID: 34056836
Respiratory illnesses are a significant contributor of morbidity and mortality among persons with Down syndrome (DS). Reviews have described respiratory illnesses of DS in childhood, but few have looked across the lifespan. ...Patients were seen predominately in out …
Respiratory illnesses are a significant contributor of morbidity and mortality among persons with Down syndrome (DS). Reviews …
Down Syndrome and Postoperative Complications in Children Undergoing Intestinal Operations.
Cairo SB, Zeinali LI, Berkelhamer SK, Harmon CM, Rao SO, Rothstein DH. Cairo SB, et al. J Pediatr Surg. 2019 Sep;54(9):1832-1837. doi: 10.1016/j.jpedsurg.2018.11.013. Epub 2018 Dec 13. J Pediatr Surg. 2019. PMID: 30611525
OBJECTIVE: This paper intends to evaluate the association between Down Syndrome (DS) and postoperative medical and surgical complications and inpatient postoperative mortality in pediatric patients undergoing intestinal operations. ...Similar to patients unde …
OBJECTIVE: This paper intends to evaluate the association between Down Syndrome (DS) and postoperative medical and surgical co …
Greater risk of hospitalization in children with Down syndrome and OSA at higher elevation.
Jensen KM, Sevick CJ, Seewald LAS, Halbower AC, Davis MM, McCabe ERB, Kempe A, Abman SH. Jensen KM, et al. Chest. 2015 May;147(5):1344-1351. doi: 10.1378/chest.14-1883. Chest. 2015. PMID: 25654790
BACKGROUND: Children with Down syndrome (DS) are at high risk for OSA. Increasing elevation is known to exacerbate underlying respiratory disorders and worsen sleep quality in people without DS, but whether altitude modulates the severity of OSA in DS is uncertain. …
BACKGROUND: Children with Down syndrome (DS) are at high risk for OSA. Increasing elevation is known to exacerbate underlying …
Disability, Hospital Care, and Cost: Utilization of Emergency and Inpatient Care by a Cohort of Children with Intellectual and Developmental Disabilities.
Lindgren S, Lauer E, Momany E, Cope T, Royer J, Cogan L, McDermott S, Armour BS. Lindgren S, et al. J Pediatr. 2021 Feb;229:259-266. doi: 10.1016/j.jpeds.2020.08.084. Epub 2020 Sep 2. J Pediatr. 2021. PMID: 32890584 Free PMC article.
STUDY DESIGN: Medicaid administrative claims from 4 states (Iowa, Massachusetts, New York, and South Carolina) from years 2008-2013 were analyzed, including 108 789 children (75 417 male; 33 372 female) under age 18 years with intellectual and developmental disabilities. Diagnose …
STUDY DESIGN: Medicaid administrative claims from 4 states (Iowa, Massachusetts, New York, and South Carolina) from years 2008-2013 were ana …
Specialized interferon action in COVID-19.
Galbraith MD, Kinning KT, Sullivan KD, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter R, Jordan KR, Russell S, Dzieciatkowska M, Reisz JA, Gamboni F, Cendali F, Ghosh T, Guo K, Wilson CC, Santiago ML, Monte AA, Bennett TD, Hansen KC, Hsieh EWY, D'Alessandro A, Espinosa JM. Galbraith MD, et al. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2116730119. doi: 10.1073/pnas.2116730119. Proc Natl Acad Sci U S A. 2022. PMID: 35217532 Free PMC article.
Down Syndrome Increases the Risk of Short-Term Complications After Total Hip Arthroplasty.
Boylan MR, Kapadia BH, Issa K, Perfetti DC, Maheshwari AV, Mont MA. Boylan MR, et al. J Arthroplasty. 2016 Feb;31(2):368-72. doi: 10.1016/j.arth.2015.09.031. Epub 2015 Sep 28. J Arthroplasty. 2016. PMID: 26482683
METHODS: Using Nationwide Inpatient Sample (NIS) data from 1998 to 2010, we compared the short-term adverse outcomes of THA among 241 patients with Down syndrome and a matched 723-patient cohort. ...Down syndrome patients had significantly highe …
METHODS: Using Nationwide Inpatient Sample (NIS) data from 1998 to 2010, we compared the short-term adverse outcomes of THA among 241 …
Hospitalisation of adults with Down syndrome: lesson from a 10-year experience from a community hospital.
Chenbhanich J, Wu A, Phupitakphol T, Atsawarungruangkit A, Treadwell T. Chenbhanich J, et al. J Intellect Disabil Res. 2019 Mar;63(3):266-276. doi: 10.1111/jir.12572. Epub 2018 Nov 28. J Intellect Disabil Res. 2019. PMID: 30484927

BACKGROUND: Life expectancy of individuals with Down syndrome (DS) has improved significantly over the past decades. ...Male patients were hospitalised longer than female patients (mean 5.0 vs. 2.8 days; P < 0.05), and patients who lived at home were admitted at

BACKGROUND: Life expectancy of individuals with Down syndrome (DS) has improved significantly over the past decades. ...Male p …
The development of inpatient cost and nursing service weights in a tertiary hospital in Malaysia.
Hassan NH, Aljunid SM, Nur AM. Hassan NH, et al. BMC Health Serv Res. 2020 Oct 14;20(1):945. doi: 10.1186/s12913-020-05776-4. BMC Health Serv Res. 2020. PMID: 33054861 Free PMC article.
Finally, the highest nursing cost and service weights for paediatric were from P-8-08-II (neonate birthweight > 2499 g with respiratory distress syndrome congenital pneumonia - moderate, RM1,300; 1.0582). Multiple linear regression analysis showed that nursing ho …
Finally, the highest nursing cost and service weights for paediatric were from P-8-08-II (neonate birthweight > 2499 g with respiratory d …
Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning.
Patel MA, Knauer MJ, Nicholson M, Daley M, Van Nynatten LR, Cepinskas G, Fraser DD. Patel MA, et al. Mol Med. 2023 Feb 21;29(1):26. doi: 10.1186/s10020-023-00610-z. Mol Med. 2023. PMID: 36809921 Free PMC article.
METHODS: A case-control study comparing the expression of 2925 unique blood proteins in Long-COVID outpatients versus COVID-19 inpatients and healthy control subjects. Targeted proteomics was accomplished with proximity extension assays, and machine learning was used to id …
METHODS: A case-control study comparing the expression of 2925 unique blood proteins in Long-COVID outpatients versus COVID-19 inpatients
Health care utilisation among older people with Down syndrome compared to specific medical guidelines for health surveillance: a Swedish national register study.
Ahlström G, Axmon A, Sandberg M, Flygare Wallén E. Ahlström G, et al. BMC Health Serv Res. 2020 Oct 15;20(1):949. doi: 10.1186/s12913-020-05800-7. BMC Health Serv Res. 2020. PMID: 33059705 Free PMC article.
BACKGROUND: Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to the guidelines is lacking. ...RESULTS: A total of 3854 inpatient and outpatient specialist health care visits …
BACKGROUND: Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but kn …
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