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2020 2
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Up-regulation of the D1 dopamine receptor-interacting protein, calcyon, in patients with schizophrenia.
Koh PO, Bergson C, Undie AS, Goldman-Rakic PS, Lidow MS. Koh PO, et al. Arch Gen Psychiatry. 2003 Mar;60(3):311-9. doi: 10.1001/archpsyc.60.3.311. Arch Gen Psychiatry. 2003. PMID: 12622665
The present study focuses on a recently recognized group of dopamine receptor-interacting proteins as possible novel sites of dysfunction in schizophrenia. Specifically, we examined whether the D1 dopamine receptor-interacting protein calcyon an …
The present study focuses on a recently recognized group of dopamine receptor-interacting proteins as possible novel sites of …
Up-regulation of the Trace Amine Receptor, TAAR-1, in the Prefrontal Cortex of Individuals Affected by Schizophrenia.
Imbriglio T, Alborghetti M, Bruno V, Battaglia G, Nicoletti F, Cannella M. Imbriglio T, et al. Schizophr Bull. 2024 Mar 7;50(2):374-381. doi: 10.1093/schbul/sbad148. Schizophr Bull. 2024. PMID: 37897399
We hypothesized that schizophrenia (SCZ) causes adaptive changes in TAAR1 expression in the prefrontal cortex. ...In the SCZ group, levels showed an inverse correlation with the duration of antipsychotic treatment and were higher in individuals treated with s …
We hypothesized that schizophrenia (SCZ) causes adaptive changes in TAAR1 expression in the prefrontal cortex. ...In th …
Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology.
Fuxe K, Marcellino D, Rivera A, Diaz-Cabiale Z, Filip M, Gago B, Roberts DC, Langel U, Genedani S, Ferraro L, de la Calle A, Narvaez J, Tanganelli S, Woods A, Agnati LF. Fuxe K, et al. Brain Res Rev. 2008 Aug;58(2):415-52. doi: 10.1016/j.brainresrev.2007.11.007. Epub 2008 Jan 28. Brain Res Rev. 2008. PMID: 18222544 Review.
Future therapies for diseases associated with altered dopaminergic signaling, including Parkinson's disease, schizophrenia and drug addiction or drug dependence may substantially build on the existence of intramembrane receptor-receptor interactions within …
Future therapies for diseases associated with altered dopaminergic signaling, including Parkinson's disease, schizophrenia and drug a …
Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients.
Koh PO, Undie AS, Kabbani N, Levenson R, Goldman-Rakic PS, Lidow MS. Koh PO, et al. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):313-7. doi: 10.1073/pnas.232693499. Epub 2002 Dec 20. Proc Natl Acad Sci U S A. 2003. PMID: 12496348 Free PMC article.
The present study focuses on a recently recognized group of dopamine receptor-interacting proteins as possible novel sites of dysfunction in schizophrenic and bipolar patients. We demonstrate that the dorsolateral prefrontal cortex in schizophrenia
The present study focuses on a recently recognized group of dopamine receptor-interacting proteins as possible novel sites of …
Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia.
Grace AA. Grace AA. Neuroscience. 1991;41(1):1-24. doi: 10.1016/0306-4522(91)90196-u. Neuroscience. 1991. PMID: 1676137 Review.
This hypothesis is based on the regulation of dopamine release into subcortical regions occurring via two independent mechanisms: (1) transient or phasic dopamine release caused by dopamine neuron firing, and (2) sustained, "background" tonic dopami
This hypothesis is based on the regulation of dopamine release into subcortical regions occurring via two independent mechanis …
Similarities in the behavior and molecular deficits in the frontal cortex between the neurotensin receptor subtype 1 knockout mice and chronic phencyclidine-treated mice: relevance to schizophrenia.
Li Z, Boules M, Williams K, Gordillo A, Li S, Richelson E. Li Z, et al. Neurobiol Dis. 2010 Nov;40(2):467-77. doi: 10.1016/j.nbd.2010.07.011. Epub 2010 Jul 24. Neurobiol Dis. 2010. PMID: 20659557 Free PMC article.
Our results showed many similarities between untreated NTS1(-/-) mice and WT mice chronically treated with PCP (as compared with untreated WT mice): 1) lower PCP-induced locomotor activity; 2) similar avolition-like behavior in forced-swim test and tail suspension test; 3) lower …
Our results showed many similarities between untreated NTS1(-/-) mice and WT mice chronically treated with PCP (as compared with untreated W …
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment.
Stark T, Di Bartolomeo M, Di Marco R, Drazanova E, Platania CBM, Iannotti FA, Ruda-Kucerova J, D'Addario C, Kratka L, Pekarik V, Piscitelli F, Babinska Z, Fedotova J, Giurdanella G, Salomone S, Sulcova A, Bucolo C, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V. Stark T, et al. Biochem Pharmacol. 2020 Jul;177:114004. doi: 10.1016/j.bcp.2020.114004. Epub 2020 Apr 28. Biochem Pharmacol. 2020. PMID: 32360362
Here we show that adult rats prenatally treated with MAM at gestational day 17 display significant increase in dopamine D3 receptor (D3) mRNA expression in prefrontal cortex (PFC), hippocampus and nucleus accumbens, accompanied by increased expression …
Here we show that adult rats prenatally treated with MAM at gestational day 17 display significant increase in dopamine D3 recepto
rTMS of the left dorsolateral prefrontal cortex modulates dopamine release in the ipsilateral anterior cingulate cortex and orbitofrontal cortex.
Cho SS, Strafella AP. Cho SS, et al. PLoS One. 2009 Aug 21;4(8):e6725. doi: 10.1371/journal.pone.0006725. PLoS One. 2009. PMID: 19696930 Free PMC article.
BACKGROUND: Brain dopamine is implicated in the regulation of movement, attention, reward and learning and plays an important role in Parkinson's disease, schizophrenia and drug addiction. ...Given the up-growing interest of non-invasive brain stimulation as …
BACKGROUND: Brain dopamine is implicated in the regulation of movement, attention, reward and learning and plays an important …
Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity.
Clarke HF, Cardinal RN, Rygula R, Hong YT, Fryer TD, Sawiak SJ, Ferrari V, Cockcroft G, Aigbirhio FI, Robbins TW, Roberts AC. Clarke HF, et al. J Neurosci. 2014 May 28;34(22):7663-76. doi: 10.1523/JNEUROSCI.0718-14.2014. J Neurosci. 2014. PMID: 24872570 Free PMC article.
Schizophrenia is associated with upregulation of dopamine (DA) release in the caudate nucleus. ...Despite evidence that abnormalities in dopaminergic neurotransmission and prefrontal cortex function co-occur in schizophrenia, the influence of OF
Schizophrenia is associated with upregulation of dopamine (DA) release in the caudate nucleus. ...Despite evidence that abnorm
Recent evidence for dopamine abnormalities in schizophrenia.
Abi-Dargham A. Abi-Dargham A. Eur Psychiatry. 2002 Aug;17 Suppl 4:341s-347s. doi: 10.1016/s0924-9338(03)00075-0. Eur Psychiatry. 2002. PMID: 23573603 Review.
Recent studies have also produced new evidence of dopaminergic disturbance in the cortex. When controls were compared with patients with schizophrenia, we found a significant increase in D1 receptors in patients, but only in the dorsolateral prefrontal
Recent studies have also produced new evidence of dopaminergic disturbance in the cortex. When controls were compared with patients w …
24 results