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A literature review on function and regulation mechanism of DKK4.
Lou X, Meng Y, Hou Y. Lou X, et al. J Cell Mol Med. 2021 Mar;25(6):2786-2794. doi: 10.1111/jcmm.16372. Epub 2021 Feb 14. J Cell Mol Med. 2021. PMID: 33586359 Free PMC article. Review.
Dickkopf-related protein 4 (DKK4) is a member of the dickkopf family and an inhibitor of the Wnt/beta-catenin signalling pathway. ...DKK4 has also been linked to schizophrenia....
Dickkopf-related protein 4 (DKK4) is a member of the dickkopf family and an inhibitor of the Wnt/beta-catenin signalling pathway. ... …
[Association of the schizophrenia susceptible gene DKK4 with brain volume in Chinese populations].
Zhang LH, Li M, Shi XD, Ren H, Su B, Xu Z. Zhang LH, et al. Dongwuxue Yanjiu. 2011 Feb;32(1):62-5. doi: 10.3724/SP.J.1141.2011.01062. Dongwuxue Yanjiu. 2011. PMID: 21341386 Free article. Chinese.
Recently, the DKK4 gene involved in the Wnt signaling was found to be significantly associated with schizophrenia. To test whether DKK4 is associated with neurodevelopment, we genotyped one DKK4 SNP in 961 healthy Chinese individuals and measured their …
Recently, the DKK4 gene involved in the Wnt signaling was found to be significantly associated with schizophrenia. To test whe …
Positional pathway screen of wnt signaling genes in schizophrenia: association with DKK4.
Proitsi P, Li T, Hamilton G, Di Forti M, Collier D, Killick R, Chen R, Sham P, Murray R, Powell J, Lovestone S. Proitsi P, et al. Biol Psychiatry. 2008 Jan 1;63(1):13-6. doi: 10.1016/j.biopsych.2007.03.014. Epub 2007 Jun 5. Biol Psychiatry. 2008. PMID: 17553464

RESULTS: In both sets, Dickkopf 4 (DKK4) was associated with schizophrenia - with an odds ratio of 3.9 (p < .01, CI = 1.3-11.1) in the combined sample. CONCLUSIONS: As DKK family members have previously been found to show altered expression in schizophrenia

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RESULTS: In both sets, Dickkopf 4 (DKK4) was associated with schizophrenia - with an odds ratio of 3.9 (p < .01, CI = 1.3-1

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Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer.
Tabarés-Seisdedos R, Rubenstein JL. Tabarés-Seisdedos R, et al. Mol Psychiatry. 2009 Jun;14(6):563-89. doi: 10.1038/mp.2009.2. Epub 2009 Feb 10. Mol Psychiatry. 2009. PMID: 19204725 Review.
Defects in genetic and developmental processes are thought to contribute susceptibility to autism and schizophrenia. Presumably, owing to etiological complexity identifying susceptibility genes and abnormalities in the development has been difficult. ...Molecular genetics …
Defects in genetic and developmental processes are thought to contribute susceptibility to autism and schizophrenia. Presumably, owin …