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Items: 1 to 20 of 208

1.

The reason sickle reticulocytes expose PS.

Discher DE, Ney PA.

Blood. 2015 Oct 8;126(15):1737-8. doi: 10.1182/blood-2015-08-665117.

PMID:
26450953
2.

Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.

Sosale NG, Spinler KR, Alvey C, Discher DE.

Curr Opin Immunol. 2015 Aug;35:107-12. doi: 10.1016/j.coi.2015.06.013. Epub 2015 Jul 13. Review.

PMID:
26172292
3.

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor.

Dingal PC, Bradshaw AM, Cho S, Raab M, Buxboim A, Swift J, Discher DE.

Nat Mater. 2015 Sep;14(9):951-60. doi: 10.1038/nmat4350. Epub 2015 Jul 13.

4.

Stem cell mechanobiology: diverse lessons from bone marrow.

Ivanovska IL, Shin JW, Swift J, Discher DE.

Trends Cell Biol. 2015 Sep;25(9):523-32. doi: 10.1016/j.tcb.2015.04.003. Epub 2015 Jun 2. Review.

PMID:
26045259
5.
6.

Cell motion and mechanobiology.

Paluch EK, Discher DE.

Mol Biol Cell. 2015 Mar 15;26(6):1011. doi: 10.1091/mbc.E14-12-1590. No abstract available.

7.

Substrate stiffness-modulated registry phase correlations in cardiomyocytes map structural order to coherent beating.

Dasbiswas K, Majkut S, Discher DE, Safran SA.

Nat Commun. 2015 Jan 19;6:6085. doi: 10.1038/ncomms7085.

PMID:
25597833
8.

Simple insoluble cues specify stem cell differentiation.

Dingal PC, Wells RG, Discher DE.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18104-5. doi: 10.1073/pnas.1421562112. Epub 2014 Dec 15. No abstract available.

9.

Systems mechanobiology: tension-inhibited protein turnover is sufficient to physically control gene circuits.

Dingal PC, Discher DE.

Biophys J. 2014 Dec 2;107(11):2734-43. doi: 10.1016/j.bpj.2014.10.042. Epub 2014 Dec 2.

10.

Cell rigidity and shape override CD47's "self"-signaling in phagocytosis by hyperactivating myosin-II.

Sosale NG, Rouhiparkouhi T, Bradshaw AM, Dimova R, Lipowsky R, Discher DE.

Blood. 2015 Jan 15;125(3):542-52. doi: 10.1182/blood-2014-06-585299. Epub 2014 Nov 19.

11.

Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia.

Spinler KR, Shin JW, Lambert MP, Discher DE.

Blood. 2015 Jan 15;125(3):525-33. doi: 10.1182/blood-2014-05-576462. Epub 2014 Nov 13.

12.

TCR triggering by pMHC ligands tethered on surfaces via poly(ethylene glycol) depends on polymer length.

Ma Z, LeBard DN, Loverde SM, Sharp KA, Klein ML, Discher DE, Finkel TH.

PLoS One. 2014 Nov 10;9(11):e112292. doi: 10.1371/journal.pone.0112292. eCollection 2014.

14.

Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin.

Buxboim A, Swift J, Irianto J, Spinler KR, Dingal PC, Athirasala A, Kao YR, Cho S, Harada T, Shin JW, Discher DE.

Curr Biol. 2014 Aug 18;24(16):1909-17. doi: 10.1016/j.cub.2014.07.001. Epub 2014 Aug 7.

15.

The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue.

Swift J, Discher DE.

J Cell Sci. 2014 Jul 15;127(Pt 14):3005-15. doi: 10.1242/jcs.149203. Epub 2014 Jun 24. Review.

16.

From stealthy polymersomes and filomicelles to "self" Peptide-nanoparticles for cancer therapy.

Oltra NS, Nair P, Discher DE.

Annu Rev Chem Biomol Eng. 2014;5:281-99. doi: 10.1146/annurev-chembioeng-060713-040447. Review.

17.

Combining insoluble and soluble factors to steer stem cell fate.

Dingal PC, Discher DE.

Nat Mater. 2014 Jun;13(6):532-7. doi: 10.1038/nmat3997. Review. No abstract available.

PMID:
24845982
18.

Stress sensitivity and mechanotransduction during heart development.

Majkut S, Dingal PC, Discher DE.

Curr Biol. 2014 May 19;24(10):R495-501. doi: 10.1016/j.cub.2014.04.027. Review.

19.

Material control of stem cell differentiation: challenges in nano-characterization.

Dingal PC, Discher DE.

Curr Opin Biotechnol. 2014 Aug;28:46-50. doi: 10.1016/j.copbio.2013.11.003. Epub 2013 Nov 25. Review.

PMID:
24832074
20.

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PC, Ivanovska IL, Discher DE.

J Cell Biol. 2014 Mar 3;204(5):669-82. doi: 10.1083/jcb.201308029. Epub 2014 Feb 24.

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