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Results: 1 to 20 of 189

1.

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

Harada T, Swift J, Irianto J, Shin JW, Spinler KR, Athirasala A, Diegmiller R, Dingal PC, Ivanovska IL, Discher DE.

J Cell Biol. 2014 Mar 3;204(5):669-82. doi: 10.1083/jcb.201308029. Epub 2014 Feb 24.

PMID:
24567359
[PubMed - in process]
2.

Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells.

Swift J, Harada T, Buxboim A, Shin JW, Tang HY, Speicher DW, Discher DE.

Nucleus. 2013 Nov-Dec;4(6):450-9. doi: 10.4161/nucl.27413. Epub 2013 Dec 6.

PMID:
24448480
[PubMed - in process]
3.

Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells.

Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE.

Cell Stem Cell. 2014 Jan 2;14(1):81-93. doi: 10.1016/j.stem.2013.10.009. Epub 2013 Nov 21.

PMID:
24268694
[PubMed - in process]
4.

Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating.

Majkut S, Idema T, Swift J, Krieger C, Liu A, Discher DE.

Curr Biol. 2013 Dec 2;23(23):2434-9. doi: 10.1016/j.cub.2013.10.057. Epub 2013 Nov 21.

PMID:
24268417
[PubMed - in process]
5.

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.

Shin JW, Spinler KR, Swift J, Chasis JA, Mohandas N, Discher DE.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18892-7. doi: 10.1073/pnas.1304996110. Epub 2013 Nov 4.

PMID:
24191023
[PubMed - indexed for MEDLINE]
6.

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.

Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, Rehfeldt F, Speicher DW, Discher DE.

Science. 2013 Aug 30;341(6149):1240104. doi: 10.1126/science.1240104.

PMID:
23990565
[PubMed - indexed for MEDLINE]
7.

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

Suzuki A, Shin JW, Wang Y, Min SH, Poncz M, Choi JK, Discher DE, Carpenter CL, Lian L, Zhao L, Wang Y, Abrams CS.

PLoS One. 2013 Jul 23;8(7):e69315. doi: 10.1371/journal.pone.0069315. Print 2013.

PMID:
23935982
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates.

Shin JW, Swift J, Ivanovska I, Spinler KR, Buxboim A, Discher DE.

Differentiation. 2013 Oct;86(3):77-86. doi: 10.1016/j.diff.2013.05.001. Epub 2013 Jun 19.

PMID:
23790394
[PubMed - in process]
9.

Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes.

Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE, Lee DA.

Biophys J. 2013 Feb 19;104(4):759-69. doi: 10.1016/j.bpj.2013.01.006.

PMID:
23442954
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles.

Rodriguez PL, Harada T, Christian DA, Pantano DA, Tsai RK, Discher DE.

Science. 2013 Feb 22;339(6122):971-5. doi: 10.1126/science.1229568.

PMID:
23430657
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Adhesion-induced phase behavior of two-component membranes and vesicles.

Rouhiparkouhi T, Weikl TR, Discher DE, Lipowsky R.

Int J Mol Sci. 2013 Jan 22;14(1):2203-29. doi: 10.3390/ijms14012203.

PMID:
23340655
[PubMed]
Free PMC Article
12.

Dynamic domains in polymersomes: mixtures of polyanionic and neutral diblocks respond more rapidly to changes in calcium than to pH.

Spinler K, Tian A, Christian DA, Pantano DA, Baumgart T, Discher DE.

Langmuir. 2013 Jun 18;29(24):7499-508. doi: 10.1021/la304602e. Epub 2013 Feb 11.

PMID:
23327600
[PubMed - indexed for MEDLINE]
13.

Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy.

Baumann BC, Kao GD, Mahmud A, Harada T, Swift J, Chapman C, Xu X, Discher DE, Dorsey JF.

Oncotarget. 2013 Jan;4(1):64-79.

PMID:
23296073
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.

Raab M, Swift J, Dingal PC, Shah P, Shin JW, Discher DE.

J Cell Biol. 2012 Nov 12;199(4):669-83. doi: 10.1083/jcb.201205056. Epub 2012 Nov 5.

PMID:
23128239
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mechanical force in T cell receptor signal initiation.

Ma Z, Discher DE, Finkel TH.

Front Immunol. 2012 Jul 20;3:217. doi: 10.3389/fimmu.2012.00217. eCollection 2012. No abstract available.

PMID:
22833746
[PubMed]
Free PMC Article
16.

Cell culture: Soft gels select tumorigenic cells.

Shin JW, Discher DE.

Nat Mater. 2012 Jul 24;11(8):662-3. doi: 10.1038/nmat3388. No abstract available.

PMID:
22825018
[PubMed - indexed for MEDLINE]
17.

Cardiomyocytes from late embryos and neonates do optimal work and striate best on substrates with tissue-level elasticity: metrics and mathematics.

Majkut SF, Discher DE.

Biomech Model Mechanobiol. 2012 Nov;11(8):1219-25. doi: 10.1007/s10237-012-0413-8. Epub 2012 Jul 3.

PMID:
22752667
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Marker-of-self becomes marker-of-senescence.

Sosale N, Discher DE.

Blood. 2012 Jun 7;119(23):5343-4. doi: 10.1182/blood-2012-04-418608. No abstract available.

PMID:
22679336
[PubMed - indexed for MEDLINE]
Free Article
19.

Subcellular organization: change of phase in partitioning the cellular milieu.

Swift J, Discher DE.

Curr Biol. 2012 Mar 20;22(6):R188-90. doi: 10.1016/j.cub.2012.02.008.

PMID:
22440801
[PubMed - indexed for MEDLINE]
20.

Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells.

Rehfeldt F, Brown AE, Raab M, Cai S, Zajac AL, Zemel A, Discher DE.

Integr Biol (Camb). 2012 Apr;4(4):422-30. doi: 10.1039/c2ib00150k. Epub 2012 Feb 20.

PMID:
22344328
[PubMed - indexed for MEDLINE]

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