PubMed

Conformational changes and signaling in cell and matrix physics.

Brown AE, Discher DE.

Curr Biol. 2009 Sep 15;19(17):R781-9.PMID: 19906580 [PubMed - in process]Related articles

Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding.

Christian DA, Tian A, Ellenbroek WG, Levental I, Rajagopal K, Janmey PA, Liu AJ, Baumgart T, Discher DE.

Nat Mater. 2009 Oct;8(10):843-9. Epub 2009 Sep 6.PMID: 19734886 [PubMed - indexed for MEDLINE]Related articles

Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water.

Brown AE, Litvinov RI, Discher DE, Purohit PK, Weisel JW.

Science. 2009 Aug 7;325(5941):741-4.PMID: 19661428 [PubMed - indexed for MEDLINE]Related articles

Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers.

Levental I, Christian DA, Wang YH, Madara JJ, Discher DE, Janmey PA.

Biochemistry. 2009 Sep 1;48(34):8241-8.PMID: 19630438 [PubMed - indexed for MEDLINE]Related articles

Stem cells, microenvironment mechanics, and growth factor activation.

Tenney RM, Discher DE.

Curr Opin Cell Biol. 2009 Oct;21(5):630-5. Epub 2009 Jul 15. Review.PMID: 19615877 [PubMed - indexed for MEDLINE]Related articles

Growth factors, matrices, and forces combine and control stem cells.

Discher DE, Mooney DJ, Zandstra PW.

Science. 2009 Jun 26;324(5935):1673-7. Review.PMID: 19556500 [PubMed - indexed for MEDLINE]Related articles

Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.

Simone EA, Dziubla TD, Discher DE, Muzykantov VR.

Biomacromolecules. 2009 Jun 8;10(6):1324-30.PMID: 19385657 [PubMed - indexed for MEDLINE]Related articles

Biomechanics: cell research and applications for the next decade.

Discher D, Dong C, Fredberg JJ, Guilak F, Ingber D, Janmey P, Kamm RD, Schmid-Schönbein GW, Weinbaum S.

Ann Biomed Eng. 2009 May;37(5):847-59. Epub 2009 Mar 4.PMID: 19259817 [PubMed - indexed for MEDLINE]Related articles

Cross-correlated TIRF/AFM reveals asymmetric distribution of force-generating heads along self-assembled, "synthetic" myosin filaments.

Brown AE, Hategan A, Safer D, Goldman YE, Discher DE.

Biophys J. 2009 Mar 4;96(5):1952-60.PMID: 19254555 [PubMed - indexed for MEDLINE]Related articles

Flexible filaments for in vivo imaging and delivery: persistent circulation of filomicelles opens the dosage window for sustained tumor shrinkage.

Christian DA, Cai S, Garbuzenko OB, Harada T, Zajac AL, Minko T, Discher DE.

Mol Pharm. 2009 Sep-Oct;6(5):1343-52.PMID: 19249859 [PubMed - in process]Related articles

Polymersome delivery of siRNA and antisense oligonucleotides.

Kim Y, Tewari M, Pajerowski JD, Cai S, Sen S, Williams JH, Sirsi SR, Lutz GJ, Discher DE.

J Control Release. 2009 Mar 4;134(2):132-40. Epub 2008 Nov 12. Erratum in: J Control Release. 2009 Aug 4;137(3):256. Williams, Jason [corrected to Williams, Jason H]; Sirsi, Shashank, [corrected to Sirsi, Shashank R]; Lutz, Gordon [corrected to Lutz, Gordon J]. PMID: 19084037 [PubMed - indexed for MEDLINE]Related articles

Polymersome carriers: from self-assembly to siRNA and protein therapeutics.

Christian DA, Cai S, Bowen DM, Kim Y, Pajerowski JD, Discher DE.

Eur J Pharm Biopharm. 2009 Mar;71(3):463-74. Epub 2008 Oct 17. Review.PMID: 18977437 [PubMed - indexed for MEDLINE]Related articles

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating.

Engler AJ, Carag-Krieger C, Johnson CP, Raab M, Tang HY, Speicher DW, Sanger JW, Sanger JM, Discher DE.

J Cell Sci. 2008 Nov 15;121(Pt 22):3794-802. Epub 2008 Oct 28.PMID: 18957515 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell differentiation through tissue elasticity-coupled, myosin-driven remodeling.

Zajac AL, Discher DE.

Curr Opin Cell Biol. 2008 Dec;20(6):609-15. Epub 2008 Oct 25. Review.PMID: 18926907 [PubMed - indexed for MEDLINE]Related articles

Shape effects of filaments versus spherical particles in flow and drug delivery.

Geng Y, Dalhaimer P, Cai S, Tsai R, Tewari M, Minko T, Discher DE.

Nat Nanotechnol. 2007 Apr;2(4):249-55. Epub 2007 Mar 25.PMID: 18654271 [PubMed - indexed for MEDLINE]Related articlesFree article

Cys shotgun labeling of macrophages adhering to and engulfing Ig-opsonized cells.

Tsai R, Rodriguez P, Discher DE.

Transfus Clin Biol. 2008 Feb-Mar;15(1-2):58-61. Epub 2008 May 21.PMID: 18499497 [PubMed - indexed for MEDLINE]Related articles

Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet.

Wells RG, Discher DE.

Sci Signal. 2008 Mar 11;1(10):pe13. Review.PMID: 18334714 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells.

Tsai RK, Discher DE.

J Cell Biol. 2008 Mar 10;180(5):989-1003.PMID: 18332220 [PubMed - indexed for MEDLINE]Related articlesFree article

Extracellular matrix elasticity directs stem cell differentiation.

Engler AJ, Sweeney HL, Discher DE, Schwarzbauer JE.

J Musculoskelet Neuronal Interact. 2007 Oct-Dec;7(4):335. No abstract available. PMID: 18094500 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of polymer amphiphilicity on loading of a therapeutic enzyme into protective filamentous and spherical polymer nanocarriers.

Simone EA, Dziubla TD, Colon-Gonzalez F, Discher DE, Muzykantov VR.

Biomacromolecules. 2007 Dec;8(12):3914-21. Epub 2007 Nov 27.PMID: 18038999 [PubMed - indexed for MEDLINE]Related articles