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  • Showing results for diindolylmethane breast cancer. Your search for diindolemethane breast cancer retrieved no results.

The effect of oral 3,3'-diindolylmethane supplementation on the 2:16α-OHE ratio in BRCA1 mutation carriers.

Nikitina D, Llacuachaqui M, Sepkovic D, Bradlow HL, Narod SA, Kotsopoulos J.

Fam Cancer. 2015 Jun;14(2):281-6. doi: 10.1007/s10689-015-9783-2.


Low levels of 3,3'-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol.

Marques M, Laflamme L, Benassou I, Cissokho C, Guillemette B, Gaudreau L.

BMC Cancer. 2014 Jul 21;14:524. doi: 10.1186/1471-2407-14-524.


BRCA1 mRNA levels following a 4-6-week intervention with oral 3,3'-diindolylmethane.

Kotsopoulos J, Zhang S, Akbari M, Salmena L, Llacuachaqui M, Zeligs M, Sun P, Narod SA.

Br J Cancer. 2014 Sep 23;111(7):1269-74. doi: 10.1038/bjc.2014.391. Epub 2014 Jul 15.


Comparative preclinical pharmacokinetics study of 3,3'-diindolylmethane formulations: is personalized treatment and targeted chemoprevention in the horizon?

Paltsev M, Kiselev V, Muyzhnek E, Drukh V, Kuznetsov I, Pchelintseva O.

EPMA J. 2013 Dec 10;4(1):25. doi: 10.1186/1878-5085-4-25.


DIM (3,3'-diindolylmethane) confers protection against ionizing radiation by a unique mechanism.

Fan S, Meng Q, Xu J, Jiao Y, Zhao L, Zhang X, Sarkar FH, Brown ML, Dritschilo A, Rosen EM.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18650-5. doi: 10.1073/pnas.1308206110. Epub 2013 Oct 14.


3,3'-diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells.

Nicastro HL, Firestone GL, Bjeldanes LF.

J Nutr Biochem. 2013 Nov;24(11):1882-8. doi: 10.1016/j.jnutbio.2013.05.004. Epub 2013 Aug 19.


Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumors.

Wu TY, Khor TO, Su ZY, Saw CL, Shu L, Cheung KL, Huang Y, Yu S, Kong AN.

AAPS J. 2013 Jul;15(3):864-74. doi: 10.1208/s12248-013-9493-3. Epub 2013 May 9.


The aryl hydrocarbon receptor and estrogen receptor alpha differentially modulate nuclear factor erythroid-2-related factor 2 transactivation in MCF-7 breast cancer cells.

Lo R, Matthews J.

Toxicol Appl Pharmacol. 2013 Jul 15;270(2):139-48. doi: 10.1016/j.taap.2013.03.029. Epub 2013 Apr 11.


2,2'-diphenyl-3,3'-diindolylmethane: a potent compound induces apoptosis in breast cancer cells by inhibiting EGFR pathway.

Bhowmik A, Das N, Pal U, Mandal M, Bhattacharya S, Sarkar M, Jaisankar P, Maiti NC, Ghosh MK.

PLoS One. 2013;8(3):e59798. doi: 10.1371/journal.pone.0059798. Epub 2013 Mar 28.


3,3'-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway.

Yao Z, Hu W, Yin S, Huang Z, Zhu Q, Chen J, Zang Y, Dong L, Zhang J.

Pharmacol Res. 2013 Apr;70(1):139-46. doi: 10.1016/j.phrs.2013.01.006. Epub 2013 Jan 31.


3, 3'-Diindolylmethane enhances the effectiveness of herceptin against HER-2/neu-expressing breast cancer cells.

Ahmad A, Ali S, Ahmed A, Ali AS, Raz A, Sakr WA, Rahman KM.

PLoS One. 2013;8(1):e54657. doi: 10.1371/journal.pone.0054657. Epub 2013 Jan 22.


Indole compounds against breast cancer: recent developments.

Biersack B, Schobert R.

Curr Drug Targets. 2012 Dec;13(14):1705-19. Review.


Modulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,3'-diindolylmethene in human breast epithelial cell lines.

Licznerska BE, Szaefer H, Murias M, Bartoszek A, Baer-Dubowska W.

Eur J Nutr. 2013 Aug;52(5):1483-92. doi: 10.1007/s00394-012-0455-9. Epub 2012 Oct 23. Erratum in: Eur J Nutr. 2014 Apr;53(3):995.


BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer.

Jiang J, Thyagarajan-Sahu A, Loganathan J, Eliaz I, Terry C, Sandusky GE, Sliva D.

Oncol Rep. 2012 Oct;28(4):1139-45. doi: 10.3892/or.2012.1936. Epub 2012 Jul 26.


Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines.

Szaefer H, Licznerska B, Krajka-Kuźniak V, Bartoszek A, Baer-Dubowska W.

Nutr Cancer. 2012 Aug;64(6):879-88. doi: 10.1080/01635581.2012.690928. Epub 2012 Jun 20.


Molecular target based combinational therapeutic approaches in thyroid cancer.

Rajoria S, Suriano R, George AL, Kamat A, Schantz SP, Geliebter J, Tiwari RK.

J Transl Med. 2012 May 1;10:81. doi: 10.1186/1479-5876-10-81.


Inhibition of fatty acid synthase and Sp1 expression by 3,3'-diindolylmethane in human breast cancer cells.

Saati GE, Archer MC.

Nutr Cancer. 2011;63(5):790-4. doi: 10.1080/01635581.2011.570896. Epub 2011 Jun 22.


3,3'-Diindolylmethane inhibits breast cancer cell growth via miR-21-mediated Cdc25A degradation.

Jin Y.

Mol Cell Biochem. 2011 Dec;358(1-2):345-54. doi: 10.1007/s11010-011-0985-0. Epub 2011 Jul 15.


3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells: retraction.

[No authors listed]

Anticancer Drugs. 2011 Mar;22(3):303. doi: 10.1097/CAD.0b013e328344b81f. No abstract available.


3,3'-Diindolylmethane enhances taxotere-induced growth inhibition of breast cancer cells through downregulation of FoxM1.

Ahmad A, Ali S, Wang Z, Ali AS, Sethi S, Sakr WA, Raz A, Rahman KM.

Int J Cancer. 2011 Oct 1;129(7):1781-91. doi: 10.1002/ijc.25839. Epub 2011 Mar 8. Erratum in: Int J Cancer. 2014 Nov 1;135(9):E10.

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