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Items: 1 to 20 of 74

1.

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.

Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L.

Oncotarget. 2016 Aug 16. doi: 10.18632/oncotarget.11318. [Epub ahead of print]

2.

Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.

De Leo MG, Staiano L, Vicinanza M, Luciani A, Carissimo A, Mutarelli M, Di Campli A, Polishchuk E, Di Tullio G, Morra V, Levtchenko E, Oltrabella F, Starborg T, Santoro M, di Bernardo D, Devuyst O, Lowe M, Medina DL, Ballabio A, De Matteis MA.

Nat Cell Biol. 2016 Aug;18(8):839-50. doi: 10.1038/ncb3386. Epub 2016 Jul 11.

PMID:
27398910
3.
4.

In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis.

Pagliarini R, Castello R, Napolitano F, Borzone R, Annunziata P, Mandrile G, De Marchi M, Brunetti-Pierri N, di Bernardo D.

Cell Rep. 2016 Jun 7;15(10):2292-300. doi: 10.1016/j.celrep.2016.05.014. Epub 2016 May 26.

5.

An atlas of gene expression and gene co-regulation in the human retina.

Pinelli M, Carissimo A, Cutillo L, Lai CH, Mutarelli M, Moretti MN, Singh MV, Karali M, Carrella D, Pizzo M, Russo F, Ferrari S, Ponzin D, Angelini C, Banfi S, di Bernardo D.

Nucleic Acids Res. 2016 Jul 8;44(12):5773-84. doi: 10.1093/nar/gkw486. Epub 2016 May 27.

6.

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel.

Pesce E, Gorrieri G, Sirci F, Napolitano F, Carrella D, Caci E, Tomati V, Zegarra-Moran O, di Bernardo D, Galietta LJ.

J Cyst Fibros. 2016 Jul;15(4):425-35. doi: 10.1016/j.jcf.2016.02.009. Epub 2016 Mar 10.

PMID:
26971626
7.

High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs.

Karali M, Persico M, Mutarelli M, Carissimo A, Pizzo M, Singh Marwah V, Ambrosio C, Pinelli M, Carrella D, Ferrari S, Ponzin D, Nigro V, di Bernardo D, Banfi S.

Nucleic Acids Res. 2016 Feb 29;44(4):1525-40. doi: 10.1093/nar/gkw039. Epub 2016 Jan 26.

8.

Unravelling druggable signalling networks that control F508del-CFTR proteostasis.

Hegde RN, Parashuraman S, Iorio F, Ciciriello F, Capuani F, Carissimo A, Carrella D, Belcastro V, Subramanian A, Bounti L, Persico M, Carlile G, Galietta L, Thomas DY, Di Bernardo D, Luini A.

Elife. 2015 Dec 23;4. pii: e10365. doi: 10.7554/eLife.10365.

9.

In Vivo Real-Time Control of Gene Expression: A Comparative Analysis of Feedback Control Strategies in Yeast.

Fiore G, Perrino G, di Bernardo M, di Bernardo D.

ACS Synth Biol. 2016 Feb 19;5(2):154-62. doi: 10.1021/acssynbio.5b00135. Epub 2015 Dec 4.

PMID:
26554583
10.

Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress.

Tebbi A, Levillayer F, Jouvion G, Fiette L, Soubigou G, Varet H, Boudjadja N, Cairo S, Hashimoto K, Suzuki AM, Carninci P, Carissimo A, di Bernardo D, Wei Y.

Carcinogenesis. 2016 Jan;37(1):39-48. doi: 10.1093/carcin/bgv156. Epub 2015 Nov 5.

11.

Blood transcriptomics of drug-naïve sporadic Parkinson's disease patients.

Calligaris R, Banica M, Roncaglia P, Robotti E, Finaurini S, Vlachouli C, Antonutti L, Iorio F, Carissimo A, Cattaruzza T, Ceiner A, Lazarevic D, Cucca A, Pangher N, Marengo E, di Bernardo D, Pizzolato G, Gustincich S.

BMC Genomics. 2015 Oct 28;16:876. doi: 10.1186/s12864-015-2058-3.

12.

Drug-set enrichment analysis: a novel tool to investigate drug mode of action.

Napolitano F, Sirci F, Carrella D, di Bernardo D.

Bioinformatics. 2016 Jan 15;32(2):235-41. doi: 10.1093/bioinformatics/btv536. Epub 2015 Sep 28.

13.

Automatic Control of Gene Expression in Mammalian Cells.

Fracassi C, Postiglione L, Fiore G, di Bernardo D.

ACS Synth Biol. 2016 Apr 15;5(4):296-302. doi: 10.1021/acssynbio.5b00141. Epub 2015 Oct 6.

PMID:
26414746
14.

A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data.

Gambardella G, Peluso I, Montefusco S, Bansal M, Medina DL, Lawrence N, di Bernardo D.

BMC Bioinformatics. 2015 Sep 3;16:279. doi: 10.1186/s12859-015-0700-3.

15.

Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species.

Ventre S, Indrieri A, Fracassi C, Franco B, Conte I, Cardone L, di Bernardo D.

J Mol Biol. 2015 May 22;427(10):1887-902. doi: 10.1016/j.jmb.2015.03.007. Epub 2015 Mar 18.

PMID:
25796437
16.

Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.

Racioppi C, Kamal AK, Razy-Krajka F, Gambardella G, Zanetti L, di Bernardo D, Sanges R, Christiaen LA, Ristoratore F.

Nat Commun. 2014 Sep 5;5:4830. doi: 10.1038/ncomms5830.

17.

A network-based approach to dissect the cilia/centrosome complex interactome.

Amato R, Morleo M, Giaquinto L, di Bernardo D, Franco B.

BMC Genomics. 2014 Aug 7;15:658. doi: 10.1186/1471-2164-15-658.

18.

A community-based resource for automatic exome variant-calling and annotation in Mendelian disorders.

Mutarelli M, Marwah V, Rispoli R, Carrella D, Dharmalingam G, Oliva G, di Bernardo D.

BMC Genomics. 2014;15 Suppl 3:S5. doi: 10.1186/1471-2164-15-S3-S5. Epub 2014 May 6.

19.

In-vivo real-time control of protein expression from endogenous and synthetic gene networks.

Menolascina F, Fiore G, Orabona E, De Stefano L, Ferry M, Hasty J, di Bernardo M, di Bernardo D.

PLoS Comput Biol. 2014 May 15;10(5):e1003625. doi: 10.1371/journal.pcbi.1003625. eCollection 2014 May.

20.

The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation.

Moskot M, Montefusco S, Jakóbkiewicz-Banecka J, Mozolewski P, Węgrzyn A, Di Bernardo D, Węgrzyn G, Medina DL, Ballabio A, Gabig-Cimińska M.

J Biol Chem. 2014 Jun 13;289(24):17054-69. doi: 10.1074/jbc.M114.555300. Epub 2014 Apr 25.

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