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Results: 1 to 20 of 83

1.

An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation.

Lu C, Ward A, Bettridge J, Liu Y, Desiderio S.

Cell Rep. 2015 Jan 6;10(1):29-38. doi: 10.1016/j.celrep.2014.12.001. Epub 2014 Dec 24.

2.

Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies.

Halper-Stromberg E, Steranka J, Giraldo-Castillo N, Fuller T, Desiderio S, Burns KH.

BMC Genomics. 2013 Aug 19;14:565. doi: 10.1186/1471-2164-14-565.

3.

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

Rybanska-Spaeder I, Reynolds TL, Chou J, Prakash M, Jefferson T, Huso DL, Desiderio S, Franco S.

Mol Cancer Res. 2013 Oct;11(10):1223-34. doi: 10.1158/1541-7786.MCR-13-0252-T. Epub 2013 Jul 15.

4.

Stat3β mitigates development of atherosclerosis in apolipoprotein E-deficient mice.

Lee J, Baldwin WM 3rd, Lee CY, Desiderio S.

J Mol Med (Berl). 2013 Aug;91(8):965-76. doi: 10.1007/s00109-013-1013-5. Epub 2013 Apr 26.

5.

Construction of human activity-based phosphorylation networks.

Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, Ni Q, Goel R, Xia S, Ji H, Dalby KN, Birnbaum MJ, Cole PA, Knapp S, Ryazanov AG, Zack DJ, Blackshaw S, Pawson T, Gingras AC, Desiderio S, Pandey A, Turk BE, Zhang J, Zhu H, Qian J.

Mol Syst Biol. 2013;9:655. doi: 10.1038/msb.2013.12.

6.

The transcriptional repressor NKAP is required for the development of iNKT cells.

Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS.

Nat Commun. 2013;4:1582. doi: 10.1038/ncomms2580.

7.

Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.

Cooper CL, Hardy RR, Reth M, Desiderio S.

Blood. 2012 Jun 7;119(23):5438-48. doi: 10.1182/blood-2011-12-397976. Epub 2012 Apr 18.

8.

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D.

Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8.

9.

Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.

Zhang L, Reynolds TL, Shan X, Desiderio S.

Immunity. 2011 Feb 25;34(2):163-74. doi: 10.1016/j.immuni.2011.02.003.

10.

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.

Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D.

Blood. 2011 Mar 17;117(11):3131-9. doi: 10.1182/blood-2010-05-286070. Epub 2011 Jan 12.

11.

Temporal and spatial regulatory functions of the V(D)J recombinase.

Desiderio S.

Semin Immunol. 2010 Dec;22(6):362-9. doi: 10.1016/j.smim.2010.09.001. Epub 2010 Oct 30. Review.

PMID:
21036059
12.

NetPath: a public resource of curated signal transduction pathways.

Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A.

Genome Biol. 2010 Jan 12;11(1):R3. doi: 10.1186/gb-2010-11-1-r3.

13.
14.

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M.

J Biol Chem. 2009 Jul 17;284(29):19437-44. doi: 10.1074/jbc.M109.006098. Epub 2009 May 27.

15.

Along came a spider: AID escapes a microRNA web.

Desiderio S.

Immunity. 2008 May;28(5):596-8. doi: 10.1016/j.immuni.2008.04.012.

16.

The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II.

Marton HA, Desiderio S.

BMC Mol Biol. 2008 Jan 14;9:4. doi: 10.1186/1471-2199-9-4.

17.

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.

Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S.

Immunity. 2007 Oct;27(4):561-71. Epub 2007 Oct 11.

18.

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions.

Youn MY, Yoo HS, Kim MJ, Hwang SY, Choi Y, Desiderio SV, Yoo JY.

J Biol Chem. 2007 Nov 30;282(48):34727-34. Epub 2007 Oct 1.

19.

Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S.

Science. 2006 Oct 6;314(5796):122-5.

20.

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.

Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Nakayama K, Desiderio S.

Mol Cell. 2005 Jun 10;18(6):699-709.

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