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Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis.

Whiteley WN, Emberson J, Lees KR, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg MG, Lindley RI, Lyden P, Olivot JM, Parsons M, Toni D, Toyoda K, Wahlgren N, Wardlaw J, Del Zoppo GJ, Sandercock P, Hacke W, Baigent C; Stroke Thrombolysis Trialists' Collaboration.

Lancet Neurol. 2016 Jun 8. pii: S1474-4422(16)30076-X. doi: 10.1016/S1474-4422(16)30076-X. [Epub ahead of print]


Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation.

Grottke O, Aisenberg J, Bernstein R, Goldstein P, Huisman MV, Jamieson DG, Levy JH, Pollack CV Jr, Spyropoulos AC, Steiner T, Del Zoppo GJ, Eikelboom J.

Crit Care. 2016 Apr 28;20(1):115. doi: 10.1186/s13054-016-1275-8. Review.


Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine.

Frontera JA, Lewin JJ 3rd, Rabinstein AA, Aisiku IP, Alexandrov AW, Cook AM, del Zoppo GJ, Kumar MA, Peerschke EI, Stiefel MF, Teitelbaum JS, Wartenberg KE, Zerfoss CL.

Neurocrit Care. 2016 Feb;24(1):6-46. doi: 10.1007/s12028-015-0222-x.


Exploring phlebotomy technique as a pre-analytical factor in proteomic analyses by mass spectrometry.

Penn AM, Lu L, Chambers AG, Balshaw RF, Morrison JL, Votova K, Wood E, Smith DS, Lesperance M, del Zoppo GJ, Borchers CH; SpecTRA Study Group.

Genome. 2015 Dec;58(12):569-76. doi: 10.1139/gen-2015-0036. Epub 2015 Jul 10.


Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia.

Gu YH, Kanazawa M, Hung SY, Wang X, Fukuda S, Koziol JA, Del Zoppo GJ.

J Cereb Blood Flow Metab. 2015 Nov;35(11):1888-900. doi: 10.1038/jcbfm.2015.170. Epub 2015 Jul 22.


Quality of anticoagulation control in preventing adverse events in patients with heart failure in sinus rhythm: Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial substudy.

Homma S, Thompson JL, Qian M, Ye S, Di Tullio MR, Lip GY, Mann DL, Sacco RL, Levin B, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Mohr JP, Labovitz AJ, Buchsbaum R, Estol CJ, Lok DJ, Ponikowski P, Anker SD; WARCEF Investigators.

Circ Heart Fail. 2015 May;8(3):504-9. doi: 10.1161/CIRCHEARTFAILURE.114.001725. Epub 2015 Apr 7.


Dabigatran abrogates brain endothelial cell permeability in response to thrombin.

Hawkins BT, Gu YH, Izawa Y, del Zoppo GJ.

J Cereb Blood Flow Metab. 2015 Jun;35(6):985-92. doi: 10.1038/jcbfm.2015.9. Epub 2015 Feb 11.


Recurrent stroke in the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial.

Pullicino PM, Qian M, Sacco RL, Freudenberger R, Graham S, Teerlink JR, Mann D, Di Tullio MR, Ponikowski P, Lok DJ, Anker SD, Lip GY, Estol CJ, Levin B, Mohr JP, Thompson JL, Homma S; WARCEF Investigators.

Cerebrovasc Dis. 2014;38(3):176-81. doi: 10.1159/000365502. Epub 2014 Oct 9.


Alteplase for ischaemic stroke--responses.

Wardlaw JM, Murray V, Berge E, Del Zoppo GJ.

Lancet. 2014 Aug 23;384(9944):661-2. doi: 10.1016/S0140-6736(14)61387-8. No abstract available.


Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.

Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg M, Lindley RI, Murray G, Olivot JM, Parsons M, Tilley B, Toni D, Toyoda K, Wahlgren N, Wardlaw J, Whiteley W, del Zoppo GJ, Baigent C, Sandercock P, Hacke W; Stroke Thrombolysis Trialists' Collaborative Group.

Lancet. 2014 Nov 29;384(9958):1929-35. doi: 10.1016/S0140-6736(14)60584-5. Epub 2014 Aug 5. Review.


Thrombolysis for acute ischaemic stroke.

Wardlaw JM, Murray V, Berge E, del Zoppo GJ.

Cochrane Database Syst Rev. 2014 Jul 29;(7):CD000213. doi: 10.1002/14651858.CD000213.pub3. Review.


Exploratory analysis of glyburide as a novel therapy for preventing brain swelling.

Sheth KN, Kimberly WT, Elm JJ, Kent TA, Yoo AJ, Thomalla G, Campbell B, Donnan GA, Davis SM, Albers GW, Jacobson S, del Zoppo G, Simard JM, Stern BJ, Mandava P.

Neurocrit Care. 2014 Aug;21(1):43-51. doi: 10.1007/s12028-014-9970-2.


Evolving role of endovascular treatment of acute ischemic stroke.

Ciccone A, del Zoppo GJ.

Curr Neurol Neurosci Rep. 2014 Jan;14(1):416. doi: 10.1007/s11910-013-0416-6. Review.


Hemostasis and alterations of the central nervous system.

del Zoppo GJ, Izawa Y, Hawkins BT.

Semin Thromb Hemost. 2013 Nov;39(8):856-75. doi: 10.1055/s-0033-1357490. Epub 2013 Oct 28. Review.


Glibenclamide in cerebral ischemia and stroke.

Simard JM, Sheth KN, Kimberly WT, Stern BJ, del Zoppo GJ, Jacobson S, Gerzanich V.

Neurocrit Care. 2014 Apr;20(2):319-33. doi: 10.1007/s12028-013-9923-1. Review.


Perioperative management of coagulation in nontraumatic intracerebral hemorrhage.

Degos V, Westbroek EM, Lawton MT, Hemphill JC 3rd, del Zoppo GJ, Young WL.

Anesthesiology. 2013 Jul;119(1):218-27. doi: 10.1097/ALN.0b013e318297c18a. Review. No abstract available.


Plasminogen activators and ischemic stroke: conditions for acute delivery.

del Zoppo GJ.

Semin Thromb Hemost. 2013 Jun;39(4):406-25. doi: 10.1055/s-0033-1338126. Epub 2013 Mar 28. Review.


TIMP-1 attenuates blood-brain barrier permeability in mice with acute liver failure.

Chen F, Radisky ES, Das P, Batra J, Hata T, Hori T, Baine AM, Gardner L, Yue MY, Bu G, del Zoppo G, Patel TC, Nguyen JH.

J Cereb Blood Flow Metab. 2013 Jul;33(7):1041-9. doi: 10.1038/jcbfm.2013.45. Epub 2013 Mar 27.


Polymorphonuclear neutrophil infiltration into ischemic infarctions: myth or truth?

Kalimo H, del Zoppo GJ, Paetau A, Lindsberg PJ.

Acta Neuropathol. 2013 Mar;125(3):313-6. doi: 10.1007/s00401-013-1098-5. No abstract available.

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