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Items: 1 to 20 of 114

1.

A family of metal-dependent phosphatases implicated in metabolite damage-control.

Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF 3rd, Joachimiak A, Savchenko A, Yakunin AF, Hanson AD.

Nat Chem Biol. 2016 Jun 20. doi: 10.1038/nchembio.2108. [Epub ahead of print]

PMID:
27322068
2.

Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite.

Thiaville JJ, Flood J, Yurgel S, Prunetti L, Elbadawi-Sidhu M, Hutinet G, Forouhar F, Zhang X, Ganesan V, Reddy P, Fiehn O, Gerlt JA, Hunt JF, Copley SD, de Crécy-Lagard V.

ACS Chem Biol. 2016 Jun 24. [Epub ahead of print]

PMID:
27294475
3.

'Nothing of chemistry disappears in biology': the Top 30 damage-prone endogenous metabolites.

Lerma-Ortiz C, Jeffryes JG, Cooper AJ, Niehaus TD, Thamm AM, Frelin O, Aunins T, Fiehn O, de Crécy-Lagard V, Henry CS, Hanson AD.

Biochem Soc Trans. 2016 Jun 15;44(3):961-71. doi: 10.1042/BST20160073. Review.

PMID:
27284066
4.

The Response of Acinetobacter baumannii to Zinc Starvation.

Nairn BL, Lonergan ZR, Wang J, Braymer JJ, Zhang Y, Calcutt MW, Lisher JP, Gilston BA, Chazin WJ, de Crécy-Lagard V, Giedroc DP, Skaar EP.

Cell Host Microbe. 2016 Jun 8;19(6):826-36. doi: 10.1016/j.chom.2016.05.007.

PMID:
27281572
5.

Experimental and Metabolic Modeling Evidence for a Folate-Cleaving Side-Activity of Ketopantoate Hydroxymethyltransferase (PanB).

Thiaville JJ, Frelin O, García-Salinas C, Harrison K, Hasnain G, Horenstein NA, Díaz de la Garza RI, Henry CS, Hanson AD, de Crécy-Lagard V.

Front Microbiol. 2016 Mar 31;7:431. doi: 10.3389/fmicb.2016.00431. eCollection 2016.

6.

tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs.

Machnicka MA, Dunin-Horkawicz S, de Crécy-Lagard V, Bujnicki JM.

Methods. 2016 Mar 23. pii: S1046-2023(16)30047-0. doi: 10.1016/j.ymeth.2016.03.013. [Epub ahead of print]

7.

Novel genomic island modifies DNA with 7-deazaguanine derivatives.

Thiaville JJ, Kellner SM, Yuan Y, Hutinet G, Thiaville PC, Jumpathong W, Mohapatra S, Brochier-Armanet C, Letarov AV, Hillebrand R, Malik CK, Rizzo CJ, Dedon PC, de Crécy-Lagard V.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1452-9. doi: 10.1073/pnas.1518570113. Epub 2016 Feb 29.

PMID:
26929322
8.

Evidence That COG0325 Proteins are involved in PLP Homeostasis.

Prunetti L, El Yacoubi B, Schiavon CR, Kirkpatrick E, Huang L, Bailly M, ElBadawi-Sidhu M, Harrison K, Gregory JF, Fiehn O, Hanson AD, de Crécy-Lagard V.

Microbiology. 2016 Feb 12. doi: 10.1099/mic.0.000255. [Epub ahead of print]

PMID:
26872910
9.

Global translational impacts of the loss of the tRNA modification t6A in yeast.

Thiaville PC, Legendre R, Rojas-Benítez D, Baudin-Baillieu A, Hatin I, Chalancon G, Glavic A, Namy O, de Crécy-Lagard V.

Microb Cell. 2016 Jan 1;3(1):29-45.

10.

Metabolite Damage and Metabolite Damage Control in Plants.

Hanson AD, Henry CS, Fiehn O, de Crécy-Lagard V.

Annu Rev Plant Biol. 2016 Apr 29;67:131-52. doi: 10.1146/annurev-arplant-043015-111648. Epub 2015 Nov 19.

PMID:
26667673
11.

Bacterial and plant HAD enzymes catalyse a missing phosphatase step in thiamin diphosphate biosynthesis.

Hasnain G, Roje S, Sa N, Zallot R, Ziemak MJ, de Crécy-Lagard V, Gregory JF 3rd, Hanson AD.

Biochem J. 2016 Jan 15;473(2):157-66. doi: 10.1042/BJ20150805. Epub 2015 Nov 4.

PMID:
26537753
12.

Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria.

Thiaville PC, El Yacoubi B, Köhrer C, Thiaville JJ, Deutsch C, Iwata-Reuyl D, Bacusmo JM, Armengaud J, Bessho Y, Wetzel C, Cao X, Limbach PA, RajBhandary UL, de Crécy-Lagard V.

Mol Microbiol. 2015 Dec;98(6):1199-221. doi: 10.1111/mmi.13209. Epub 2015 Oct 7.

PMID:
26337258
13.

Proteins of Unknown Biochemical Function: A Persistent Problem and a Roadmap to Help Overcome It.

Niehaus TD, Thamm AM, de Crécy-Lagard V, Hanson AD.

Plant Physiol. 2015 Nov;169(3):1436-42. doi: 10.1104/pp.15.00959. Epub 2015 Aug 12.

PMID:
26269542
14.

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.

Kuznetsova E, Nocek B, Brown G, Makarova KS, Flick R, Wolf YI, Khusnutdinova A, Evdokimova E, Jin K, Tan K, Hanson AD, Hasnain G, Zallot R, de Crécy-Lagard V, Babu M, Savchenko A, Joachimiak A, Edwards AM, Koonin EV, Yakunin AF.

J Biol Chem. 2015 Jul 24;290(30):18678-98. doi: 10.1074/jbc.M115.657916. Epub 2015 Jun 12.

PMID:
26071590
15.

The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth.

Rojas-Benitez D, Thiaville PC, de Crécy-Lagard V, Glavic A.

J Biol Chem. 2015 Jul 24;290(30):18699-707. doi: 10.1074/jbc.M115.665406. Epub 2015 Jun 10.

PMID:
26063805
16.

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes.

Magnúsdóttir S, Ravcheev D, de Crécy-Lagard V, Thiele I.

Front Genet. 2015 Apr 20;6:148. doi: 10.3389/fgene.2015.00148. eCollection 2015.

17.

The emerging role of complex modifications of tRNALys UUU in signaling pathways.

Thiaville PC, de Crécy-Lagard V.

Microb Cell. 2015 Jan;2(1):1-4. No abstract available.

18.

Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNA.

Thiaville PC, Iwata-Reuyl D, de Crécy-Lagard V.

RNA Biol. 2014;11(12):1529-39. doi: 10.4161/15476286.2014.992277. Review.

19.

A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis.

Frelin O, Huang L, Hasnain G, Jeffryes JG, Ziemak MJ, Rocca JR, Wang B, Rice J, Roje S, Yurgel SN, Gregory JF 3rd, Edison AS, Henry CS, de Crécy-Lagard V, Hanson AD.

Biochem J. 2015 Feb 15;466(1):137-45. doi: 10.1042/BJ20141237.

20.
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