Format
Sort by

Send to

Choose Destination

Search results

Items: 1 to 20 of 34

1.

The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable.

Nickerson D, Atalag K, de Bono B, Geiger J, Goble C, Hollmann S, Lonien J, Müller W, Regierer B, Stanford NJ, Golebiewski M, Hunter P.

Interface Focus. 2016 Apr 6;6(2):20150103. doi: 10.1098/rsfs.2015.0103. Review.

PMID:
27051515
2.

Requirements for the formal representation of pathophysiology mechanisms by clinicians.

de Bono B, Helvensteijn M, Kokash N, Martorelli I, Sarwar D, Islam S, Grenon P, Hunter P.

Interface Focus. 2016 Apr 6;6(2):20150099. doi: 10.1098/rsfs.2015.0099.

PMID:
27051514
3.

A physiome interoperability roadmap for personalized drug development.

Thomas S, Wolstencroft K, de Bono B, Hunter PJ.

Interface Focus. 2016 Apr 6;6(2):20150094. doi: 10.1098/rsfs.2015.0094.

PMID:
27051513
4.

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

Hofmann-Apitius M, Ball G, Gebel S, Bagewadi S, de Bono B, Schneider R, Page M, Kodamullil AT, Younesi E, Ebeling C, Tegnér J, Canard L.

Int J Mol Sci. 2015 Dec 7;16(12):29179-206. doi: 10.3390/ijms161226148. Review.

5.

TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.

Radjabova V, Mastroeni P, Skjødt K, Zaccone P, de Bono B, Goodall JC, Chilvers ER, Juss JK, Jones DC, Trowsdale J, Barrow AD.

J Immunol. 2015 Oct 1;195(7):3149-59. doi: 10.4049/jimmunol.1401847. Epub 2015 Aug 26.

6.

The Open Physiology workflow: modeling processes over physiology circuitboards of interoperable tissue units.

de Bono B, Safaei S, Grenon P, Nickerson DP, Alexander S, Helvensteijn M, Kok JN, Kokash N, Wu A, Yu T, Hunter P, Baldock RA.

Front Physiol. 2015 Feb 24;6:24. doi: 10.3389/fphys.2015.00024. eCollection 2015.

7.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SB, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC; BRIDGE Consortium, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HH, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

8.

Biophysical constraints on the evolution of tissue structure and function.

Hunter PJ, de Bono B.

J Physiol. 2014 Jun 1;592(11):2389-401. doi: 10.1113/jphysiol.2014.273235.

9.

A vision and strategy for the virtual physiological human: 2012 update.

Hunter P, Chapman T, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Shublaq N, Skår J, Stroetmann K, Tegner J, Thomas SR, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Interface Focus. 2013 Apr 6;3(2):20130004. doi: 10.1098/rsfs.2013.0004.

10.

HuPSON: the human physiology simulation ontology.

Gündel M, Younesi E, Malhotra A, Wang J, Li H, Zhang B, de Bono B, Mevissen HT, Hofmann-Apitius M.

J Biomed Semantics. 2013 Nov 22;4(1):35. doi: 10.1186/2041-1480-4-35.

11.

Functional tissue units and their primary tissue motifs in multi-scale physiology.

de Bono B, Grenon P, Baldock R, Hunter P.

J Biomed Semantics. 2013 Oct 8;4(1):22. doi: 10.1186/2041-1480-4-22.

12.

Eliciting candidate anatomical routes for protein interactions: a scenario from endocrine physiology.

Grenon P, de Bono B.

BMC Bioinformatics. 2013 Apr 16;14:131. doi: 10.1186/1471-2105-14-131.

13.

Integrating knowledge representation and quantitative modelling in physiology.

de Bono B, Hunter P.

Biotechnol J. 2012 Aug;7(8):958-72. doi: 10.1002/biot.201100304.

PMID:
22887885
14.
15.

An infrastructure for ontology-based information systems in biomedicine: RICORDO case study.

Wimalaratne SM, Grenon P, Hoehndorf R, Gkoutos GV, de Bono B.

Bioinformatics. 2012 Feb 1;28(3):448-50. doi: 10.1093/bioinformatics/btr662. Epub 2011 Nov 29.

16.

The RICORDO approach to semantic interoperability for biomedical data and models: strategy, standards and solutions.

de Bono B, Hoehndorf R, Wimalaratne S, Gkoutos G, Grenon P.

BMC Res Notes. 2011 Aug 30;4:313. doi: 10.1186/1756-0500-4-313.

17.

Integrating systems biology models and biomedical ontologies.

Hoehndorf R, Dumontier M, Gennari JH, Wimalaratne S, de Bono B, Cook DL, Gkoutos GV.

BMC Syst Biol. 2011 Aug 11;5:124. doi: 10.1186/1752-0509-5-124.

18.

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.

Goodall AH, Burns P, Salles I, Macaulay IC, Jones CI, Ardissino D, de Bono B, Bray SL, Deckmyn H, Dudbridge F, Fitzgerald DJ, Garner SF, Gusnanto A, Koch K, Langford C, O'Connor MN, Rice CM, Stemple D, Stephens J, Trip MD, Zwaginga JJ, Samani NJ, Watkins NA, Maguire PB, Ouwehand WH; Bloodomics Consortium.

Blood. 2010 Nov 25;116(22):4646-56. doi: 10.1182/blood-2010-04-280925. Epub 2010 Sep 10.

19.

A vision and strategy for the virtual physiological human in 2010 and beyond.

Hunter P, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Skår J, Tegner J, Randall Thomas S, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Philos Trans A Math Phys Eng Sci. 2010 Jun 13;368(1920):2595-614. doi: 10.1098/rsta.2010.0048.

20.

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, Earthrowl M, Farndale RW, Hoylaerts MF, Koch K, Rankin A, Rice CM, Rogers J, Samani NJ, Steward M, Walker A, Watkins NA, Akkerman JW, Dudbridge F, Goodall AH, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 Aug 13;114(7):1405-16. doi: 10.1182/blood-2009-02-202614. Epub 2009 May 8.

Items per page

Supplemental Content

Loading ...
Write to the Help Desk