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Results: 1 to 20 of 29

1.

The Open Physiology workflow: modeling processes over physiology circuitboards of interoperable tissue units.

de Bono B, Safaei S, Grenon P, Nickerson DP, Alexander S, Helvensteijn M, Kok JN, Kokash N, Wu A, Yu T, Hunter P, Baldock RA.

Front Physiol. 2015 Feb 24;6:24. doi: 10.3389/fphys.2015.00024. eCollection 2015.

2.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SB, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC; BRIDGE Consortium, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HH, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

3.

Biophysical constraints on the evolution of tissue structure and function.

Hunter PJ, de Bono B.

J Physiol. 2014 Jun 1;592(Pt 11):2389-401. doi: 10.1113/jphysiol.2014.273235.

4.

A vision and strategy for the virtual physiological human: 2012 update.

Hunter P, Chapman T, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Shublaq N, Skår J, Stroetmann K, Tegner J, Thomas SR, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Interface Focus. 2013 Apr 6;3(2):20130004. doi: 10.1098/rsfs.2013.0004.

5.

HuPSON: the human physiology simulation ontology.

Gündel M, Younesi E, Malhotra A, Wang J, Li H, Zhang B, de Bono B, Mevissen HT, Hofmann-Apitius M.

J Biomed Semantics. 2013 Nov 22;4(1):35. doi: 10.1186/2041-1480-4-35.

6.

Functional tissue units and their primary tissue motifs in multi-scale physiology.

de Bono B, Grenon P, Baldock R, Hunter P.

J Biomed Semantics. 2013 Oct 8;4(1):22. doi: 10.1186/2041-1480-4-22.

7.

Eliciting candidate anatomical routes for protein interactions: a scenario from endocrine physiology.

Grenon P, de Bono B.

BMC Bioinformatics. 2013 Apr 16;14:131. doi: 10.1186/1471-2105-14-131.

8.

Integrating knowledge representation and quantitative modelling in physiology.

de Bono B, Hunter P.

Biotechnol J. 2012 Aug;7(8):958-72. doi: 10.1002/biot.201100304.

PMID:
22887885
9.
10.

An infrastructure for ontology-based information systems in biomedicine: RICORDO case study.

Wimalaratne SM, Grenon P, Hoehndorf R, Gkoutos GV, de Bono B.

Bioinformatics. 2012 Feb 1;28(3):448-50. doi: 10.1093/bioinformatics/btr662. Epub 2011 Nov 29.

11.

The RICORDO approach to semantic interoperability for biomedical data and models: strategy, standards and solutions.

de Bono B, Hoehndorf R, Wimalaratne S, Gkoutos G, Grenon P.

BMC Res Notes. 2011 Aug 30;4:313. doi: 10.1186/1756-0500-4-313.

12.

Integrating systems biology models and biomedical ontologies.

Hoehndorf R, Dumontier M, Gennari JH, Wimalaratne S, de Bono B, Cook DL, Gkoutos GV.

BMC Syst Biol. 2011 Aug 11;5:124. doi: 10.1186/1752-0509-5-124.

13.

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.

Goodall AH, Burns P, Salles I, Macaulay IC, Jones CI, Ardissino D, de Bono B, Bray SL, Deckmyn H, Dudbridge F, Fitzgerald DJ, Garner SF, Gusnanto A, Koch K, Langford C, O'Connor MN, Rice CM, Stemple D, Stephens J, Trip MD, Zwaginga JJ, Samani NJ, Watkins NA, Maguire PB, Ouwehand WH; Bloodomics Consortium.

Blood. 2010 Nov 25;116(22):4646-56. doi: 10.1182/blood-2010-04-280925. Epub 2010 Sep 10.

14.

A vision and strategy for the virtual physiological human in 2010 and beyond.

Hunter P, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Skår J, Tegner J, Randall Thomas S, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Philos Trans A Math Phys Eng Sci. 2010 Jun 13;368(1920):2595-614. doi: 10.1098/rsta.2010.0048.

15.

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, Earthrowl M, Farndale RW, Hoylaerts MF, Koch K, Rankin A, Rice CM, Rogers J, Samani NJ, Steward M, Walker A, Watkins NA, Akkerman JW, Dudbridge F, Goodall AH, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 Aug 13;114(7):1405-16. doi: 10.1182/blood-2009-02-202614. Epub 2009 May 8.

16.

Comparative genomics indicates the mammalian CD33rSiglec locus evolved by an ancient large-scale inverse duplication and suggests all Siglecs share a common ancestral region.

Cao H, de Bono B, Belov K, Wong ES, Trowsdale J, Barrow AD.

Immunogenetics. 2009 May;61(5):401-17. doi: 10.1007/s00251-009-0372-0. Epub 2009 Apr 1.

PMID:
19337729
17.

A HaemAtlas: characterizing gene expression in differentiated human blood cells.

Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, Hardie DL, Angenent WG, Attwood AP, Ellis PD, Erber W, Foad NS, Garner SF, Isacke CM, Jolley J, Koch K, Macaulay IC, Morley SL, Rendon A, Rice KM, Taylor N, Thijssen-Timmer DC, Tijssen MR, van der Schoot CE, Wernisch L, Winzer T, Dudbridge F, Buckley CD, Langford CF, Teichmann S, Göttgens B, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):e1-9. doi: 10.1182/blood-2008-06-162958. Epub 2009 Feb 19.

18.

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins.

O'Connor MN, Salles II, Cvejic A, Watkins NA, Walker A, Garner SF, Jones CI, Macaulay IC, Steward M, Zwaginga JJ, Bray SL, Dudbridge F, de Bono B, Goodall AH, Deckmyn H, Stemple DL, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):4754-62. doi: 10.1182/blood-2008-06-162693. Epub 2008 Dec 24.

19.

Reactome knowledgebase of human biological pathways and processes.

Matthews L, Gopinath G, Gillespie M, Caudy M, Croft D, de Bono B, Garapati P, Hemish J, Hermjakob H, Jassal B, Kanapin A, Lewis S, Mahajan S, May B, Schmidt E, Vastrik I, Wu G, Birney E, Stein L, D'Eustachio P.

Nucleic Acids Res. 2009 Jan;37(Database issue):D619-22. doi: 10.1093/nar/gkn863. Epub 2008 Nov 3.

20.

SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.

Cao H, Lakner U, de Bono B, Traherne JA, Trowsdale J, Barrow AD.

Eur J Immunol. 2008 Aug;38(8):2303-15. doi: 10.1002/eji.200738078.

PMID:
18629938
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