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    Results: 1 to 20 of 417

    1.

    Pharmacologically Targeting the Primary Defect and Downstream Pathology in Duchenne Muscular Dystrophy.

    Fairclough RJ, Perkins KJ, Davies KE.

    Curr Gene Ther. 2012 May 4. [Epub ahead of print]

    PMID:
    22571500
    [PubMed - as supplied by publisher]
    2.

    Evaluating the links between schizophrenia and sleep and circadian rhythm disruption.

    Pritchett D, Wulff K, Oliver PL, Bannerman DM, Davies KE, Harrison PJ, Peirson SN, Foster RG.

    J Neural Transm. 2012 May 10. [Epub ahead of print]

    PMID:
    22569850
    [PubMed - as supplied by publisher]
    3.

    Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.

    Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS.

    Nature. 2012 Apr 4;484(7394):394-8. doi: 10.1038/nature10980.

    PMID:
    22495301
    [PubMed - in process]
    4.

    Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.

    Goyenvalle A, Babbs A, Wright J, Wilkins V, Powell D, Garcia L, Davies KE.

    Hum Mol Genet. 2012 Jun 1;21(11):2559-71. Epub 2012 Mar 2.

    PMID:
    22388933
    [PubMed - in process]
    Free PMC Article
    5.

    Engineering Multiple U7snRNA Constructs to Induce Single and Multiexon-skipping for Duchenne Muscular Dystrophy.

    Goyenvalle A, Wright J, Babbs A, Wilkins V, Garcia L, Davies KE.

    Mol Ther. 2012 Feb 21. doi: 10.1038/mt.2012.26. [Epub ahead of print]

    PMID:
    22354379
    [PubMed - as supplied by publisher]
    6.

    Disrupted circadian rhythms in a mouse model of schizophrenia.

    Oliver PL, Sobczyk MV, Maywood ES, Edwards B, Lee S, Livieratos A, Oster H, Butler R, Godinho SI, Wulff K, Peirson SN, Fisher SP, Chesham JE, Smith JW, Hastings MH, Davies KE, Foster RG.

    Curr Biol. 2012 Feb 21;22(4):314-9. Epub 2012 Jan 19.

    PMID:
    22264613
    [PubMed - in process]
    7.

    In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.

    Stuckey DJ, Carr CA, Camelliti P, Tyler DJ, Davies KE, Clarke K.

    PLoS One. 2012;7(1):e28569. Epub 2012 Jan 3.

    PMID:
    22235247
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.

    Ravenscroft G, Jackaman C, Sewry CA, McNamara E, Squire SE, Potter AC, Papadimitriou J, Griffiths LM, Bakker AJ, Davies KE, Laing NG, Nowak KJ.

    PLoS One. 2011;6(12):e28699. Epub 2011 Dec 9.

    PMID:
    22174871
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors.

    Tan SC, Carr CA, Yeoh KK, Schofield CJ, Davies KE, Clarke K.

    Mol Biol Rep. 2012 Apr;39(4):4857-67. Epub 2011 Nov 9.

    PMID:
    22065248
    [PubMed - in process]
    Free PMC Article
    10.

    Oxr1 is essential for protection against oxidative stress-induced neurodegeneration.

    Oliver PL, Finelli MJ, Edwards B, Bitoun E, Butts DL, Becker EB, Cheeseman MT, Davies B, Davies KE.

    PLoS Genet. 2011 Oct;7(10):e1002338. Epub 2011 Oct 20.

    PMID:
    22028674
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Progress in therapy for Duchenne muscular dystrophy.

    Fairclough RJ, Bareja A, Davies KE.

    Exp Physiol. 2011 Nov;96(11):1101-13. Epub 2011 Jul 31. Review.

    PMID:
    21804140
    [PubMed - indexed for MEDLINE]
    12.

    Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy.

    Goyenvalle A, Davies KE.

    Skelet Muscle. 2011 Feb 9;1(1):8.

    PMID:
    21798085
    [PubMed]
    Free PMC Article
    13.

    Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

    Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, Ragoussis J, Davies KE, Geschwind DH, Fisher SE.

    PLoS Genet. 2011 Jul;7(7):e1002145. Epub 2011 Jul 7.

    PMID:
    21765815
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.

    Tinsley JM, Fairclough RJ, Storer R, Wilkes FJ, Potter AC, Squire SE, Powell DS, Cozzoli A, Capogrosso RF, Lambert A, Wilson FX, Wren SP, De Luca A, Davies KE.

    PLoS One. 2011 May 6;6(5):e19189.

    PMID:
    21573153
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.

    Pichavant C, Aartsma-Rus A, Clemens PR, Davies KE, Dickson G, Takeda S, Wilton SD, Wolff JA, Wooddell CI, Xiao X, Tremblay JP.

    Mol Ther. 2011 May;19(5):830-40. Epub 2011 Apr 5. Review.

    PMID:
    21468001
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.

    Chancellor DR, Davies KE, De Moor O, Dorgan CR, Johnson PD, Lambert AG, Lawrence D, Lecci C, Maillol C, Middleton PJ, Nugent G, Poignant SD, Potter AC, Price PD, Pye RJ, Storer R, Tinsley JM, van Well R, Vickers R, Vile J, Wilkes FJ, Wilson FX, Wren SP, Wynne GM.

    J Med Chem. 2011 May 12;54(9):3241-50. Epub 2011 Apr 15.

    PMID:
    21456623
    [PubMed - indexed for MEDLINE]
    17.

    Therapeutic approaches to muscular dystrophy.

    Goyenvalle A, Seto JT, Davies KE, Chamberlain J.

    Hum Mol Genet. 2011 Apr 15;20(R1):R69-78. Epub 2011 Mar 24. Review.

    PMID:
    21436158
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Candidate screening of the TRPC3 gene in cerebellar ataxia.

    Becker EB, Fogel BL, Rajakulendran S, Dulneva A, Hanna MG, Perlman SL, Geschwind DH, Davies KE.

    Cerebellum. 2011 Jun;10(2):296-9.

    PMID:
    21321808
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies.

    Ravenscroft G, Jackaman C, Bringans S, Papadimitriou JM, Griffiths LM, McNamara E, Bakker AJ, Davies KE, Laing NG, Nowak KJ.

    Brain. 2011 Apr;134(Pt 4):1101-15. Epub 2011 Feb 8.

    PMID:
    21303860
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Engineering exon-skipping vectors expressing U7 snRNA constructs for Duchenne muscular dystrophy gene therapy.

    Goyenvalle A, Davies KE.

    Methods Mol Biol. 2011;709:179-96.

    PMID:
    21194028
    [PubMed - indexed for MEDLINE]

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