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Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST).
Deswal A, Petersen NJ, Feldman AM, Young JB, White BG, Mann DL. Deswal A, et al. Circulation. 2001 Apr 24;103(16):2055-9. doi: 10.1161/01.cir.103.16.2055. Circulation. 2001. PMID: 11319194
BACKGROUND: Previous reports have shown that elevated circulating levels of cytokines and/or cytokine receptors predict adverse outcomes in patients with heart failure. ...CONCLUSIONS: Cytokines and cytokine receptors are in …
BACKGROUND: Previous reports have shown that elevated circulating levels of cytokines and/or cytokine receptors predict …
Effects of vesnarinone on peripheral circulating levels of cytokines and cytokine receptors in patients with heart failure: a report from the Vesnarinone Trial.
Deswal A, Petersen NJ, Feldman AM, White BG, Mann DL. Deswal A, et al. Chest. 2001 Aug;120(2):453-9. doi: 10.1378/chest.120.2.453. Chest. 2001. PMID: 11502643 Clinical Trial.
STUDY OBJECTIVES: Proinflammatory cytokines may contribute to disease progression in heart failure by virtue of the direct toxic effects that these molecules exert on the heart and the circulation. ...Therefore, we examined the effects of vesnarinon …
STUDY OBJECTIVES: Proinflammatory cytokines may contribute to disease progression in heart failure by virtue of the dir …
New predictive models of heart failure mortality using time-series measurements and ensemble models.
Subramanian D, Subramanian V, Deswal A, Mann DL. Subramanian D, et al. Circ Heart Fail. 2011 Jul;4(4):456-62. doi: 10.1161/CIRCHEARTFAILURE.110.958496. Epub 2011 May 11. Circ Heart Fail. 2011. PMID: 21562057 Free PMC article.
Despite this, most multivariate predictive models for heart failure mortality have predictive accuracies characterized by a C-statistic (area under the receiver operating curve) of 0.74. ...CONCLUSIONS: Significant gains in accuracy of one year mortality prediction …
Despite this, most multivariate predictive models for heart failure mortality have predictive accuracies characterized by a C- …
Vesnarinone: a potential cytokine inhibitor.
Sasayama S, Matsumori A. Sasayama S, et al. J Card Fail. 1996 Sep;2(3):251-8. doi: 10.1016/s1071-9164(96)80048-0. J Card Fail. 1996. PMID: 8891863 Review.
There is a growing body of evidence that cytokines may play an important role in the pathogenesis of heart failure, and the intriguing possibility has been postulated that anticytokine therapy may favorably alter the clinical outcome of heart failur …
There is a growing body of evidence that cytokines may play an important role in the pathogenesis of heart failure, and …