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Page 1
Synthesis of Urease Inhibitory 2, 4-bis (4-cyanobenzyl)glycoluril using Sandmeyer Reaction and Density Functional Theory Investigation.
Yawer MA, Bano S, Saleem M, Yawer A, Hussain R, Imran M, Irfan A, Rauf A, Abu-Izneid T. Yawer MA, et al. Curr Org Synth. 2021 Oct 26;18(6):592-597. doi: 10.2174/1570179418666210113162909. Curr Org Synth. 2021. PMID: 33441077
AIMS: The aim of the present research was to synthesize glycoluril derivative 2,4-Bis(4- cyanobenzyl)glycoluril through a convergent scheme. BACKGROUND: For this purpose, Sandmeyer reaction procedure was employed for the synthesis of said compound. ...CONCLUSION: We have s …
AIMS: The aim of the present research was to synthesize glycoluril derivative 2,4-Bis(4- cyanobenzyl)glycoluril through a convergent …
meta-Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, alpha-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties.
Türker F, Barut Celepci D, Aktaş A, Taslimi P, Gök Y, Aygün M, Gülçin İ. Türker F, et al. Arch Pharm (Weinheim). 2018 Jul;351(7):e1800029. doi: 10.1002/ardp.201800029. Epub 2018 May 22. Arch Pharm (Weinheim). 2018. PMID: 29963738
meta-Cyanobenzyl-substituted N-heterocyclic carbene (NHC) precursors were synthesized by the reaction of a series of N-(alkyl)benzimidazolium with 3-bromomethyl-benzonitrile. ...
meta-Cyanobenzyl-substituted N-heterocyclic carbene (NHC) precursors were synthesized by the reaction of a series of N-(alkyl)benzimi …
Synthesis and potent inhibitory activities of carboxybenzyl-substituted 8-(3-(R)-aminopiperidin-1-yl)-7-(2-chloro/cyanobenzyl)-3-methyl-3,7-dihydro-purine-2,6-diones as dipeptidyl peptidase IV (DPP-IV) inhibitors.
Mo DW, Dong S, Sun H, Chen JS, Pang JX, Xi BM, Chen WH. Mo DW, et al. Bioorg Med Chem Lett. 2015 May 1;25(9):1872-5. doi: 10.1016/j.bmcl.2015.03.048. Epub 2015 Mar 24. Bioorg Med Chem Lett. 2015. PMID: 25838146
Fourteen 3-methyl-3,7-dihydro-purine-2,6-dione derivatives 1-14 bearing carboxybenzyl and 2-chloro/cyanobenzyl groups at the N-1 and N-7 positions, respectively, were synthesized as dipeptidyl peptidase IV (DPP-IV) inhibitors. ...
Fourteen 3-methyl-3,7-dihydro-purine-2,6-dione derivatives 1-14 bearing carboxybenzyl and 2-chloro/cyanobenzyl groups at the N-1 and …
The intriguing dual-directing effect of 2-cyanobenzyl ether for a highly stereospecific glycosylation reaction.
Le Mai Hoang K, Liu XW. Le Mai Hoang K, et al. Nat Commun. 2014 Oct 3;5:5051. doi: 10.1038/ncomms6051. Nat Commun. 2014. PMID: 25277946 Free article.
In this report, the unification of solvent assistance and neighbouring group participation concepts have led us to the use of 2-cyanobenzyl ether as the dual-directing auxiliary for stereospecific construction of alpha- and beta-glycosidic bonds from a single starting mate …
In this report, the unification of solvent assistance and neighbouring group participation concepts have led us to the use of 2-cyanobenz …
Prediction of Biological Activities, Structural Investigation and Theoretical Studies of meta-cyanobenzyl Substituted Benzimidazolium Salts.
Celepci DB, AktaĹź AN. Celepci DB, et al. Acta Chim Slov. 2020 Sep;67(3):830-841. Acta Chim Slov. 2020. PMID: 33533414
The structuralproperties of meta-cyanobenzyl substituted N-heterocyclic carbene (NHC) precursors were investigated theoretically. ...
The structuralproperties of meta-cyanobenzyl substituted N-heterocyclic carbene (NHC) precursors were investigated theoretically. ...
Novel benzyl-substituted N-heterocyclic carbene-silver acetate complexes: synthesis, cytotoxicity and antibacterial studies.
Patil S, Deally A, Gleeson B, Müller-Bunz H, Paradisi F, Tacke M. Patil S, et al. Metallomics. 2011 Jan;3(1):74-88. doi: 10.1039/c0mt00034e. Epub 2010 Dec 6. Metallomics. 2011. PMID: 21135954
From the reaction of 1-methylimidazole (1a), 4,5-dichloro-1H-imidazole (1b(I)) and 1-methylbenzimidazole (1c) with p-cyanobenzyl bromide (2a), non-symmetrically substituted N-heterocyclic carbene (NHC) [(3a-c)] precursors, 5,6-dimethyl-1H-benzimidazole (1d) and 4,5-dipheny …
From the reaction of 1-methylimidazole (1a), 4,5-dichloro-1H-imidazole (1b(I)) and 1-methylbenzimidazole (1c) with p-cyanobenzyl brom …
79 results