Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 4
1967 1
1969 1
1970 2
1971 2
1972 2
1973 1
1974 1
1975 5
1976 7
1977 9
1978 4
1979 5
1980 6
1981 3
1982 5
1983 8
1984 7
1985 7
1986 9
1987 6
1988 10
1989 8
1990 16
1991 11
1992 19
1993 23
1994 16
1995 33
1996 30
1997 40
1998 22
1999 22
2000 26
2001 48
2002 54
2003 48
2004 68
2005 70
2006 69
2007 75
2008 76
2009 77
2010 97
2011 108
2012 132
2013 144
2014 147
2015 149
2016 161
2017 131
2018 163
2019 175
2020 158
2021 172
2022 183
2023 176
2024 80

Text availability

Article attribute

Article type

Publication date

Search Results

2,806 results

Results by year

Filters applied: . Clear all
Page 1
Epigenetic clock: A promising biomarker and practical tool in aging.
Duan R, Fu Q, Sun Y, Li Q. Duan R, et al. Ageing Res Rev. 2022 Nov;81:101743. doi: 10.1016/j.arr.2022.101743. Epub 2022 Oct 4. Ageing Res Rev. 2022. PMID: 36206857 Review.
In this burgeoning scientific field, various kinds of epigenetic clocks continue to emerge, including Horvath's clock, Hannum's clock, DNA PhenoAge, and DNA GrimAge. We hereby present the most classic epigenetic clocks, as well as their differences. Co …
In this burgeoning scientific field, various kinds of epigenetic clocks continue to emerge, including Horvath's clock, Hannum' …
Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.
Qu M, Zhang G, Qu H, Vu A, Wu R, Tsukamoto H, Jia Z, Huang W, Lenz HJ, Rich JN, Kay SA. Qu M, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2214829120. doi: 10.1073/pnas.2214829120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595671 Free PMC article.
Collectively, our results suggest that the circadian clock regulators BMAL1 and CLOCK promote HCC cell proliferation by controlling Wee1 and p21 levels, thereby preventing apoptosis and cell cycle arrest. Our findings shed light on cellular impact of the clock …
Collectively, our results suggest that the circadian clock regulators BMAL1 and CLOCK promote HCC cell proliferation by contro …
Time-restricted feeding mitigates obesity through adipocyte thermogenesis.
Hepler C, Weidemann BJ, Waldeck NJ, Marcheva B, Cedernaes J, Thorne AK, Kobayashi Y, Nozawa R, Newman MV, Gao P, Shao M, Ramsey KM, Gupta RK, Bass J. Hepler C, et al. Science. 2022 Oct 21;378(6617):276-284. doi: 10.1126/science.abl8007. Epub 2022 Oct 20. Science. 2022. PMID: 36264811 Free PMC article.
Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity. Conversely, restricting feeding to the active period mitigates metabolic syndrome through mechanisms that remain unknown. ...Circadian control of adipocyte …
Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity. Conversely, res …
Role of High Energy Breakfast "Big Breakfast Diet" in Clock Gene Regulation of Postprandial Hyperglycemia and Weight Loss in Type 2 Diabetes.
Jakubowicz D, Wainstein J, Tsameret S, Landau Z. Jakubowicz D, et al. Nutrients. 2021 May 5;13(5):1558. doi: 10.3390/nu13051558. Nutrients. 2021. PMID: 34063109 Free PMC article. Review.
T2D and meal timing schedule not synchronized with the circadian clock (i.e., skipping breakfast) are associated with disrupted clock gene expression and is linked to PPHG. ...Therefore, resetting clock gene expression through a diet intervention consisting o …
T2D and meal timing schedule not synchronized with the circadian clock (i.e., skipping breakfast) are associated with disrupted cl …
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Wang Z, Su G, Dai Z, Meng M, Zhang H, Fan F, Liu Z, Zhang L, Weygant N, He F, Fang N, Zhang L, Cheng Q. Wang Z, et al. Cell Prolif. 2021 Mar;54(3):e12988. doi: 10.1111/cpr.12988. Epub 2021 Jan 13. Cell Prolif. 2021. PMID: 33442944 Free PMC article.
OBJECTIVES: Circadian rhythm controls complicated physiological activities in organisms. Circadian clock genes have been related to tumour progression, but its role in glioma is unknown. Therefore, we explored the relationship between dysregulated circadian clock …
OBJECTIVES: Circadian rhythm controls complicated physiological activities in organisms. Circadian clock genes have been relat …
Social jetlag and obesity.
Roenneberg T, Allebrandt KV, Merrow M, Vetter C. Roenneberg T, et al. Curr Biol. 2012 May 22;22(10):939-43. doi: 10.1016/j.cub.2012.03.038. Epub 2012 May 10. Curr Biol. 2012. PMID: 22578422 Free article.
Social jetlag quantifies the discrepancy that often arises between circadian and social clocks, which results in chronic sleep loss. The circadian clock also regulates energy homeostasis, and its disruption-as with social jetlag-may contribute to weight-related path …
Social jetlag quantifies the discrepancy that often arises between circadian and social clocks, which results in chronic sleep loss. …
The importance of the circadian system & sleep for bone health.
Swanson CM, Kohrt WM, Buxton OM, Everson CA, Wright KP Jr, Orwoll ES, Shea SA. Swanson CM, et al. Metabolism. 2018 Jul;84:28-43. doi: 10.1016/j.metabol.2017.12.002. Epub 2017 Dec 9. Metabolism. 2018. PMID: 29229227 Free PMC article. Review.
This review examines the diurnal variation of bone turnover markers (BTMs) and the importance of circadian clock genes in regulating bone mass. In addition, this review explores the evidence for a link between shift work (and its associated disturbances in sleep duration/q …
This review examines the diurnal variation of bone turnover markers (BTMs) and the importance of circadian clock genes in regulating …
Circadian clock and cell cycle: Cancer and chronotherapy.
Yao J, He C, Zhao W, Hu N, Long D. Yao J, et al. Acta Histochem. 2021 Dec;123(8):151816. doi: 10.1016/j.acthis.2021.151816. Epub 2021 Nov 17. Acta Histochem. 2021. PMID: 34800857 Review.
However, the relationship between the circadian clock and the cell cycle is extremely complicated. This review summarizes the possible connection between the circadian clock and the cell cycle. In addition, the review provides evidence of the influence of the …
However, the relationship between the circadian clock and the cell cycle is extremely complicated. This review summarizes the …
Clock desynchronisation: why and how?
Ouitou Y. Ouitou Y. Bull Acad Natl Med. 2015 Oct;199(7):1073-1080. Bull Acad Natl Med. 2015. PMID: 29879329 Review. English, French.
The internal clock located in the suprachiasmatic nuclei of the anterior hypothalamus is controlled by external (environment and social life) and genetic factors. Desynchronisation of the organism occurs when the clock does no longer work in harmony with the environ …
The internal clock located in the suprachiasmatic nuclei of the anterior hypothalamus is controlled by external (environment and soci …
The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.
Ono M, Ando H, Daikoku T, Fujiwara T, Mieda M, Mizumoto Y, Iizuka T, Kagami K, Hosono T, Nomura S, Toyoda N, Sekizuka-Kagami N, Maida Y, Kuji N, Nishi H, Fujiwara H. Ono M, et al. Int J Mol Sci. 2023 Jan 12;24(2):1545. doi: 10.3390/ijms24021545. Int J Mol Sci. 2023. PMID: 36675058 Free PMC article. Review.
The circadian rhythm, which is necessary for reproduction, is controlled by clock genes. In the mouse uterus, the oscillation of the circadian clock gene has been observed. ...Furthermore, it was shown that time-restricted feeding controlled the uterine clock …
The circadian rhythm, which is necessary for reproduction, is controlled by clock genes. In the mouse uterus, the oscillation of the …
2,806 results