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Year Number of Results
1983 1
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1992 2
1993 1
1994 3
1995 4
1996 3
1997 1
1998 2
2002 1
2003 2
2004 3
2009 1
2023 1
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27 results

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Page 1
Effects of cocaine, benzoylecgonine, and cocaine metabolites in cannulated pressurized fetal sheep cerebral arteries.
Schreiber MD, Madden JA, Covert RF, Torgerson LJ. Schreiber MD, et al. J Appl Physiol (1985). 1994 Aug;77(2):834-9. doi: 10.1152/jappl.1994.77.2.834. J Appl Physiol (1985). 1994. PMID: 8002536
To determine the effect of cocaine on the fetal neurovasculature, we studied the in vitro response of fetal sheep cerebral arteries to cocaine and cocaine metabolites. ...Benzoylecgonine (> 10(-10) M) also caused concentration-dependent constrict …
To determine the effect of cocaine on the fetal neurovasculature, we studied the in vitro response of fetal sheep cerebral arteries t …
Cocaine and its metabolites constrict cerebral arterioles in newborn pigs.
Kurth CD, Monitto C, Albuquerque ML, Feuer P, Anday E, Shaw L. Kurth CD, et al. J Pharmacol Exp Ther. 1993 May;265(2):587-91. J Pharmacol Exp Ther. 1993. PMID: 8496809
Cerebral vasoconstriction induced by topically applied norepinephrine was enhanced by cocaine, norcocaine and cocaethylene, but not by the other three metabolites. Topical application of phentolamine failed to block vasoconstriction elicited by coca …
Cerebral vasoconstriction induced by topically applied norepinephrine was enhanced by cocaine, norcocaine and cocaethylene, bu …
Effect of cocaine and cocaine metabolites on cerebral arteries in vitro.
Madden JA, Powers RH. Madden JA, et al. Life Sci. 1990;47(13):1109-14. doi: 10.1016/0024-3205(90)90169-r. Life Sci. 1990. PMID: 2233129
The role of cocaine metabolites in vasoconstriction attributed to cocaine has not been reported. We evaluated the contractile ability of cocaine and its major metabolites in isolated cat cerebral arteries. ...
The role of cocaine metabolites in vasoconstriction attributed to cocaine has not been reported. We evaluated th …
Maternal and transplacental effects of cocaine.
Woods JR. Woods JR. Ann N Y Acad Sci. 1998 Jun 21;846:1-11. Ann N Y Acad Sci. 1998. PMID: 9668393 Review.
Pregnancy is a dynamic process, and maternal as well as fetal risks from cocaine use in pregnancy may differ as pregnancy progresses. Three areas of biology offer opportunities for reevaluating cocaine's effects in pregnancy: (1) Maternal cardiovascular and n …
Pregnancy is a dynamic process, and maternal as well as fetal risks from cocaine use in pregnancy may differ as pregnancy progresses. …
Cocaine and cardiovascular toxicity.
Schindler CW. Schindler CW. Addict Biol. 1996;1(1):31-47. doi: 10.1080/1355621961000124676. Addict Biol. 1996. PMID: 12893485
Both these effects appear to be mediated by cocaine's local anesthetic action. The effects of cocaine mediated by the sympathetic nervous system are greatly reduced in anesthetized animals. ...In addition to the effects of cocaine alone, the metabol …
Both these effects appear to be mediated by cocaine's local anesthetic action. The effects of cocaine mediated by the s …
Episodic Cocaine Use as a Cause of Venous Thromboembolism and Acute Liver Injury.
Patel KH, Thomas KC, Stacey SK. Patel KH, et al. Am J Case Rep. 2023 Oct 24;24:e941360. doi: 10.12659/AJCR.941360. Am J Case Rep. 2023. PMID: 37872733 Free PMC article.
CONCLUSIONS When investigating the cause of venous thromboembolism and transaminitis, evaluating cocaine use via patient history or laboratory analysis of cocaine and its metabolites should be considered. Cocaine is known to cause vasoconstriction …
CONCLUSIONS When investigating the cause of venous thromboembolism and transaminitis, evaluating cocaine use via patient history or l …
Maternal and Transplacental Effects of Cocaine.
Woods JR Jr. Woods JR Jr. Ann N Y Acad Sci. 1998 Jun;846(1):1-11. doi: 10.1111/j.1749-6632.1998.tb09722.x. Ann N Y Acad Sci. 1998. PMID: 29087546
Pregnancy is a dynamic process, and maternal as well as fetal risks from cocaine use in pregnancy may differ as pregnancy progresses. Three areas of biology offer opportunities for reevaluating cocaine's effects in pregnancy: (1) Maternal cardiovascular and n …
Pregnancy is a dynamic process, and maternal as well as fetal risks from cocaine use in pregnancy may differ as pregnancy progresses. …
Effects of ethanol on cocaine metabolism: formation of cocaethylene and norcocaethylene.
Dean RA, Harper ET, Dumaual N, Stoeckel DA, Bosron WF. Dean RA, et al. Toxicol Appl Pharmacol. 1992 Nov;117(1):1-8. doi: 10.1016/0041-008x(92)90210-j. Toxicol Appl Pharmacol. 1992. PMID: 1440602
The increased morbidity and hepatotoxicity seen with acute combined administration of cocaine and ethanol may be due to the formation of the toxic ethylated and N-demethylated metabolites of cocaine. ...The most important consequence of ethanol-induced inhibi …
The increased morbidity and hepatotoxicity seen with acute combined administration of cocaine and ethanol may be due to the formation …
Potential mechanisms of cocaine-induced developmental neurotoxicity: a minireview.
Olsen GD. Olsen GD. Neurotoxicology. 1995 Spring;16(1):159-67. Neurotoxicology. 1995. PMID: 7603637 Review.
There is great concern about the health effects of cocaine use during pregnancy. Cocaine alters maternal physiology and crosses the placenta to interact with fetal tissues including the brain. ...Animal studies, which allow quantitation of drug exposure and reductio …
There is great concern about the health effects of cocaine use during pregnancy. Cocaine alters maternal physiology and crosse …
Cocaine-induced endothelin-1-dependent spasm in rabbit basilar artery in vivo.
Fandino J, Sherman JD, Zuccarello M, Rapoport RM. Fandino J, et al. J Cardiovasc Pharmacol. 2003 Feb;41(2):158-61. doi: 10.1097/00005344-200302000-00002. J Cardiovasc Pharmacol. 2003. PMID: 12548074
Although cocaine-induced constriction of cerebral vessels may play an important negative role in the pathogenesis of cocaine-related stroke, the mechanism underlying the vasospasm remains unclear. ...Cerebral spinal fluid levels of cocaine and benzoyle …
Although cocaine-induced constriction of cerebral vessels may play an important negative role in the pathogenesis of cocain …
27 results