Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 7
1973 4
1974 4
1975 8
1976 7
1977 8
1978 16
1979 14
1980 6
1981 25
1982 17
1983 14
1984 15
1985 21
1986 7
1987 18
1988 16
1989 13
1990 16
1991 11
1992 11
1993 9
1994 12
1995 15
1996 11
1997 5
1998 6
1999 7
2000 6
2001 6
2002 5
2003 9
2004 8
2005 5
2006 12
2007 9
2008 7
2009 2
2010 8
2011 7
2012 6
2013 5
2014 3
2015 5
2016 9
2017 8
2018 11
2019 10
2020 21
2021 26
2022 23
2023 28
2024 16

Text availability

Article attribute

Article type

Publication date

Search Results

552 results

Results by year

Filters applied: . Clear all
Page 1
Clemastine.
[No authors listed] [No authors listed] 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000667 Free Books & Documents. Review.
Small occasional doses of clemastine are acceptable during breastfeeding. Larger doses or more prolonged use may cause drowsiness and other effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or befo …
Small occasional doses of clemastine are acceptable during breastfeeding. Larger doses or more prolonged use may cause drowsiness and …
Drug repurposing: Clemastine fumarate and neurodegeneration.
Zhu J, Ma R, Li G. Zhu J, et al. Biomed Pharmacother. 2023 Jan;157:113904. doi: 10.1016/j.biopha.2022.113904. Epub 2022 Nov 9. Biomed Pharmacother. 2023. PMID: 36370521 Free article. Review.
Surprisingly, fumarate salt also has similar effect. Hence, whether clemastine fumarate would make a protective impact on neurodegenerative diseases and what contribution fumarate probably makes are intriguing to us. In this review, we summarize the potential mechanism sur …
Surprisingly, fumarate salt also has similar effect. Hence, whether clemastine fumarate would make a protective impact on neurodegene …
Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.
Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR. Green AJ, et al. Lancet. 2017 Dec 2;390(10111):2481-2489. doi: 10.1016/S0140-6736(17)32346-2. Epub 2017 Oct 10. Lancet. 2017. PMID: 29029896 Clinical Trial.
We aimed to analyse the efficacy and safety of clemastine fumarate as a treatment for patients with multiple sclerosis. ...Clemastine fumarate treatment was associated with fatigue, but no serious adverse events were reported. ...
We aimed to analyse the efficacy and safety of clemastine fumarate as a treatment for patients with multiple sclerosis. ...Clemast …
Clemastine.
[No authors listed] [No authors listed] 2017 Jan 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jan 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644019 Free Books & Documents. Review.
Clemastine is a first generation antihistamine that is used for symptoms of allergic rhinitis and the common cold. Clemastine has not been linked to instances of clinically apparent acute liver injury....
Clemastine is a first generation antihistamine that is used for symptoms of allergic rhinitis and the common cold. Clemastine …
Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury.
Myatich A, Haque A, Sole C, Banik NL. Myatich A, et al. Neural Regen Res. 2023 May;18(5):940-946. doi: 10.4103/1673-5374.355749. Neural Regen Res. 2023. PMID: 36254972 Free PMC article. Review.
While clemastine can aid not only in the remyelination and preservation of myelin sheath integrity, it also protects neurons. ...This review discusses the pathophysiology of spinal cord injury, and the role of clemastine in the protection of neurons, myelin, and axo …
While clemastine can aid not only in the remyelination and preservation of myelin sheath integrity, it also protects neurons. ...This …
Insights on therapeutic potential of clemastine in neurological disorders.
Jiang S, Wang X, Cao T, Kang R, Huang L. Jiang S, et al. Front Mol Neurosci. 2023 Sep 28;16:1279985. doi: 10.3389/fnmol.2023.1279985. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37840769 Free PMC article. Review.
Clemastine, a Food and Drug Administration (FDA)-approved compound, is recognized as a first-generation, widely available antihistamine that reduces histamine-induced symptoms. Evidence has confirmed that clemastine can transport across the blood-brain barrier and a …
Clemastine, a Food and Drug Administration (FDA)-approved compound, is recognized as a first-generation, widely available antihistami …
Clemastine Induces an Impairment in Developmental Myelination.
Palma A, Chara JC, Montilla A, Otxoa-de-Amezaga A, Ruíz-Jaén F, Planas AM, Matute C, Pérez-Samartín A, Domercq M. Palma A, et al. Front Cell Dev Biol. 2022 Mar 17;10:841548. doi: 10.3389/fcell.2022.841548. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35372341 Free PMC article.
However, its role in myelination during development is unknown. We showed that clemastine treatment during development increased oligodendrocyte differentiation in both white and gray matter. ...Importantly, the population of CD11c(+) microglia cells, necessary for myelina …
However, its role in myelination during development is unknown. We showed that clemastine treatment during development increased olig …
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Zhu J, Jiang X, Chang Y, Wu Y, Sun S, Wang C, Zheng S, Wang M, Yao Y, Li G, Ma R. Zhu J, et al. Int Immunopharmacol. 2023 Oct;123:110649. doi: 10.1016/j.intimp.2023.110649. Epub 2023 Jul 24. Int Immunopharmacol. 2023. PMID: 37494840
Based on these findings, we investigated the effect of clemastine fumarate in hTau mice, a different Alzheimer's disease model characterized by overexpression of human Tau protein. ...Notably, after administration of chloroquine, levels of Tau protein were significantly in …
Based on these findings, we investigated the effect of clemastine fumarate in hTau mice, a different Alzheimer's disease model charac …
Repurposing Clemastine to Target Glioblastoma Cell Stemness.
Sun MA, Yang R, Liu H, Wang W, Song X, Hu B, Reynolds N, Roso K, Chen LH, Greer PK, Keir ST, McLendon RE, Cheng SY, Bigner DD, Ashley DM, Pirozzi CJ, He Y. Sun MA, et al. Cancers (Basel). 2023 Sep 18;15(18):4619. doi: 10.3390/cancers15184619. Cancers (Basel). 2023. PMID: 37760589 Free PMC article.
These effects on BTICs were accompanied by altered gene expression profiling indicative of their more differentiated states, resonating with the activity of clemastine in promoting the differentiation of normal oligodendrocyte progenitor cells (OPCs) into mature oligodendr …
These effects on BTICs were accompanied by altered gene expression profiling indicative of their more differentiated states, resonating with …
Clemastine Promotes Differentiation of Oligodendrocyte Progenitor Cells Through the Activation of ERK1/2 via Muscarinic Receptors After Spinal Cord Injury.
Tong LY, Deng YB, Du WH, Zhou WZ, Liao XY, Jiang X. Tong LY, et al. Front Pharmacol. 2022 Jul 5;13:914153. doi: 10.3389/fphar.2022.914153. eCollection 2022. Front Pharmacol. 2022. PMID: 35865954 Free PMC article.
The significant effect of clemastine on encouraging OPC differentiation was revealed at 14 dpi rather than 7 dpi. ...Moreover, the impact of clemastine on modulating the level of p-ERK 1/2 was restricted following cevimeline pre-injecting, which provides further evi …
The significant effect of clemastine on encouraging OPC differentiation was revealed at 14 dpi rather than 7 dpi. ...Moreover, the im …
552 results

Searches related to "clemastine"