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Results: 1 to 20 of 35

1.

Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain.

Beckel JM, Argall AJ, Lim JC, Xia J, Lu W, Coffey EE, Macarak EJ, Shahidullah M, Delamere NA, Zode GS, Sheffield VC, Shestopalov VI, Laties AM, Mitchell CH.

Glia. 2014 Sep;62(9):1486-501. doi: 10.1002/glia.22695. Epub 2014 May 19.

PMID:
24839011
[PubMed - in process]
2.

Autophagy in the eye: Implications for ocular cell health.

Frost LS, Mitchell CH, Boesze-Battaglia K.

Exp Eye Res. 2014 Jul;124C:56-66. doi: 10.1016/j.exer.2014.04.010. Epub 2014 May 6. Review.

PMID:
24810222
[PubMed - as supplied by publisher]
3.

Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells.

Guha S, Liu J, Baltazar G, Laties AM, Mitchell CH.

Adv Exp Med Biol. 2014;801:105-11. doi: 10.1007/978-1-4614-3209-8_14.

PMID:
24664687
[PubMed - in process]
4.

From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma.

Kri┼żaj D, Ryskamp DA, Tian N, Tezel G, Mitchell CH, Slepak VZ, Shestopalov VI.

Curr Eye Res. 2014 Feb;39(2):105-19. doi: 10.3109/02713683.2013.836541. Epub 2013 Oct 21.

PMID:
24144321
[PubMed - in process]
5.

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.

Guha S, Baltazar GC, Coffey EE, Tu LA, Lim JC, Beckel JM, Patel S, Eysteinsson T, Lu W, O'Brien-Jenkins A, Laties AM, Mitchell CH.

FASEB J. 2013 Nov;27(11):4500-9. doi: 10.1096/fj.13-236166. Epub 2013 Aug 20.

PMID:
23964074
[PubMed - indexed for MEDLINE]
6.

Loss of melanoregulin (MREG) enhances cathepsin-D secretion by the retinal pigment epithelium.

Frost LS, Lopes VS, Stefano FP, Bragin A, Williams DS, Mitchell CH, Boesze-Battaglia K.

Vis Neurosci. 2013 May;30(3):55-64. doi: 10.1017/S0952523813000096. Epub 2013 Apr 23.

PMID:
23611523
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells.

Baltazar GC, Guha S, Lu W, Lim J, Boesze-Battaglia K, Laties AM, Tyagi P, Kompella UB, Mitchell CH.

PLoS One. 2012;7(12):e49635. doi: 10.1371/journal.pone.0049635. Epub 2012 Dec 18.

PMID:
23272048
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.

Guha S, Baltazar GC, Tu LA, Liu J, Lim JC, Lu W, Argall A, Boesze-Battaglia K, Laties AM, Mitchell CH.

J Neurochem. 2012 Aug;122(4):823-33. doi: 10.1111/j.1471-4159.2012.07804.x. Epub 2012 Jun 27.

PMID:
22639870
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.

Liu J, Lu W, Guha S, Baltazar GC, Coffey EE, Laties AM, Rubenstein RC, Reenstra WW, Mitchell CH.

Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C160-9. doi: 10.1152/ajpcell.00278.2011. Epub 2012 May 9.

PMID:
22572847
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors.

Xia J, Lim JC, Lu W, Beckel JM, Macarak EJ, Laties AM, Mitchell CH.

J Physiol. 2012 May 1;590(Pt 10):2285-304. doi: 10.1113/jphysiol.2012.227983. Epub 2012 Mar 12.

PMID:
22411013
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma.

Li A, Zhang X, Zheng D, Ge J, Laties AM, Mitchell CH.

Exp Eye Res. 2011 Oct;93(4):528-33. doi: 10.1016/j.exer.2011.06.020. Epub 2011 Jul 2.

PMID:
21745471
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow.

Li A, Leung CT, Peterson-Yantorno K, Stamer WD, Mitchell CH, Civan MM.

J Cell Physiol. 2012 Jan;227(1):172-82. doi: 10.1002/jcp.22715.

PMID:
21381023
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow.

Li A, Leung CT, Peterson-Yantorno K, Mitchell CH, Civan MM.

Am J Physiol Cell Physiol. 2010 Dec;299(6):C1308-17. doi: 10.1152/ajpcell.00333.2010. Epub 2010 Oct 6.

PMID:
20926783
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Superior calcium homeostasis of extraocular muscles.

Zeiger U, Mitchell CH, Khurana TS.

Exp Eye Res. 2010 Nov;91(5):613-22. doi: 10.1016/j.exer.2010.07.019. Epub 2010 Aug 7.

PMID:
20696159
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo.

Hu H, Lu W, Zhang M, Zhang X, Argall AJ, Patel S, Lee GE, Kim YC, Jacobson KA, Laties AM, Mitchell CH.

Exp Eye Res. 2010 Sep;91(3):425-32. doi: 10.1016/j.exer.2010.06.017. Epub 2010 Jul 1.

PMID:
20599962
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells.

Zhang M, Hu H, Zhang X, Lu W, Lim J, Eysteinsson T, Jacobson KA, Laties AM, Mitchell CH.

Neurochem Int. 2010 Jan;56(1):35-41. doi: 10.1016/j.neuint.2009.08.011. Epub 2009 Aug 31.

PMID:
19723551
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.

Mitchell CH, Lu W, Hu H, Zhang X, Reigada D, Zhang M.

Purinergic Signal. 2009 Jun;5(2):241-9. doi: 10.1007/s11302-009-9142-6. Epub 2009 Feb 25.

PMID:
19241145
[PubMed]
Free PMC Article
18.

The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.

Mitchell CH, Lu W, Hu H, Zhang X, Reigada D, Zhang M.

Purinergic Signal. 2008 Dec;4(4):313-21. doi: 10.1007/s11302-008-9125-z. Epub 2008 Oct 16.

PMID:
18923921
[PubMed]
Free PMC Article
19.

Purinergic signalling in the subretinal space: a role in the communication between the retina and the RPE.

Mitchell CH, Reigada D.

Purinergic Signal. 2008 Jun;4(2):101-7. doi: 10.1007/s11302-007-9054-2. Epub 2007 Mar 14.

PMID:
18368526
[PubMed]
Free PMC Article
20.

Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.

Liu J, Lu W, Reigada D, Nguyen J, Laties AM, Mitchell CH.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):772-80. doi: 10.1167/iovs.07-0675.

PMID:
18235027
[PubMed - indexed for MEDLINE]
Free PMC Article

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