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Page 1
The sacral chordoma margin.
Radaelli S, Fossati P, Stacchiotti S, Akiyama T, Asencio JM, Bandiera S, Boglione A, Boland P, Bolle S, Bruland Ø, Brunello A, Bruzzi P, Campanacci D, Cananzi F, Capanna R, Casadei R, Cordoba A, Court C, Dei Tos AP, DeLaney TF, De Paoli A, De Pas TM, Desai A, Di Brina L, Donati DM, Fabbri N, Fiore MR, Frezza A, Gambarotti M, Gasbarrini A, Georg P, Grignani G, Hindi N, Hug EB, Jones R, Kawai A, Krol AD, Le Grange F, Luzzati A, Marquina G, Martin-Benlloch JA, Mazzocco K, Navarria F, Navarria P, Parchi PD, Patel S, Pennacchioli E, Petrongari MG, Picci P, Pollock R, Porcu L, Quagliuolo V, Sangalli C, Scheipl S, Scotto GM, Spalek M, Steinmeier T, Timmermann B, Trama A, Uhl M, Valverde C, Varga PP, Verges R, Weber DC, Zoccali C, Casali PG, Sommer J, Gronchi A. Radaelli S, et al. Eur J Surg Oncol. 2020 Aug;46(8):1415-1422. doi: 10.1016/j.ejso.2020.04.028. Epub 2020 Apr 27. Eur J Surg Oncol. 2020. PMID: 32402509 Free article. Review.
OBJECTIVE: Aim of the manuscript is to discuss how to improve margins in sacral chordoma. BACKGROUND: Chordoma is a rare neoplasm, arising in half cases from the sacrum, with reported local failure in >50% after surgery. METHODS: A multidisciplinary meeting of th …
OBJECTIVE: Aim of the manuscript is to discuss how to improve margins in sacral chordoma. BACKGROUND: Chordoma is a rare neopl …
Surgical treatment of sacral chordoma: prognostic variables for local recurrence and overall survival.
Varga PP, Szövérfi Z, Fisher CG, Boriani S, Gokaslan ZL, Dekutoski MB, Chou D, Quraishi NA, Reynolds JJ, Luzzati A, Williams R, Fehlings MG, Germscheid NM, Lazary A, Rhines LD. Varga PP, et al. Eur Spine J. 2015 May;24(5):1092-101. doi: 10.1007/s00586-014-3728-6. Epub 2014 Dec 23. Eur Spine J. 2015. PMID: 25533857
PURPOSE: Sacral chordomas (SC) are rare, locally invasive, malignant neoplasms. Despite surgical resection and adjuvant therapies, local recurrence (LR) is common and overall survival (OS) is poor. ...
PURPOSE: Sacral chordomas (SC) are rare, locally invasive, malignant neoplasms. Despite surgical resection and adjuvant therapies, lo …
Current treatment strategy for newly diagnosed chordoma of the mobile spine and sacrum: results of an international survey.
Dea N, Fisher CG, Reynolds JJ, Schwab JH, Rhines LD, Gokaslan ZL, Bettegowda C, Sahgal A, Lazáry Á, Luzzati A, Boriani S, Gasbarrini A, Laufer I, Charest-Morin R, Wei F, Teixeira W, Germscheid NM, Hornicek FJ, DeLaney TF, Shin JH; AOSpine Knowledge Forum Tumor. Dea N, et al. J Neurosurg Spine. 2018 Oct 19;30(1):119-125. doi: 10.3171/2018.6.SPINE18362. J Neurosurg Spine. 2018. PMID: 30497218
OBJECTIVEThe purpose of this study was to investigate the spectrum of current treatment protocols for managing newly diagnosed chordoma of the mobile spine and sacrum.METHODSA survey on the treatment of spinal chordoma was distributed electronically to members of th …
OBJECTIVEThe purpose of this study was to investigate the spectrum of current treatment protocols for managing newly diagnosed chordoma
Bone sarcoma of the spine.
Schaser KD, Melcher I, Luzzati A, Disch AC. Schaser KD, et al. Recent Results Cancer Res. 2009;179:141-67. doi: 10.1007/978-3-540-77960-5_10. Recent Results Cancer Res. 2009. PMID: 19230539 Review.
., bone sarcomas of the spine, are inherently rare entities. Vertebral osteosarcomas and chordomas represent the largest groups, followed by the incidence of chondro-, fibro-, and Ewing's sarcomas. ...
., bone sarcomas of the spine, are inherently rare entities. Vertebral osteosarcomas and chordomas represent the largest groups, foll …
Spinal column chordoma: prognostic significance of clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival.
Bettegowda C, Yip S, Lo SL, Fisher CG, Boriani S, Rhines LD, Wang JY, Lazary A, Gambarotti M, Wang WL, Luzzati A, Dekutoski MB, Bilsky MH, Chou D, Fehlings MG, McCarthy EF, Quraishi NA, Reynolds JJ, Sciubba DM, Williams RP, Wolinsky JP, Zadnik PL, Zhang M, Germscheid NM, Kalampoki V, Varga PP, Gokaslan ZL; AOSpine Knowledge Forum Tumor. Bettegowda C, et al. Neuro Oncol. 2017 Mar 1;19(3):405-413. doi: 10.1093/neuonc/now156. Neuro Oncol. 2017. PMID: 27663388 Free PMC article.
BACKGROUND: Chordomas are rare, locally aggressive bony tumors associated with poor outcomes. Recently, the single nucleotide polymorphism (SNP) rs2305089 in the T (brachyury) gene was strongly associated with sporadic chordoma development, but its clinical utility …
BACKGROUND: Chordomas are rare, locally aggressive bony tumors associated with poor outcomes. Recently, the single nucleotide polymor …
Mobile spine chordoma: results of 166 patients from the AOSpine Knowledge Forum Tumor database.
Gokaslan ZL, Zadnik PL, Sciubba DM, Germscheid N, Goodwin CR, Wolinsky JP, Bettegowda C, Groves ML, Luzzati A, Rhines LD, Fisher CG, Varga PP, Dekutoski MB, Clarke MJ, Fehlings MG, Quraishi NA, Chou D, Reynolds JJ, Williams RP, Kawahara N, Boriani S. Gokaslan ZL, et al. J Neurosurg Spine. 2016 Apr;24(4):644-51. doi: 10.3171/2015.7.SPINE15201. Epub 2015 Dec 18. J Neurosurg Spine. 2016. PMID: 26682601 Free PMC article.
OBJECT: A chordoma is an indolent primary spinal tumor that has devastating effects on the patient's life. ...While multiple small and largely retrospective studies have investigated the outcomes following en bloc resection of chordomas in the sacrum, there have bee …
OBJECT: A chordoma is an indolent primary spinal tumor that has devastating effects on the patient's life. ...While multiple small an …
A novel scientific model for rare and often neglected neoplastic conditions.
Fisher CG, Goldschlager T, Boriani S, Varga PP, Fehlings MG, Bilsky MH, Dekutoski MB, Luzzati A, Williams RP, Berven S, Chou D, Reynolds JJ, Quraishi NA, Rhines LD, Bettegowda C, Gokaslan ZL. Fisher CG, et al. Evid Based Spine Care J. 2013 Oct;4(2):160-2. doi: 10.1055/s-0033-1357365. Evid Based Spine Care J. 2013. PMID: 24436717 Free PMC article.
A total of 1,495 tumor cases were captured and diagnosed as one of the 18 primary spine tumor subtypes listed (Fig. 1). The most prevalent diagnosis was chordoma (n = 344, 23%). There were 674 females and 821 males with a mean age of 43 19 years at the time of surgery. ...
A total of 1,495 tumor cases were captured and diagnosed as one of the 18 primary spine tumor subtypes listed (Fig. 1). The most prevalent d …
Four- and five- level en bloc spondylectomy for malignant spinal tumors.
Luzzati AD, Shah SP, Gagliano FS, Perrucchini GG, Fontanella W, Alloisio M. Luzzati AD, et al. Spine (Phila Pa 1976). 2014 Jan 15;39(2):E129-39. doi: 10.1097/BRS.0000000000000072. Spine (Phila Pa 1976). 2014. PMID: 24150433
Average age was 41.66 years (11-66). There were 8 primary malignant tumors: 3 chordomas, 3 osteosarcomas, 1 chondrosarcoma, 1 primary lung tumor and 1 metastatic alveolar soft part sarcoma. ...
Average age was 41.66 years (11-66). There were 8 primary malignant tumors: 3 chordomas, 3 osteosarcomas, 1 chondrosarcoma, 1 primary …
Wide Surgery in the Cervical Spine: Indications, Results, and Complications in a Series of 30 Patients Affected by Primary Bone Tumors.
Luzzati A, Scotto GM, Cannavò L, Orlando G, Scotto di Uccio A, Baldi J, Zoccali C. Luzzati A, et al. World Neurosurg. 2021 Nov;155:e240-e248. doi: 10.1016/j.wneu.2021.08.054. Epub 2021 Aug 20. World Neurosurg. 2021. PMID: 34419658
RESULTS: Only 17 of 30 patients had not been previously treated at presentation. Osteosarcoma and chordoma were the most frequent tumors, and pain was reported in all cases. ...
RESULTS: Only 17 of 30 patients had not been previously treated at presentation. Osteosarcoma and chordoma were the most frequent tum …
11 results