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TheraSphere Yttrium-90 Glass Microspheres Combined With Chemotherapy Versus Chemotherapy Alone in Second-Line Treatment of Patients With Metastatic Colorectal Carcinoma of the Liver: Protocol for the EPOCH Phase 3 Randomized Clinical Trial.
Chauhan N, Mulcahy MF, Salem R, Benson Iii AB, Boucher E, Bukovcan J, Cosgrove D, Laframboise C, Lewandowski RJ, Master F, El-Rayes B, Strosberg JR, Sze DY, Sharma RA. Chauhan N, et al. JMIR Res Protoc. 2019 Jan 17;8(1):e11545. doi: 10.2196/11545. JMIR Res Protoc. 2019. PMID: 30664496 Free PMC article.
OBJECTIVE: The objective of this study is to evaluate the efficacy and safety of transarterial radioembolization (TARE) with TheraSphere yttrium-90 ((90)Y) glass microspheres combined with second-line therapy in patients with mCRC of the liver who had disease …
OBJECTIVE: The objective of this study is to evaluate the efficacy and safety of transarterial radioembolization (TARE) with TheraSphere …
Systematic review and network meta-analyses of third-line treatments for metastatic colorectal cancer.
Walter T, Hawkins NS, Pollock RF, Colaone F, Shergill S, Ross PJ. Walter T, et al. J Cancer Res Clin Oncol. 2020 Oct;146(10):2575-2587. doi: 10.1007/s00432-020-03315-6. Epub 2020 Jul 27. J Cancer Res Clin Oncol. 2020. PMID: 32715436 Free PMC article.
BACKGROUND: Limited treatment options are available in chemotherapy-refractory metastatic colorectal cancer (mCRC). The objective was to conduct a systematic literature review (SLR) and exploratory network meta-analysis (NMA) to compare the tolerability and effectiveness o …
BACKGROUND: Limited treatment options are available in chemotherapy-refractory metastatic colorectal cancer (mCRC). The objective was …
Transarterial Selective Internal Radiation Therapy with Yttrium-90 for Liver Metastatic Urothelial Carcinoma of the Ureter as a Bridging Therapy to Immunotherapy: A Case Report with a 10-Year Follow-Up.
Schmid BP, Silva Cunha MJ, Moreira Valle LG, Galastri FL, Affonso BB, Falsarella PM, Kaliks Guendelmann RA, Garcia RG, Nasser F. Schmid BP, et al. Case Rep Oncol. 2023 Aug 24;16(1):711-717. doi: 10.1159/000531787. eCollection 2023 Jan-Dec. Case Rep Oncol. 2023. PMID: 37933309 Free PMC article.
Herein, we describe a case of a 54-year-old patient diagnosed with transitional cell carcinoma of the left ureter submitted to left nephroureterectomy (pT3N2M0) and methotrexate, vinblastine, doxorubicin, and cisplatin adjuvant chemotherapy. A single liver metastasis …
Herein, we describe a case of a 54-year-old patient diagnosed with transitional cell carcinoma of the left ureter submitted to left nephrour …
Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis.
Vente MA, Wondergem M, van der Tweel I, van den Bosch MA, Zonnenberg BA, Lam MG, van Het Schip AD, Nijsen JF. Vente MA, et al. Eur Radiol. 2009 Apr;19(4):951-9. doi: 10.1007/s00330-008-1211-7. Epub 2008 Nov 7. Eur Radiol. 2009. PMID: 18989675
Based on an extensive literature search, six groups were formed. Determinants were cancer type, microsphere type, chemotherapy protocol used, and stage (deployment in first-line or as salvage therapy). ...In mCRC, (90)Y-RE delivers high response rates, especi …
Based on an extensive literature search, six groups were formed. Determinants were cancer type, microsphere type, chemotherapy …
SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer.
van Hazel GA, Heinemann V, Sharma NK, Findlay MP, Ricke J, Peeters M, Perez D, Robinson BA, Strickland AH, Ferguson T, Rodríguez J, Kröning H, Wolf I, Ganju V, Walpole E, Boucher E, Tichler T, Shacham-Shmueli E, Powell A, Eliadis P, Isaacs R, Price D, Moeslein F, Taieb J, Bower G, Gebski V, Van Buskirk M, Cade DN, Thurston K, Gibbs P. van Hazel GA, et al. J Clin Oncol. 2016 May 20;34(15):1723-31. doi: 10.1200/JCO.2015.66.1181. Epub 2016 Feb 22. J Clin Oncol. 2016. PMID: 26903575 Clinical Trial.
PURPOSE: SIRFLOX was a randomized, multicenter trial designed to assess the efficacy and safety of adding selective internal radiation therapy (SIRT) using yttrium-90 resin microspheres to standard fluorouracil, leucovorin, and oxaliplatin (FOLFOX)-based c …
PURPOSE: SIRFLOX was a randomized, multicenter trial designed to assess the efficacy and safety of adding selective internal radiation th …
90Y microsphere treatment of unresectable liver metastases: changes in 18F-FDG uptake and tumour size on PET/CT.
Bienert M, McCook B, Carr BI, Geller DA, Sheetz M, Tutor C, Amesur N, Avril N. Bienert M, et al. Eur J Nucl Med Mol Imaging. 2005 Jul;32(7):778-87. doi: 10.1007/s00259-004-1752-1. Epub 2005 Mar 17. Eur J Nucl Med Mol Imaging. 2005. PMID: 15772860
METHODS: Five patients with unresectable liver metastases who had failed multiple prior chemotherapy regimens received seven 90Y microsphere treatments to a single liver lobe. ...CONCLUSION: The metabolic information obtained from FDG-PET/CT seems to provide …
METHODS: Five patients with unresectable liver metastases who had failed multiple prior chemotherapy regimens received seven 9 …