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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 1
2001 1
2002 2
2003 1
2004 1
2006 1
2007 1
2008 3
2011 1
2012 1
2013 1
2014 1
2017 1
2018 2
2020 2
2021 1
2022 7
2023 1
2024 2

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29 results

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Page 1
ApoE and Neurodegenerative Diseases in Aging.
Yin Y, Wang Z. Yin Y, et al. Adv Exp Med Biol. 2018;1086:77-92. doi: 10.1007/978-981-13-1117-8_5. Adv Exp Med Biol. 2018. PMID: 30232753 Review.
Among the three polymorphic alleles, apoE epsilon4 is the most risk gene. ApoE is the main ligand for the low-density lipoprotein (LDL) receptor and the LDL receptor-related protein (LRP), functioning as the component of plasma lipoproteins in the transportat …
Among the three polymorphic alleles, apoE epsilon4 is the most risk gene. ApoE is the main ligand for the low-density lipoprotein (LDL …
There is urgent need to treat atherosclerotic cardiovascular disease risk earlier, more intensively, and with greater precision: A review of current practice and recommendations for improved effectiveness.
Makover ME, Shapiro MD, Toth PP. Makover ME, et al. Am J Prev Cardiol. 2022 Aug 6;12:100371. doi: 10.1016/j.ajpc.2022.100371. eCollection 2022 Dec. Am J Prev Cardiol. 2022. PMID: 36124049 Free PMC article. Review.
Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke, unstable angina, and death. ASCVD also impacts risk for dementia, chronic kidney d …
Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is etiologic for such acute cardiovascular events as myo …
Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study.
Cupido AJ, Reeskamp LF, Hingorani AD, Finan C, Asselbergs FW, Hovingh GK, Schmidt AF. Cupido AJ, et al. JAMA Cardiol. 2022 Sep 1;7(9):955-964. doi: 10.1001/jamacardio.2022.2333. JAMA Cardiol. 2022. PMID: 35921096 Free PMC article.
IMPORTANCE: Cholesteryl ester transfer protein inhibition (CETP) has been shown to increase levels of high-density lipoprotein cholesterol (HDL-C) and reduce levels of low-density lipoprotein cholesterol (LDL-C). ...MAIN OUTCOMES AND MEASURES: Blood lipid and …
IMPORTANCE: Cholesteryl ester transfer protein inhibition (CETP) has been shown to increase levels of high-density lipoprotein cholestero …
Cholesterol-independent effects of statins and new therapeutic targets: ischemic stroke and dementia.
Miida T, Hirayama S, Nakamura Y. Miida T, et al. J Atheroscler Thromb. 2004;11(5):253-64. doi: 10.5551/jat.11.253. J Atheroscler Thromb. 2004. PMID: 15557707 Free article. Review.
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or "statins", are used as cholesterol-lowering agents worldwide. Statins inhibit cholesterol biosynthesis, leading to enhanced uptake of low-density lipoprotein (LDL) from the circulati …
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or "statins", are used as cholesterol-lowering agents world …
Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke.
De Marchis GM, Dittrich TD, Malik R, Zietz AV, Kriemler LF, Ference BA, Dichgans M, Georgakis MK. De Marchis GM, et al. Atherosclerosis. 2022 Nov;361:41-46. doi: 10.1016/j.atherosclerosis.2022.09.007. Epub 2022 Sep 26. Atherosclerosis. 2022. PMID: 36244797 Free article.
We aimed to assess whether genetically proxied PCSK9 inhibition influences lipoprotein(a) (Lp(a)), and whether any such effect could mediate its effects on coronary artery disease (CAD) and ischemic stroke (IS). METHODS: To explore associations between the genetic p …
We aimed to assess whether genetically proxied PCSK9 inhibition influences lipoprotein(a) (Lp(a)), and whether any such effect could mediate …
Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.
Georgakis MK, Malik R, Richardson TG, Howson JMM, Anderson CD, Burgess S, Hovingh GK, Dichgans M, Gill D. Georgakis MK, et al. BMC Med. 2022 Aug 11;20(1):245. doi: 10.1186/s12916-022-02446-6. BMC Med. 2022. PMID: 35948913 Free PMC article.
We then applied linear and non-linear Mendelian randomization analyses exploring associations with a combined endpoint of incident coronary artery disease, ischemic stroke, peripheral artery disease, aortic aneurysm, and cardiovascular death stratifying by baseline …
We then applied linear and non-linear Mendelian randomization analyses exploring associations with a combined endpoint of incident coronary …
Prevention of stroke and dementia with statins: Effects beyond lipid lowering.
Vaughan CJ. Vaughan CJ. Am J Cardiol. 2003 Feb 20;91(4A):23B-29B. doi: 10.1016/s0002-9149(02)03270-8. Am J Cardiol. 2003. PMID: 12615295 Review.
Stroke is a major cause of mortality and morbidity. The epidemiologic association between elevated serum cholesterol and stroke risk is controversial. ...Further studies are needed to fully address the role of statins in the prevention of stroke in pat …
Stroke is a major cause of mortality and morbidity. The epidemiologic association between elevated serum cholesterol and st …
Mediterranean diet in healthy lifestyle and prevention of stroke.
Demarin V, Lisak M, Morović S. Demarin V, et al. Acta Clin Croat. 2011 Mar;50(1):67-77. Acta Clin Croat. 2011. PMID: 22034786 Review.
Several studies support favorable effects of Mediterranean diet on plasma lipid profile: reduction of total and plasma LDL cholesterol levels, plasma triglyceride levels, and apo-B and VLDL concentrations, and an increase in plasma HDL cholesterol levels. ... …
Several studies support favorable effects of Mediterranean diet on plasma lipid profile: reduction of total and plasma LDL cholest …
Altered lipid metabolism in brain injury and disorders.
Adibhatla RM, Hatcher JF. Adibhatla RM, et al. Subcell Biochem. 2008;49:241-68. doi: 10.1007/978-1-4020-8831-5_9. Subcell Biochem. 2008. PMID: 18751914 Free PMC article. Review.
Deregulated lipid metabolism may be of particular importance for CNS injuries and disorders, as this organ has the highest lipid concentration next to adipose tissue. Atherosclerosis (a risk factor for ischemic stroke) results from accumulation of LDL-derived …
Deregulated lipid metabolism may be of particular importance for CNS injuries and disorders, as this organ has the highest lipid concentrati …
Use of lipid-lowering therapy after ischaemic stroke and expected benefit from intensification of treatment.
Gynnild MN, Hageman SHJ, Spigset O, Lydersen S, Saltvedt I, Dorresteijn JAN, Visseren FLJ, Ellekjær H. Gynnild MN, et al. Open Heart. 2022 Apr;9(1):e001972. doi: 10.1136/openhrt-2022-001972. Open Heart. 2022. PMID: 35459718 Free PMC article.
OBJECTIVES: Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) events. ...METHODS: The Norwegian COgnitive Impairment After STroke (Nor-COAST) study, a multicentre prospective cohort study, collec …
OBJECTIVES: Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) …
29 results