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Results: 1 to 20 of 91

1.

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA.

Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114.

2.

Monitoring pancreatic carcinogenesis by the molecular imaging of cathepsin E in vivo using confocal laser endomicroscopy.

Li H, Li Y, Cui L, Wang B, Cui W, Li M, Cheng Y.

PLoS One. 2014 Sep 3;9(9):e106566. doi: 10.1371/journal.pone.0106566. eCollection 2014.

3.

The influence of linker length on the properties of cathepsin S cleavable (177)Lu-labeled HPMA copolymers for pancreatic cancer imaging.

Shi W, Ogbomo SM, Wagh NK, Zhou Z, Jia Y, Brusnahan SK, Garrison JC.

Biomaterials. 2014 Jul;35(22):5760-70. doi: 10.1016/j.biomaterials.2014.03.056. Epub 2014 Apr 19.

PMID:
24755528
4.

Cathepsin B: multiple roles in cancer.

Aggarwal N, Sloane BF.

Proteomics Clin Appl. 2014 Jun;8(5-6):427-37. doi: 10.1002/prca.201300105. Epub 2014 Mar 26. Review.

PMID:
24677670
5.

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.

Ruffell B, Affara NI, Cottone L, Junankar S, Johansson M, DeNardo DG, Korets L, Reinheckel T, Sloane BF, Bogyo M, Coussens LM.

Genes Dev. 2013 Oct 1;27(19):2086-98. doi: 10.1101/gad.224899.113. Epub 2013 Sep 24.

6.

Cathepsin B contributes to autophagy-related 7 (Atg7)-induced nod-like receptor 3 (NLRP3)-dependent proinflammatory response and aggravates lipotoxicity in rat insulinoma cell line.

Li S, Du L, Zhang L, Hu Y, Xia W, Wu J, Zhu J, Chen L, Zhu F, Li C, Yang S.

J Biol Chem. 2013 Oct 18;288(42):30094-104. doi: 10.1074/jbc.M113.494286. Epub 2013 Aug 28.

7.

Prognostic significance of extracellular matrix degrading enzymes-cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer.

Singh N, Das P, Datta Gupta S, Sahni P, Pandey RM, Gupta S, Chauhan SS, Saraya A.

Cancer Invest. 2013 Aug;31(7):461-71. doi: 10.3109/07357907.2013.820318.

PMID:
23915070
8.

Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.

Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R.

Neoplasia. 2013 Jul;15(7):684-93.

9.

177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model.

Ogbomo SM, Shi W, Wagh NK, Zhou Z, Brusnahan SK, Garrison JC.

Nucl Med Biol. 2013 Jul;40(5):606-17. doi: 10.1016/j.nucmedbio.2013.01.011. Epub 2013 Apr 24.

10.

Pancreatic cancer-associated Cathepsin E as a drug activator.

Abd-Elgaliel WR, Cruz-Monserrate Z, Wang H, Logsdon CD, Tung CH.

J Control Release. 2013 May 10;167(3):221-7. doi: 10.1016/j.jconrel.2013.02.007. Epub 2013 Feb 26.

11.

Cathepsins and pancreatic cancer: the 2012 update.

Sulpizio S, Franceschini N, Piattelli A, Di Sebastiano P, Innocenti P, Selvaggi F.

Pancreatology. 2012 Sep-Oct;12(5):395-401. doi: 10.1016/j.pan.2012.07.011. Epub 2012 Jul 20. Review.

PMID:
23127526
12.

Serum CA19-9, cathepsin D, and matrix metalloproteinase-7 as a diagnostic panel for pancreatic ductal adenocarcinoma.

Park HD, Kang ES, Kim JW, Lee KT, Lee KH, Park YS, Park JO, Lee J, Heo JS, Choi SH, Choi DW, Kim S, Lee JK, Lee SY.

Proteomics. 2012 Dec;12(23-24):3590-7. doi: 10.1002/pmic.201200101.

PMID:
23065739
13.

Global identification of peptidase specificity by multiplex substrate profiling.

O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS.

Nat Methods. 2012 Nov;9(11):1095-100. doi: 10.1038/nmeth.2182. Epub 2012 Sep 30.

14.

Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells.

Wei J, Liu H, Liu M, Wu N, Zhao J, Xiao L, Han L, Chu E, Lin X.

Oncol Rep. 2012 Oct;28(4):1339-45. doi: 10.3892/or.2012.1921. Epub 2012 Jul 19.

PMID:
22825128
15.

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.

Martino L, Masini M, Novelli M, Beffy P, Bugliani M, Marselli L, Masiello P, Marchetti P, De Tata V.

PLoS One. 2012;7(5):e36188. doi: 10.1371/journal.pone.0036188. Epub 2012 May 1.

16.
17.

Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis.

Shchors K, Nozawa H, Xu J, Rostker F, Swigart-Brown L, Evan G, Hanahan D.

Oncogene. 2013 Jan 24;32(4):502-13. doi: 10.1038/onc.2012.60. Epub 2012 Mar 5.

PMID:
22391572
18.

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

Lines KE, Chelala C, Dmitrovic B, Wijesuriya N, Kocher HM, Marshall JF, Crnogorac-Jurcevic T.

Am J Pathol. 2012 Apr;180(4):1485-94. doi: 10.1016/j.ajpath.2011.12.031. Epub 2012 Feb 11.

19.

Targeting cathepsins: a new glimmer of hope for pancreatic cancer therapy?

Michl P.

Gut. 2012 Jun;61(6):790-1. doi: 10.1136/gutjnl-2011-301816. Epub 2012 Jan 27. No abstract available.

PMID:
22287597
20.

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity.

Kwok HF, Buick RJ, Kuehn D, Gormley JA, Doherty D, Jaquin TJ, McClurg A, Ward C, Byrne T, Jaworski J, Leung KL, Snoddy P, McAnally C, Burden RE, Gray B, Lowry J, Sermadiras I, Gruszka N, Courtenay-Luck N, Kissenpfennig A, Scott CJ, Johnston JA, Olwill SA.

Mol Cancer. 2011 Dec 14;10:147. doi: 10.1186/1476-4598-10-147.

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