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Results: 1 to 20 of 87

1.

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.

Ruffell B, Affara NI, Cottone L, Junankar S, Johansson M, DeNardo DG, Korets L, Reinheckel T, Sloane BF, Bogyo M, Coussens LM.

Genes Dev. 2013 Oct 1;27(19):2086-98. doi: 10.1101/gad.224899.113. Epub 2013 Sep 24.

PMID:
24065739
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cathepsin B contributes to autophagy-related 7 (Atg7)-induced nod-like receptor 3 (NLRP3)-dependent proinflammatory response and aggravates lipotoxicity in rat insulinoma cell line.

Li S, Du L, Zhang L, Hu Y, Xia W, Wu J, Zhu J, Chen L, Zhu F, Li C, Yang S.

J Biol Chem. 2013 Oct 18;288(42):30094-104. doi: 10.1074/jbc.M113.494286. Epub 2013 Aug 28.

PMID:
23986436
[PubMed - indexed for MEDLINE]
3.

Prognostic significance of extracellular matrix degrading enzymes-cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer.

Singh N, Das P, Datta Gupta S, Sahni P, Pandey RM, Gupta S, Chauhan SS, Saraya A.

Cancer Invest. 2013 Aug;31(7):461-71. doi: 10.3109/07357907.2013.820318.

PMID:
23915070
[PubMed - indexed for MEDLINE]
4.

Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.

Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R.

Neoplasia. 2013 Jul;15(7):684-93.

PMID:
23814481
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model.

Ogbomo SM, Shi W, Wagh NK, Zhou Z, Brusnahan SK, Garrison JC.

Nucl Med Biol. 2013 Jul;40(5):606-17. doi: 10.1016/j.nucmedbio.2013.01.011. Epub 2013 Apr 24.

PMID:
23622691
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pancreatic cancer-associated Cathepsin E as a drug activator.

Abd-Elgaliel WR, Cruz-Monserrate Z, Wang H, Logsdon CD, Tung CH.

J Control Release. 2013 May 10;167(3):221-7. doi: 10.1016/j.jconrel.2013.02.007. Epub 2013 Feb 26.

PMID:
23422726
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cathepsins and pancreatic cancer: the 2012 update.

Sulpizio S, Franceschini N, Piattelli A, Di Sebastiano P, Innocenti P, Selvaggi F.

Pancreatology. 2012 Sep-Oct;12(5):395-401. doi: 10.1016/j.pan.2012.07.011. Epub 2012 Jul 20. Review.

PMID:
23127526
[PubMed - indexed for MEDLINE]
8.

Serum CA19-9, cathepsin D, and matrix metalloproteinase-7 as a diagnostic panel for pancreatic ductal adenocarcinoma.

Park HD, Kang ES, Kim JW, Lee KT, Lee KH, Park YS, Park JO, Lee J, Heo JS, Choi SH, Choi DW, Kim S, Lee JK, Lee SY.

Proteomics. 2012 Dec;12(23-24):3590-7. doi: 10.1002/pmic.201200101.

PMID:
23065739
[PubMed - indexed for MEDLINE]
9.

Global identification of peptidase specificity by multiplex substrate profiling.

O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS.

Nat Methods. 2012 Nov;9(11):1095-100. doi: 10.1038/nmeth.2182. Epub 2012 Sep 30.

PMID:
23023596
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells.

Wei J, Liu H, Liu M, Wu N, Zhao J, Xiao L, Han L, Chu E, Lin X.

Oncol Rep. 2012 Oct;28(4):1339-45. doi: 10.3892/or.2012.1921. Epub 2012 Jul 19.

PMID:
22825128
[PubMed - indexed for MEDLINE]
11.

Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets.

Martino L, Masini M, Novelli M, Beffy P, Bugliani M, Marselli L, Masiello P, Marchetti P, De Tata V.

PLoS One. 2012;7(5):e36188. doi: 10.1371/journal.pone.0036188. Epub 2012 May 1.

PMID:
22563482
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme.

Tsume Y, Amidon GL.

Molecules. 2012 Mar 26;17(4):3672-89. doi: 10.3390/molecules17043672.

PMID:
22450679
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis.

Shchors K, Nozawa H, Xu J, Rostker F, Swigart-Brown L, Evan G, Hanahan D.

Oncogene. 2013 Jan 24;32(4):502-13. doi: 10.1038/onc.2012.60. Epub 2012 Mar 5.

PMID:
22391572
[PubMed - indexed for MEDLINE]
14.

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

Lines KE, Chelala C, Dmitrovic B, Wijesuriya N, Kocher HM, Marshall JF, Crnogorac-Jurcevic T.

Am J Pathol. 2012 Apr;180(4):1485-94. doi: 10.1016/j.ajpath.2011.12.031. Epub 2012 Feb 11.

PMID:
22330678
[PubMed - indexed for MEDLINE]
15.

Targeting cathepsins: a new glimmer of hope for pancreatic cancer therapy?

Michl P.

Gut. 2012 Jun;61(6):790-1. doi: 10.1136/gutjnl-2011-301816. Epub 2012 Jan 27. No abstract available.

PMID:
22287597
[PubMed - indexed for MEDLINE]
16.

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity.

Kwok HF, Buick RJ, Kuehn D, Gormley JA, Doherty D, Jaquin TJ, McClurg A, Ward C, Byrne T, Jaworski J, Leung KL, Snoddy P, McAnally C, Burden RE, Gray B, Lowry J, Sermadiras I, Gruszka N, Courtenay-Luck N, Kissenpfennig A, Scott CJ, Johnston JA, Olwill SA.

Mol Cancer. 2011 Dec 14;10:147. doi: 10.1186/1476-4598-10-147.

PMID:
22168338
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice.

Gopinathan A, Denicola GM, Frese KK, Cook N, Karreth FA, Mayerle J, Lerch MM, Reinheckel T, Tuveson DA.

Gut. 2012 Jun;61(6):877-84. doi: 10.1136/gutjnl-2011-300850. Epub 2011 Dec 9.

PMID:
22157328
[PubMed - indexed for MEDLINE]
18.

Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.

Cruz-Monserrate Z, Abd-Elgaliel WR, Grote T, Deng D, Ji B, Arumugam T, Wang H, Tung CH, Logsdon CD.

Gut. 2012 Sep;61(9):1315-22. doi: 10.1136/gutjnl-2011-300544. Epub 2011 Nov 7.

PMID:
22068166
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D.

Dumartin L, Whiteman HJ, Weeks ME, Hariharan D, Dmitrovic B, Iacobuzio-Donahue CA, Brentnall TA, Bronner MP, Feakins RM, Timms JF, Brennan C, Lemoine NR, Crnogorac-Jurcevic T.

Cancer Res. 2011 Nov 15;71(22):7091-102. doi: 10.1158/0008-5472.CAN-11-1367. Epub 2011 Sep 26.

PMID:
21948970
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells.

Udelnow A, Kreyes A, Ellinger S, Landfester K, Walther P, Klapperstueck T, Wohlrab J, Henne-Bruns D, Knippschild U, Würl P.

PLoS One. 2011;6(5):e20143. doi: 10.1371/journal.pone.0020143. Epub 2011 May 24.

PMID:
21629657
[PubMed - indexed for MEDLINE]
Free PMC Article

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