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Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.

Blackburn EH, Epel ES, Lin J.

Science. 2015 Dec 4;350(6265):1193-8. doi: 10.1126/science.aab3389. Review.


Hepatic Angiosarcoma with Dyskeratosis Congenita.

Horiguchi N, Kakizaki S, Iizuka K, Hagiwara S, Ohyama T, Yamazaki Y, Shibusawa N, Sato K, Kusano M, Nakazato Y, Yamada M.

Intern Med. 2015;54(22):2867-72. doi: 10.2169/internalmedicine.54.5206. Epub 2015 Nov 15.


Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer.

Hubbard GK, Mutton LN, Khalili M, McMullin RP, Hicks JL, Bianchi-Frias D, Horn LA, Kulac I, Moubarek MS, Nelson PS, Yegnasubramanian S, De Marzo AM, Bieberich CJ.

Cancer Res. 2016 Jan 15;76(2):283-92. doi: 10.1158/0008-5472.CAN-14-3280. Epub 2015 Nov 10.


Impact of telomere length on survival in classic and variant hairy cell leukemia.

Arons E, Zhou H, Edelman DC, Gomez A, Steinberg SM, Petersen D, Wang Y, Meltzer PS, Kreitman RJ.

Leuk Res. 2015 Dec;39(12):1360-6. doi: 10.1016/j.leukres.2015.09.015. Epub 2015 Sep 24.


XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma.

Cheng J, Liu W, Zeng X, Zhang B, Guo Y, Qiu M, Jiang C, Wang H, Wu Z, Meng M, Zhuang H, Zhao L, Hao J, Cai Q, Xie D, Pang Q, Wang P, Yuan Z, Qian D.

Cancer Sci. 2015 Dec;106(12):1678-86. doi: 10.1111/cas.12820. Epub 2015 Nov 6.


PinX1 is up-regulated and associated with poor patients' survival in gliomas.

Bai J, Chen YS, Mei PJ, Liu QH, Du Y, Zheng JN.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):6952-9. eCollection 2015.


Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.

Strefford JC, Kadalayil L, Forster J, Rose-Zerilli MJ, Parker A, Lin TT, Heppel N, Norris K, Gardiner A, Davies Z, Gonzalez de Castro D, Else M, Steele AJ, Parker H, Stankovic T, Pepper C, Fegan C, Baird D, Collins A, Catovsky D, Oscier DG.

Leukemia. 2015 Dec;29(12):2411-4. doi: 10.1038/leu.2015.217. Epub 2015 Aug 10. No abstract available.


Alternative lengthening of telomeres phenotype in malignant vascular tumors is highly associated with loss of ATRX expression and is frequently observed in hepatic angiosarcomas.

Liau JY, Tsai JH, Yang CY, Lee JC, Liang CW, Hsu HH, Jeng YM.

Hum Pathol. 2015 Sep;46(9):1360-6. doi: 10.1016/j.humpath.2015.05.019. Epub 2015 Jun 5.


The Association between Telomere Length and Cancer Prognosis: Evidence from a Meta-Analysis.

Zhang C, Chen X, Li L, Zhou Y, Wang C, Hou S.

PLoS One. 2015 Jul 15;10(7):e0133174. doi: 10.1371/journal.pone.0133174. eCollection 2015.


TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma.

Mosrati MA, Malmström A, Lysiak M, Krysztofiak A, Hallbeck M, Milos P, Hallbeck AL, Bratthäll C, Strandéus M, Stenmark-Askmalm M, Söderkvist P.

Oncotarget. 2015 Jun 30;6(18):16663-73.


Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002.

Needham BL, Rehkopf D, Adler N, Gregorich S, Lin J, Blackburn EH, Epel ES.

Epidemiology. 2015 Jul;26(4):528-35. doi: 10.1097/EDE.0000000000000299.


Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas.

Lee JC, Jeng YM, Liau JY, Tsai JH, Hsu HH, Yang CY.

Mod Pathol. 2015 Aug;28(8):1064-73. doi: 10.1038/modpathol.2015.67. Epub 2015 May 29.


Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort.

Nsengimana J, Laye J, Filia A, Walker C, Jewell R, Van den Oord JJ, Wolter P, Patel P, Sucker A, Schadendorf D, Jönsson GB, Bishop DT, Newton-Bishop J.

Oncotarget. 2015 May 10;6(13):11683-93.


Peripheral blood leukocyte telomere length and mortality among 64,637 individuals from the general population.

Rode L, Nordestgaard BG, Bojesen SE.

J Natl Cancer Inst. 2015 Apr 10;107(6):djv074. doi: 10.1093/jnci/djv074. Print 2015 Jun.


Oral squamous cancer cell exploits hnRNP A1 to regulate cell cycle and proliferation.

Yu C, Guo J, Liu Y, Jia J, Jia R, Fan M.

J Cell Physiol. 2015 Sep;230(9):2252-61. doi: 10.1002/jcp.24956.


Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients.

Simpson K, Jones RE, Grimstead JW, Hills R, Pepper C, Baird DM.

Mol Oncol. 2015 Jun;9(6):1186-93. doi: 10.1016/j.molonc.2015.02.003. Epub 2015 Feb 25.


Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.

Spiegl-Kreinecker S, Lötsch D, Ghanim B, Pirker C, Mohr T, Laaber M, Weis S, Olschowski A, Webersinke G, Pichler J, Berger W.

Neuro Oncol. 2015 Sep;17(9):1231-40. doi: 10.1093/neuonc/nov010. Epub 2015 Feb 13.


Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.

Arora A, Abdel-Fatah TM, Agarwal D, Doherty R, Moseley PM, Aleskandarany MA, Green AR, Ball G, Alshareeda AT, Rakha EA, Chan SY, Ellis IO, Madhusudan S.

Mol Cancer Ther. 2015 Apr;14(4):1057-65. doi: 10.1158/1535-7163.MCT-14-0939. Epub 2015 Feb 11.


Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients.

Ozden S, Tiber PM, Ozgen Z, Ozyurt H, Serakinci N, Orun O.

Biol Res. 2014 Nov 25;47:61. doi: 10.1186/0717-6287-47-61.


Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo.

Hirashima K, Seimiya H.

Nucleic Acids Res. 2015 Feb 27;43(4):2022-32. doi: 10.1093/nar/gkv063. Epub 2015 Feb 4.

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