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    Results: 1 to 20 of 88

    1.

    Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.

    Edrey YH, Medina DX, Gaczynska M, Osmulski PA, Oddo S, Caccamo A, Buffenstein R.

    Neurobiol Aging. 2013 Apr 22. doi:pii: S0197-4580(13)00151-6. 10.1016/j.neurobiolaging.2013.03.032. [Epub ahead of print]

    PMID:
    23618870
    [PubMed - as supplied by publisher]
    2.

    Elevated protein carbonylation and oxidative stress do not affect protein structure and function in the long-living naked-mole rat: A proteomic approach.

    De Waal EM, Liang H, Pierce A, Hamilton RT, Buffenstein R, Chaudhuri AR.

    Biochem Biophys Res Commun. 2013 Apr 22. doi:pii: S0006-291X(13)00645-1. 10.1016/j.bbrc.2013.04.019. [Epub ahead of print]

    PMID:
    23618867
    [PubMed - as supplied by publisher]
    3.

    Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.

    Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H.

    Am J Physiol Regul Integr Comp Physiol. 2013 Mar 1;304(5):R343-55. doi: 10.1152/ajpregu.00139.2012. Epub 2013 Jan 16.

    PMID:
    23325454
    [PubMed - indexed for MEDLINE]
    4.

    The Naked Mole-Rat Response to Oxidative Stress: Just Deal with It.

    Lewis KN, Andziak B, Yang T, Buffenstein R.

    Antioxid Redox Signal. 2012 Dec 7. [Epub ahead of print]

    PMID:
    23025341
    [PubMed - as supplied by publisher]
    5.

    Stress resistance in the naked mole-rat: the bare essentials - a mini-review.

    Lewis KN, Mele J, Hornsby PJ, Buffenstein R.

    Gerontology. 2012;58(5):453-62. doi: 10.1159/000335966. Epub 2012 May 10.

    PMID:
    22572398
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.

    Rodriguez KA, Edrey YH, Osmulski P, Gaczynska M, Buffenstein R.

    PLoS One. 2012;7(5):e35890. doi: 10.1371/journal.pone.0035890. Epub 2012 May 2.

    PMID:
    22567116
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat.

    Grimes KM, Lindsey ML, Gelfond JA, Buffenstein R.

    J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):384-94. doi: 10.1093/gerona/glr222. Epub 2012 Feb 24.

    PMID:
    22367435
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus.

    Peterson BL, Larson J, Buffenstein R, Park TJ, Fall CP.

    PLoS One. 2012;7(2):e31568. doi: 10.1371/journal.pone.0031568. Epub 2012 Feb 21.

    PMID:
    22363676
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity.

    Edrey YH, Casper D, Huchon D, Mele J, Gelfond JA, Kristan DM, Nevo E, Buffenstein R.

    Aging Cell. 2012 Apr;11(2):213-22. doi: 10.1111/j.1474-9726.2011.00772.x. Epub 2011 Dec 29.

    PMID:
    22103690
    [PubMed - indexed for MEDLINE]
    10.

    RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

    Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, Church GM.

    PLoS One. 2011;6(11):e26729. doi: 10.1371/journal.pone.0026729. Epub 2011 Nov 3.

    PMID:
    22073188
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Genome sequencing reveals insights into physiology and longevity of the naked mole rat.

    Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA, Yang P, Yim SH, Zhao X, Kasaikina MV, Stoletzki N, Peng C, Polak P, Xiong Z, Kiezun A, Zhu Y, Chen Y, Kryukov GV, Zhang Q, Peshkin L, Yang L, Bronson RT, Buffenstein R, Wang B, Han C, Li Q, Chen L, Zhao W, Sunyaev SR, Park TJ, Zhang G, Wang J, Gladyshev VN.

    Nature. 2011 Oct 12;479(7372):223-7. doi: 10.1038/nature10533.

    PMID:
    21993625
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent.

    Rodriguez KA, Wywial E, Perez VI, Lambert AJ, Edrey YH, Lewis KN, Grimes K, Lindsey ML, Brand MD, Buffenstein R.

    Curr Pharm Des. 2011;17(22):2290-307. Review.

    PMID:
    21736541
    [PubMed - indexed for MEDLINE]
    13.

    Comparative studies of oxidative stress and mitochondrial function in aging.

    Shi Y, Buffenstein R, Pulliam DA, Van Remmen H.

    Integr Comp Biol. 2010 Nov;50(5):869-79. doi: 10.1093/icb/icq079. Epub 2010 Jul 2.

    PMID:
    21558246
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant?

    Bhattacharya A, Leonard S, Tardif S, Buffenstein R, Fischer KE, Richardson A, Austad SN, Chaudhuri AR.

    Aging Cell. 2011 Aug;10(4):720-3. doi: 10.1111/j.1474-9726.2011.00712.x. Epub 2011 May 6.

    PMID:
    21463461
    [PubMed - indexed for MEDLINE]
    15.

    Successful aging and sustained good health in the naked mole rat: a long-lived mammalian model for biogerontology and biomedical research.

    Edrey YH, Hanes M, Pinto M, Mele J, Buffenstein R.

    ILAR J. 2011 Feb 8;52(1):41-53.

    PMID:
    21411857
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Nrf2, a guardian of healthspan and gatekeeper of species longevity.

    Lewis KN, Mele J, Hayes JD, Buffenstein R.

    Integr Comp Biol. 2010 Nov;50(5):829-43. doi: 10.1093/icb/icq034. Epub 2010 May 6.

    PMID:
    21031035
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Endocrine function and neurobiology of the longest-living rodent, the naked mole-rat.

    Edrey YH, Park TJ, Kang H, Biney A, Buffenstein R.

    Exp Gerontol. 2011 Feb-Mar;46(2-3):116-23. doi: 10.1016/j.exger.2010.09.005. Epub 2010 Oct 1. Review.

    PMID:
    20888895
    [PubMed - indexed for MEDLINE]
    18.

    Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber).

    Liang S, Mele J, Wu Y, Buffenstein R, Hornsby PJ.

    Aging Cell. 2010 Aug;9(4):626-35. doi: 10.1111/j.1474-9726.2010.00588.x. Epub 2010 Jun 9.

    PMID:
    20550519
    [PubMed - indexed for MEDLINE]
    19.

    Lack of sexual dimorphism in femora of the eusocial and hypogonadic naked mole-rat: a novel animal model for the study of delayed puberty on the skeletal system.

    Pinto M, Jepsen KJ, Terranova CJ, Buffenstein R.

    Bone. 2010 Jan;46(1):112-20. doi: 10.1016/j.bone.2009.08.060. Epub 2009 Sep 15.

    PMID:
    19761882
    [PubMed - indexed for MEDLINE]
    20.

    The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.

    Buffenstein R, Edrey YH, Yang T, Mele J.

    Age (Dordr). 2008 Sep;30(2-3):99-109. doi: 10.1007/s11357-008-9058-z. Epub 2008 Jun 14.

    PMID:
    19424860
    [PubMed]
    Free PMC Article

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