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Items: 1 to 20 of 111

1.

Oxidative stress and life histories: unresolved issues and current needs.

Speakman JR, Blount JD, Bronikowski AM, Buffenstein R, Isaksson C, Kirkwood TB, Monaghan P, Ozanne SE, Beaulieu M, Briga M, Carr SK, Christensen LL, Cochemé HM, Cram DL, Dantzer B, Harper JM, Jurk D, King A, Noguera JC, Salin K, Sild E, Simons MJ, Smith S, Stier A, Tobler M, Vitikainen E, Peaker M, Selman C.

Ecol Evol. 2015 Nov 17;5(24):5745-57. doi: 10.1002/ece3.1790. eCollection 2015 Dec.

2.

Homology cluster differential expression analysis for interspecies mRNA-Seq experiments.

Gelfond JA, Ibrahim JG, Chen MH, Sun W, Lewis K, Kinahan S, Hibbs M, Buffenstein R.

Stat Appl Genet Mol Biol. 2015 Dec 1;14(6):507-16. doi: 10.1515/sagmb-2014-0056.

PMID:
26595407
3.

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity.

Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN.

Cell Rep. 2015 Nov 17;13(7):1319-26. doi: 10.1016/j.celrep.2015.10.014. Epub 2015 Nov 5.

4.

Multifactorial processes to slowing the biological clock: Insights from a comparative approach.

Sanchez JR, Milton SL, Corbit KC, Buffenstein R.

Exp Gerontol. 2015 Nov;71:27-37. doi: 10.1016/j.exger.2015.08.017. Epub 2015 Sep 4. Review.

PMID:
26343258
5.

Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax.

Li K, Hong W, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E, Zhao H.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11905-10. doi: 10.1073/pnas.1514896112. Epub 2015 Sep 4.

PMID:
26340990
6.

Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.

Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2213-24. doi: 10.1016/j.bbadis.2015.08.002. Epub 2015 Aug 4.

PMID:
26248058
7.

Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity.

Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN.

Cell Metab. 2015 Aug 4;22(2):332-43. doi: 10.1016/j.cmet.2015.07.005.

PMID:
26244935
8.

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA.

J Neurochem. 2015 Aug;134(3):538-50. doi: 10.1111/jnc.13149. Epub 2015 Jun 3.

PMID:
25940666
9.

Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.

Garbarino VR, Orr ME, Rodriguez KA, Buffenstein R.

Arch Biochem Biophys. 2015 Jun 15;576:8-16. doi: 10.1016/j.abb.2015.01.029. Epub 2015 Apr 1. Review.

PMID:
25841340
10.

Regulation of Nrf2 signaling and longevity in naturally long-lived rodents.

Lewis KN, Wason E, Edrey YH, Kristan DM, Nevo E, Buffenstein R.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3722-7. doi: 10.1073/pnas.1417566112. Epub 2015 Mar 9.

11.

Gene expression defines natural changes in mammalian lifespan.

Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN.

Aging Cell. 2015 Jun;14(3):352-65. doi: 10.1111/acel.12283. Epub 2015 Feb 9. Review.

12.

Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.

Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Pérez VI.

Biochem Biophys Res Commun. 2015 Feb 20;457(4):669-75. doi: 10.1016/j.bbrc.2015.01.046. Epub 2015 Jan 21.

PMID:
25615820
13.

Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.

Orr ME, Garbarino VR, Salinas A, Buffenstein R.

Neurobiol Aging. 2015 Mar;36(3):1496-504. doi: 10.1016/j.neurobiolaging.2014.12.004. Epub 2014 Dec 12.

PMID:
25576082
14.

Questioning the preclinical paradigm: natural, extreme biology as an alternative discovery platform.

Buffenstein R, Nelson OL, Corbit KC.

Aging (Albany NY). 2014 Nov;6(11):913-20. Review.

15.

Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.

Rodriguez KA, Dodds SG, Strong R, Galvan V, Sharp ZD, Buffenstein R.

Front Mol Neurosci. 2014 Nov 4;7:83. doi: 10.3389/fnmol.2014.00083. eCollection 2014.

16.

Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes.

Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, Bronson RT, Šumbera R, Buffenstein R, Zhou X, Krogh A, Park TJ, Zhang G, Wang J, Gladyshev VN.

Cell Rep. 2014 Sep 11;8(5):1354-64. doi: 10.1016/j.celrep.2014.07.030. Epub 2014 Aug 28.

17.

A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition.

Rodriguez KA, Osmulski PA, Pierce A, Weintraub ST, Gaczynska M, Buffenstein R.

Biochim Biophys Acta. 2014 Nov;1842(11):2060-72. doi: 10.1016/j.bbadis.2014.07.005. Epub 2014 Jul 10.

18.

And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat.

Grimes KM, Reddy AK, Lindsey ML, Buffenstein R.

Am J Physiol Heart Circ Physiol. 2014 Aug 1;307(3):H284-91. doi: 10.1152/ajpheart.00305.2014. Epub 2014 Jun 6.

19.

The first international mini-symposium on methionine restriction and lifespan.

Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N.

Front Genet. 2014 May 9;5:122. doi: 10.3389/fgene.2014.00122. eCollection 2014.

20.

Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.

Orr ME, Salinas A, Buffenstein R, Oddo S.

Neurobiol Aging. 2014 Jun;35(6):1233-42. doi: 10.1016/j.neurobiolaging.2013.12.006. Epub 2013 Dec 14.

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