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Items: 1 to 20 of 44

1.

Unanticipated role of melanin in causing carcinogenic cyclobutane pyrimidine dimmers.

Premi S, Brash DE.

Mol Cell Oncol. 2015 Jun 23;3(1):e1033588. doi: 10.1080/23723556.2015.1033588. eCollection 2016 Jan.

2.

Chemical excitation of electrons: A dark path to melanoma.

Premi S, Brash DE.

DNA Repair (Amst). 2016 Jun 1. pii: S1568-7864(16)30103-3. doi: 10.1016/j.dnarep.2016.05.023. [Epub ahead of print]

PMID:
27262612
3.

UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis.

Brash DE.

Toxicol Pathol. 2016 Jun;44(4):552-4. doi: 10.1177/0192623316632072. Epub 2016 Mar 7.

PMID:
26951162
4.

Cancer. Preprocancer.

Brash DE.

Science. 2015 May 22;348(6237):867-8. doi: 10.1126/science.aac4435. No abstract available.

PMID:
25999495
5.

Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Premi S, Wallisch S, Mano CM, Weiner AB, Bacchiocchi A, Wakamatsu K, Bechara EJ, Halaban R, Douki T, Brash DE.

Science. 2015 Feb 20;347(6224):842-7. doi: 10.1126/science.1256022.

6.

UV signature mutations.

Brash DE.

Photochem Photobiol. 2015 Jan-Feb;91(1):15-26. doi: 10.1111/php.12377. Epub 2014 Nov 28. Review.

7.

Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes.

Laurence M, Hatzis C, Brash DE.

PLoS One. 2014 May 16;9(5):e97876. doi: 10.1371/journal.pone.0097876. eCollection 2014.

8.

Clonal growth of human melanocytes using cell-free extracellular matrix.

Zhang R, Premi S, Kilic SS, Bacchiocchi A, Halaban R, Brash DE.

Pigment Cell Melanoma Res. 2013 Nov;26(6):925-7. doi: 10.1111/pcmr.12159. Epub 2013 Sep 19. No abstract available.

9.

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R.

Nat Genet. 2012 Sep;44(9):1006-14. doi: 10.1038/ng.2359. Epub 2012 Jul 29.

10.

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair.

Rochette PJ, Brash DE.

PLoS Genet. 2010 Apr 29;6(4):e1000926. doi: 10.1371/journal.pgen.1000926.

11.

Progressive apoptosis resistance prior to senescence and control by the anti-apoptotic protein BCL-xL.

Rochette PJ, Brash DE.

Mech Ageing Dev. 2008 Apr;129(4):207-14. doi: 10.1016/j.mad.2007.12.007. Epub 2008 Jan 4.

12.

Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling.

Knezevic D, Zhang W, Rochette PJ, Brash DE.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11286-91. Epub 2007 Jun 22.

13.

Roles of the transcription factor p53 in keratinocyte carcinomas.

Brash DE.

Br J Dermatol. 2006 May;154 Suppl 1:8-10. Review.

PMID:
16712710
14.

Colonization of adjacent stem cell compartments by mutant keratinocytes.

Brash DE, Zhang W, Grossman D, Takeuchi S.

Semin Cancer Biol. 2005 Apr;15(2):97-102. Review.

PMID:
15652454
15.

UVB-induced apoptosis drives clonal expansion during skin tumor development.

Zhang W, Hanks AN, Boucher K, Florell SR, Allen SM, Alexander A, Brash DE, Grossman D.

Carcinogenesis. 2005 Jan;26(1):249-57. Epub 2004 Oct 21.

16.

Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.

Takeuchi S, Zhang W, Wakamatsu K, Ito S, Hearing VJ, Kraemer KH, Brash DE.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15076-81. Epub 2004 Oct 11.

17.

Role of E2F1 in apoptosis: a case study in feedback loops.

Knezevic D, Brash DE.

Cell Cycle. 2004 Jun;3(6):729-32. Epub 2004 Jun 6. Review.

PMID:
15107604
18.

Creating knowledgebases to text-mine PUBMED articles using clustering techniques.

Crasto CJ, Morse TM, Migliore M, Nadkarni P, Hines M, Brash DE, Miller PL, Shepherd GM.

AMIA Annu Symp Proc. 2003:821.

19.

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

Remenyik E, Wikonkál NM, Zhang W, Paliwal V, Brash DE.

Oncogene. 2003 Sep 25;22(41):6369-76.

PMID:
14508517
20.

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE.

Nat Cell Biol. 2003 Jul;5(7):655-60.

PMID:
12833065
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