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Results: 1 to 20 of 40

1.

Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Premi S, Wallisch S, Mano CM, Weiner AB, Bacchiocchi A, Wakamatsu K, Bechara EJ, Halaban R, Douki T, Brash DE.

Science. 2015 Feb 20;347(6224):842-7. doi: 10.1126/science.1256022.

PMID:
25700512
[PubMed - in process]
2.

UV signature mutations.

Brash DE.

Photochem Photobiol. 2015 Jan-Feb;91(1):15-26. doi: 10.1111/php.12377. Epub 2014 Nov 28.

PMID:
25354245
[PubMed - in process]
3.

Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes.

Laurence M, Hatzis C, Brash DE.

PLoS One. 2014 May 16;9(5):e97876. doi: 10.1371/journal.pone.0097876. eCollection 2014.

PMID:
24837716
[PubMed - in process]
Free PMC Article
4.

Clonal growth of human melanocytes using cell-free extracellular matrix.

Zhang R, Premi S, Kilic SS, Bacchiocchi A, Halaban R, Brash DE.

Pigment Cell Melanoma Res. 2013 Nov;26(6):925-7. doi: 10.1111/pcmr.12159. Epub 2013 Sep 19. No abstract available.

PMID:
24034857
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R.

Nat Genet. 2012 Sep;44(9):1006-14. doi: 10.1038/ng.2359. Epub 2012 Jul 29.

PMID:
22842228
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair.

Rochette PJ, Brash DE.

PLoS Genet. 2010 Apr 29;6(4):e1000926. doi: 10.1371/journal.pgen.1000926.

PMID:
20442874
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Progressive apoptosis resistance prior to senescence and control by the anti-apoptotic protein BCL-xL.

Rochette PJ, Brash DE.

Mech Ageing Dev. 2008 Apr;129(4):207-14. doi: 10.1016/j.mad.2007.12.007. Epub 2008 Jan 4.

PMID:
18262222
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling.

Knezevic D, Zhang W, Rochette PJ, Brash DE.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11286-91. Epub 2007 Jun 22.

PMID:
17586682
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Roles of the transcription factor p53 in keratinocyte carcinomas.

Brash DE.

Br J Dermatol. 2006 May;154 Suppl 1:8-10. Review.

PMID:
16712710
[PubMed - indexed for MEDLINE]
10.

Colonization of adjacent stem cell compartments by mutant keratinocytes.

Brash DE, Zhang W, Grossman D, Takeuchi S.

Semin Cancer Biol. 2005 Apr;15(2):97-102. Review.

PMID:
15652454
[PubMed - indexed for MEDLINE]
11.

UVB-induced apoptosis drives clonal expansion during skin tumor development.

Zhang W, Hanks AN, Boucher K, Florell SR, Allen SM, Alexander A, Brash DE, Grossman D.

Carcinogenesis. 2005 Jan;26(1):249-57. Epub 2004 Oct 21.

PMID:
15498793
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.

Takeuchi S, Zhang W, Wakamatsu K, Ito S, Hearing VJ, Kraemer KH, Brash DE.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15076-81. Epub 2004 Oct 11.

PMID:
15477596
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Role of E2F1 in apoptosis: a case study in feedback loops.

Knezevic D, Brash DE.

Cell Cycle. 2004 Jun;3(6):729-32. Epub 2004 Jun 6. Review.

PMID:
15107604
[PubMed - indexed for MEDLINE]
Free Article
14.

Creating knowledgebases to text-mine PUBMED articles using clustering techniques.

Crasto CJ, Morse TM, Migliore M, Nadkarni P, Hines M, Brash DE, Miller PL, Shepherd GM.

AMIA Annu Symp Proc. 2003:821.

PMID:
14728326
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

Remenyik E, Wikonkál NM, Zhang W, Paliwal V, Brash DE.

Oncogene. 2003 Sep 25;22(41):6369-76.

PMID:
14508517
[PubMed - indexed for MEDLINE]
16.

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE.

Nat Cell Biol. 2003 Jul;5(7):655-60.

PMID:
12833065
[PubMed - indexed for MEDLINE]
17.

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.

Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T, Yang DD, Eynon E, Brash DE, Kashgarian M, Flavell RA, Wolin SL.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7503-8. Epub 2003 Jun 3.

PMID:
12788971
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

New careers for antioxidants.

Brash DE, Havre PA.

Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):13969-71. Epub 2002 Oct 21. Review. No abstract available.

PMID:
12391310
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.

Havre PA, O'Reilly S, McCormick JJ, Brash DE.

Cancer Res. 2002 Mar 1;62(5):1443-9.

PMID:
11888918
[PubMed - indexed for MEDLINE]
Free Article
20.

The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes.

Brash DE, Wikonkal NM, Remenyik E, van der Horst GT, Friedberg EC, Cheo DL, van Steeg H, Westerman A, van Kranen HJ.

J Invest Dermatol. 2001 Nov;117(5):1234-40.

PMID:
11710938
[PubMed - indexed for MEDLINE]
Free Article
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