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Items: 1 to 20 of 248

1.

Metformin-induced mitochondrial function and ABCD2 up regulation in X-linked adrenoleukodystrophy involves AMP activated protein kinase.

Singh J, Olle B, Suhail H, Felicella MM, Giri S.

J Neurochem. 2016 Feb 5. doi: 10.1111/jnc.13562. [Epub ahead of print]

PMID:
26849413
2.

GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial.

Farr OM, Sofopoulos M, Tsoukas MA, Dincer F, Thakkar B, Sahin-Efe A, Filippaios A, Bowers J, Srnka A, Gavrieli A, Ko BJ, Liakou C, Kanyuch N, Tseleni-Balafouta S, Mantzoros CS.

Diabetologia. 2016 Feb 1. [Epub ahead of print]

PMID:
26831302
3.

Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic review.

Bo QJ, Wang ZM, Li XB, Ma X, Wang CY, de Leon J.

Psychiatry Res. 2016 Jan 16. pii: S0165-1781(16)30083-X. doi: 10.1016/j.psychres.2016.01.031. [Epub ahead of print]

PMID:
26822064
4.

Metformin treatment of antipsychotic-induced dyslipidemia: an analysis of two randomized, placebo-controlled trials.

Wu RR, Zhang FY, Gao KM, Ou JJ, Shao P, Jin H, Guo WB, Chan PK, Zhao JP.

Mol Psychiatry. 2016 Jan 26. doi: 10.1038/mp.2015.221. [Epub ahead of print]

PMID:
26809842
5.

Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53.

Song YM, Lee WK, Lee YH, Kang ES, Cha BS, Lee BW.

Int J Mol Sci. 2016 Jan 16;17(1). pii: E122. doi: 10.3390/ijms17010122.

6.

Influence of metformin on mitochondrial subproteome in the brain of apoE knockout mice.

Suski M, Olszanecki R, Chmura Ł, Stachowicz A, Madej J, Okoń K, Adamek D, Korbut R.

Eur J Pharmacol. 2016 Feb 5;772:99-107. doi: 10.1016/j.ejphar.2015.12.036. Epub 2015 Dec 19.

PMID:
26712380
7.

HL271, a novel chemical compound derived from metformin, differs from metformin in its effects on the circadian clock and metabolism.

Row H, Jeong J, Cho S, Kim S, Kim K.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):783-9. doi: 10.1016/j.bbrc.2015.11.069. Epub 2015 Dec 18.

PMID:
26707879
8.

Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice.

Allard JS, Perez EJ, Fukui K, Carpenter P, Ingram DK, Cabo Rd.

Behav Brain Res. 2016 Mar 15;301:1-9. doi: 10.1016/j.bbr.2015.12.012. Epub 2015 Dec 14.

PMID:
26698400
9.

AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.

Vázquez-Manrique RP, Farina F, Cambon K, Sequedo MD, Parker AJ, Millán JM, Weiss A, Déglon N, Neri C.

Hum Mol Genet. 2015 Dec 17. pii: ddv513. [Epub ahead of print]

10.

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation.

Fatt M, Hsu K, He L, Wondisford F, Miller FD, Kaplan DR, Wang J.

Stem Cell Reports. 2015 Dec 8;5(6):988-95. doi: 10.1016/j.stemcr.2015.10.014. Epub 2015 Nov 19.

11.

Drug repurposing for immune modulation in acute ischemic stroke.

Amantea D, Bagetta G.

Curr Opin Pharmacol. 2016 Feb;26:124-30. doi: 10.1016/j.coph.2015.11.006. Epub 2015 Dec 1. Review.

PMID:
26657075
12.

Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats.

Argun M, Üzüm K, Sönmez MF, Özyurt A, Karabulut D, Soyersarıca Z, Çilenk KT, Unalmış S, Pamukcu Ö, Baykan A, Narin F, Elmalı F, Narin N.

Anatol J Cardiol. 2015 Apr 30. doi: 10.5152/akd.2015.6185. [Epub ahead of print]

PMID:
26642465
13.

Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells.

Mouhieddine TH, Nokkari A, Itani MM, Chamaa F, Bahmad H, Monzer A, El-Merahbi R, Daoud G, Eid A, Kobeissy FH, Abou-Kheir W.

Front Neurosci. 2015 Nov 23;9:442. doi: 10.3389/fnins.2015.00442. eCollection 2015.

14.

The effect of metformin on neuronal activity in the appetite-regulating brain regions of mice fed a high-fat diet during an anorectic period.

Kim HJ, Jin BY, Oh MJ, Shin KH, Choi SH, Kim DH.

Physiol Behav. 2016 Feb 1;154:184-90. doi: 10.1016/j.physbeh.2015.11.028. Epub 2015 Nov 26.

PMID:
26631545
15.

Linagliptin attenuates diabetes-induced cerebral pathological neovascularization in a blood glucose-independent manner: Potential role of ET-1.

Abdelsaid M, Williams R, Hardigan T, Ergul A.

Life Sci. 2015 Nov 26. pii: S0024-3205(15)30090-4. doi: 10.1016/j.lfs.2015.11.026. [Epub ahead of print]

PMID:
26631506
16.
17.

Author Response.

Fernandes GC, Rieder CR, Vedolin L, Campos L, Koltermann T.

Neurology. 2015 Aug 18;85(7):655. No abstract available.

PMID:
26505051
18.

Preventing Allograft Rejection by Targeting Immune Metabolism.

Lee CF, Lo YC, Cheng CH, Furtmüller GJ, Oh B, Andrade-Oliveira V, Thomas AG, Bowman CE, Slusher BS, Wolfgang MJ, Brandacher G, Powell JD.

Cell Rep. 2015 Oct 27;13(4):760-70. doi: 10.1016/j.celrep.2015.09.036. Epub 2015 Oct 17.

19.

The Antidiabetic Drug Metformin Stimulates Glycolytic Lactate Production in Cultured Primary Rat Astrocytes.

Westhaus A, Blumrich EM, Dringen R.

Neurochem Res. 2015 Oct 3. [Epub ahead of print]

PMID:
26433380
20.

Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.

Yu Z, Zhao G, Xie G, Zhao L, Chen Y, Yu H, Zhang Z, Li C, Li Y.

Oncotarget. 2015 Oct 20;6(32):32930-43. doi: 10.18632/oncotarget.5405.

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