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Page 1
Pregnancy and the biliary tract.
Gilat T, Konikoff F. Gilat T, et al. Can J Gastroenterol. 2000 Nov;14 Suppl D:55D-59D. doi: 10.1155/2000/932147. Can J Gastroenterol. 2000. PMID: 11110613 Review.
Some 20% to 30% of these gallstones redissolve postpartum. The frequency of biliary colic during pregnancy is controversial, and the recommended therapeutic approach during pregnancy is conservative. When essential, invasive procedures are relatively well tolerated, …
Some 20% to 30% of these gallstones redissolve postpartum. The frequency of biliary colic during pregnancy is controversial, a …
An Update on the Lithogenic Mechanisms of Cholecystokinin a Receptor (CCKAR), an Important Gallstone Gene for Lith13.
Wang HH, Portincasa P, Liu M, Tso P, Wang DQ. Wang HH, et al. Genes (Basel). 2020 Nov 29;11(12):1438. doi: 10.3390/genes11121438. Genes (Basel). 2020. PMID: 33260332 Free PMC article. Review.
Dysfunctional gallbladder emptying in response to exogenously administered CCK-8 is often found in patients with cholesterol gallstones, and patients with pigment gallstones display an intermediate degree of gallbladder motility defect. ...The physical-chemical, gen …
Dysfunctional gallbladder emptying in response to exogenously administered CCK-8 is often found in patients with cholesterol gallstones …
G Protein-Coupled Estrogen Receptor, GPER1, Offers a Novel Target for the Treatment of Digestive Diseases.
DeLeon C, Wang DQ, Arnatt CK. DeLeon C, et al. Front Endocrinol (Lausanne). 2020 Nov 12;11:578536. doi: 10.3389/fendo.2020.578536. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33281743 Free PMC article. Review.
There are gender differences between men and women in many physiological functions and diseases, which indicates that female sex hormones may be important. ...More recently, research found that GPER1 may play an important role in regulating the digestive system. Cholestero …
There are gender differences between men and women in many physiological functions and diseases, which indicates that female sex horm …
Genetic Analysis of ABCB4 Mutations and Variants Related to the Pathogenesis and Pathophysiology of Low Phospholipid-Associated Cholelithiasis.
Wang HH, Portincasa P, Liu M, Wang DQ. Wang HH, et al. Genes (Basel). 2022 Jun 11;13(6):1047. doi: 10.3390/genes13061047. Genes (Basel). 2022. PMID: 35741809 Free PMC article. Review.
The main features of LPAC include a reduction or deficiency of phospholipids in bile, symptomatic cholelithiasis at <40 years of age, intrahepatic sludge and microlithiasis, mild chronic cholestasis, a high cholesterol/phospholipid ratio in bile, and recur …
The main features of LPAC include a reduction or deficiency of phospholipids in bile, symptomatic cholelithiasis at <40 years of a …
Update on the Molecular Mechanisms Underlying the Effect of Cholecystokinin and Cholecystokinin-1 Receptor on the Formation of Cholesterol Gallstones.
Wang HH, Portincasa P, Wang DQ. Wang HH, et al. Curr Med Chem. 2019;26(19):3407-3423. doi: 10.2174/0929867324666170619104801. Curr Med Chem. 2019. PMID: 28625150 Free PMC article. Review.
Disruption of the Cck or the Cck-1r gene in mice significantly increases the formation of cholesterol gallstones by disrupting gallbladder emptying and biliary cholesterol metabolism, as well as promoting intestinal absorption of cholesterol. Abnormalities in gallbl …
Disruption of the Cck or the Cck-1r gene in mice significantly increases the formation of cholesterol gallstones by disrupting gallbl …
Impaired gallbladder motility and delayed orocecal transit contribute to pigment gallstone and biliary sludge formation in beta-thalassemia major adults.
Portincasa P, Moschetta A, Berardino M, Di-Ciaula A, Vacca M, Baldassarre G, Pietrapertosa A, Cammarota R, Tannoia N, Palasciano G. Portincasa P, et al. World J Gastroenterol. 2004 Aug 15;10(16):2383-90. doi: 10.3748/wjg.v10.i16.2383. World J Gastroenterol. 2004. PMID: 15285024 Free PMC article.
Gallbladder content (ultrasonography) was examined before and during 8-12 mo follow-up. RESULTS: Gallstones and/or biliary sludge were found in 13 (56%) patients. beta-thalassemia major patients had increased fasting (38.0+/-4.8 mL vs 20.3+/-0.7 mL, P = 0.000 …
Gallbladder content (ultrasonography) was examined before and during 8-12 mo follow-up. RESULTS: Gallstones and/or biliary …
Human gallbladder mucosal function. Effect of concentration and acidification of bile on cholesterol and calcium solubility.
Shiffman ML, Sugerman HJ, Moore EW. Shiffman ML, et al. Gastroenterology. 1990 Nov;99(5):1452-9. doi: 10.1016/0016-5085(90)91175-6. Gastroenterology. 1990. PMID: 2210252
All had negative results of intra-operative ultrasound examinations for sludge and gallstones, normal liver function tests, and no history of hepatobiliary disease. ...As bile was concentrated, cholesterol saturation index decreased curvilinearly from a maxim …
All had negative results of intra-operative ultrasound examinations for sludge and gallstones, normal liver function tests, an …
Parenteral nutrition-induced hepatobiliary dysfunction in infants and prepubertal rabbits.
Loff S, Kränzlin B, Moghadam M, Dzakovic A, Wessel L, Back W, Hosie S, Wirth H, Waag KL. Loff S, et al. Pediatr Surg Int. 1999;15(7):479-82. doi: 10.1007/s003830050643. Pediatr Surg Int. 1999. PMID: 10525903
A rise in bilirubin and aminotransferase levels occurred after a minimum of 5 weeks; peak bilirubin levels ranged from 4 to 14 mg% and aminotransferases from 40 to 140 IU/l. One child later developed gallstones. Liver biopsies after 1 to 24 months showed fibrosis, bile …
A rise in bilirubin and aminotransferase levels occurred after a minimum of 5 weeks; peak bilirubin levels ranged from 4 to 14 mg% and amino …
Dietary induction of cholesterol gallstones in the owl monkey: preliminary findings in a new animal model.
Pekow CA, Weller RE, Schulte SJ, Lee SP. Pekow CA, et al. Lab Anim Sci. 1995 Dec;45(6):657-62. Lab Anim Sci. 1995. PMID: 8746526
The owl monkey (Aotus nancymae) is a primate with a bile acid and biliary lipid profile resembling that of humans. Aotus spp. are among the rare species, including humans, that spontaneously develop cholesterol gallstones. ...This model can provide sequential …
The owl monkey (Aotus nancymae) is a primate with a bile acid and biliary lipid profile resembling that of humans. Aotus spp. …