Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 39


Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension.

Bruder-Nascimento T, Butler BR, Herren DJ, Brands MW, Bence KK, Belin de Chantemèle EJ.

Pharmacol Res. 2015 Oct 30;102:235-244. doi: 10.1016/j.phrs.2015.10.012. [Epub ahead of print]


Leptin and insulin act on POMC neurons to promote the browning of white fat.

Dodd GT, Decherf S, Loh K, Simonds SE, Wiede F, Balland E, Merry TL, Münzberg H, Zhang ZY, Kahn BB, Neel BG, Bence KK, Andrews ZB, Cowley MA, Tiganis T.

Cell. 2015 Jan 15;160(1-2):88-104. doi: 10.1016/j.cell.2014.12.022.


Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling.

Ozek C, Kanoski SE, Zhang ZY, Grill HJ, Bence KK.

J Biol Chem. 2014 Nov 14;289(46):31682-92. doi: 10.1074/jbc.M114.603621. Epub 2014 Oct 6.


Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis.

Lim MA, Bence KK, Sandesara I, Andreux P, Auwerx J, Ishibashi J, Seale P, Kalb RG.

Hum Mol Genet. 2014 Sep 15;23(18):4995-5008. doi: 10.1093/hmg/ddu214. Epub 2014 May 15.


Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.

Tsou RC, Rak KS, Zimmer DJ, Bence KK.

Mol Metab. 2014 Jan 19;3(3):301-12. doi: 10.1016/j.molmet.2014.01.008. eCollection 2014 Jun.


Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice.

Owen C, Lees EK, Grant L, Zimmer DJ, Mody N, Bence KK, Delibegović M.

Diabetologia. 2013 Oct;56(10):2286-96. doi: 10.1007/s00125-013-2992-z. Epub 2013 Jul 6.


Central regulation of metabolism by protein tyrosine phosphatases.

Tsou RC, Bence KK.

Front Neurosci. 2013 Jan 7;6:192. doi: 10.3389/fnins.2012.00192. eCollection 2012.


Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B.

Koss DJ, Riedel G, Bence K, Platt B.

Cell Calcium. 2013 Feb;53(2):125-38. doi: 10.1016/j.ceca.2012.11.004. Epub 2012 Dec 4.


Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies.

Carbone CJ, Zheng H, Bhattacharya S, Lewis JR, Reiter AM, Henthorn P, Zhang ZY, Baker DP, Ukkiramapandian R, Bence KK, Fuchs SY.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19226-31. doi: 10.1073/pnas.1211491109. Epub 2012 Nov 5.


Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.

Fuentes F, Zimmer D, Atienza M, Schottenfeld J, Penkala I, Bale T, Bence KK, Arregui CO.

PLoS One. 2012;7(7):e41536. doi: 10.1371/journal.pone.0041536. Epub 2012 Jul 23.


The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency.

Tsou RC, Bence KK.

J Obes. 2012;2012:926857. doi: 10.1155/2012/926857. Epub 2012 Jul 1.


Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.

Tsou RC, Zimmer DJ, De Jonghe BC, Bence KK.

Endocrinology. 2012 Sep;153(9):4227-37. doi: 10.1210/en.2012-1548. Epub 2012 Jul 16.


Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.

De Jonghe BC, Hayes MR, Zimmer DJ, Kanoski SE, Grill HJ, Bence KK.

Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E644-51. doi: 10.1152/ajpendo.00009.2012. Epub 2012 Jul 3.


Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals.

Kanoski SE, Zhao S, Guarnieri DJ, DiLeone RJ, Yan J, De Jonghe BC, Bence KK, Hayes MR, Grill HJ.

Am J Physiol Endocrinol Metab. 2012 Aug 15;303(4):E496-503. doi: 10.1152/ajpendo.00205.2012. Epub 2012 Jun 12.


Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.

Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, Mcilroy GD, Göransson O, Welch A, Bence KK, Kahn BB, Neel BG, Mody N, Delibegović M.

PLoS One. 2012;7(2):e32700. doi: 10.1371/journal.pone.0032700. Epub 2012 Feb 28.


Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.

Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T.

Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Erratum in: Cell Metab. 2012 Jun 6;15(6):925-6.


Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.

Balavenkatraman KK, Aceto N, Britschgi A, Mueller U, Bence KK, Neel BG, Bentires-Alj M.

Mol Cancer Res. 2011 Oct;9(10):1377-84. doi: 10.1158/1541-7786.MCR-11-0198. Epub 2011 Aug 17.


Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress.

Agouni A, Mody N, Owen C, Czopek A, Zimmer D, Bentires-Alj M, Bence KK, Delibegović M.

Biochem J. 2011 Sep 1;438(2):369-78. doi: 10.1042/BJ20110373.


Melanocortin control of energy balance: evidence from rodent models.

De Jonghe BC, Hayes MR, Bence KK.

Cell Mol Life Sci. 2011 Aug;68(15):2569-88. doi: 10.1007/s00018-011-0707-5. Epub 2011 May 8. Review.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk