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Year Number of Results
2010 2
2011 1
2012 1
2013 1
2014 3
2015 3
2016 4
2017 6
2018 4
2019 6
2020 4
2021 3
2022 1
2023 2
2024 1

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36 results

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Page 1
Diagnosis and Management of Severe Asthma.
Chung KF. Chung KF. Semin Respir Crit Care Med. 2018 Feb;39(1):91-99. doi: 10.1055/s-0037-1607391. Epub 2018 Feb 10. Semin Respir Crit Care Med. 2018. PMID: 29427989 Review.
Patients who usually present with 'difficult-to-treat asthma' should first be assessed to determine whether he/she has asthma with the exclusion of other diagnoses and if so, whether the asthma can be classified as severe therapy-resistant. ...Further progres …
Patients who usually present with 'difficult-to-treat asthma' should first be assessed to determine whether he/she has asthma …
Cost-Effectiveness of Bronchial Thermoplasty, Omalizumab, and Standard Therapy for Moderate-to-Severe Allergic Asthma.
Zafari Z, Sadatsafavi M, Marra CA, Chen W, FitzGerald JM. Zafari Z, et al. PLoS One. 2016 Jan 11;11(1):e0146003. doi: 10.1371/journal.pone.0146003. eCollection 2016. PLoS One. 2016. PMID: 26751790 Free PMC article.
BACKGROUND: Bronchial thermoplasty (BT) is a recently developed treatment for patients with moderate-to-severe asthma. ...However, no study has evaluated the cost-effectiveness of BT compared to other alternative treatments for moderate-to-severe allergic …
BACKGROUND: Bronchial thermoplasty (BT) is a recently developed treatment for patients with moderate-to-severe asthma. …
Bronchial thermoplasty and biological therapy as targeted treatments for severe uncontrolled asthma.
Trivedi A, Pavord ID, Castro M. Trivedi A, et al. Lancet Respir Med. 2016 Jul;4(7):585-592. doi: 10.1016/S2213-2600(16)30018-2. Epub 2016 May 24. Lancet Respir Med. 2016. PMID: 27230825 Review.
Omalizumab, a monoclonal antibody to IgE, improves asthma control in patients with a predominant allergic phenotype. ...Bronchial thermoplasty, a new technique to reduce airway smooth muscle mass, improves symptoms and reduces exacerbations in patients …
Omalizumab, a monoclonal antibody to IgE, improves asthma control in patients with a predominant allergic phenotype. ...Bro …
Precision medicine in asthma: the role of bronchial thermoplasty.
Oberle AJ, Mathur P. Oberle AJ, et al. Curr Opin Pulm Med. 2017 May;23(3):254-260. doi: 10.1097/MCP.0000000000000372. Curr Opin Pulm Med. 2017. PMID: 28319473 Review.
Bronchial thermoplasty has emerged as an option for the treatment of severe asthma. SUMMARY: The appropriate selection of patients through the use of eosinophilic biomarkers has led to significant reductions in exacerbations with the use of mAb therapy. Br …
Bronchial thermoplasty has emerged as an option for the treatment of severe asthma. SUMMARY: The appropriate selection …
Bronchial Thermoplasty for Severe Asthma: A Review of the Clinical and Cost-Effectiveness, and Guidelines.
[No authors listed] [No authors listed] Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Aug 27. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Aug 27. PMID: 26985548 Free Books & Documents. Review.
The standard approach to care employs regular maintenance medications, usually inhaled corticosteroids (ICS) and a long-acting beta(2)-agonist (LABA), while other medications may also be used including omalizumab and oral corticosteroids. Bronchial thermoplasty …
The standard approach to care employs regular maintenance medications, usually inhaled corticosteroids (ICS) and a long-acting beta(2)-agoni …
Indirect comparison of bronchial thermoplasty versus omalizumab for uncontrolled severe asthma.
Niven RM, Simmonds MR, Cangelosi MJ, Tilden DP, Cottrell S, Shargill NS. Niven RM, et al. J Asthma. 2018 Apr;55(4):443-451. doi: 10.1080/02770903.2017.1337789. Epub 2017 Jul 14. J Asthma. 2018. PMID: 28708944
OBJECTIVE: Bronchial thermoplasty (BT) as an add-on therapy for uncontrolled severe asthma is an alternative to biologic therapies like omalizumab (OM). ...However, based on the analysis, BT compares well with a potentially more costly pharmacotherapy …
OBJECTIVE: Bronchial thermoplasty (BT) as an add-on therapy for uncontrolled severe asthma is an alternative to biologi …
Role of clinical biomarkers in predicting the effectiveness of omalizumab.
Zhang Q, Li C, Wan J, Zhang M, Nong Y, Lin J. Zhang Q, et al. Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231170821. doi: 10.1177/17534666231170821. Ther Adv Respir Dis. 2023. PMID: 37148201 Free PMC article.
OBJECTIVE: To explore whether baseline clinical biomarkers and characteristics can be used to predict the responsiveness of omalizumab. METHODS: We retrospectively analyzed a cohort of patients with severe asthma who received omalizumab treatment and collecte …
OBJECTIVE: To explore whether baseline clinical biomarkers and characteristics can be used to predict the responsiveness of omalizumab …
Refractory asthma - beyond step 5, the role of new and emerging adjuvant therapies.
Kane B, Fowler SJ, Niven R. Kane B, et al. Chron Respir Dis. 2015 Feb;12(1):69-77. doi: 10.1177/1479972314562210. Epub 2014 Dec 9. Chron Respir Dis. 2015. PMID: 25492977 Free article. Review.
A small percentage of asthmatics have 'severe refractory asthma', where there is suboptimal response to currently available therapies. ...This review article outlines new and emerging treatments for severe asthma, including monoclonal antibodies targeting eosinophil …
A small percentage of asthmatics have 'severe refractory asthma', where there is suboptimal response to currently available therapies …
Clinical and histopathologic predictors of therapeutic response to bronchial thermoplasty in severe refractory asthma.
Ladjemi MZ, Di Candia L, Heddebaut N, Techoueyres C, Airaud E, Soussan D, Dombret MC, Hamidi F, Guillou N, Mordant P, Castier Y, Létuvé S, Taillé C, Aubier M, Pretolani M. Ladjemi MZ, et al. J Allergy Clin Immunol. 2021 Nov;148(5):1227-1235.e6. doi: 10.1016/j.jaci.2020.12.642. Epub 2021 Jan 13. J Allergy Clin Immunol. 2021. PMID: 33453288
BACKGROUND: Phenotypes and endotypes predicting optimal response to bronchial thermoplasty (BT) in patients with severe asthma remain elusive. OBJECTIVE: Our aim was to compare the clinical characteristics and hallmarks of airway inflammation and remodeling b …
BACKGROUND: Phenotypes and endotypes predicting optimal response to bronchial thermoplasty (BT) in patients with severe ast …
The Impact of Bronchial Thermoplasty on Asthma-Related Quality of Life and Controller Medication Use.
Seeley EJ, Alshelli I, Canfield J, Lum M, Krishna G. Seeley EJ, et al. Respiration. 2019;98(2):165-170. doi: 10.1159/000499404. Epub 2019 May 2. Respiration. 2019. PMID: 31048594
Bronchial thermoplasty (BT) utilizes thermal energy to reduce airway smooth muscle. ...Patients treated with BT showed a reduction in the use of montelukast and omalizumab 1 year after BT. CONCLUSION: In patients with severe persistent asthma and low …
Bronchial thermoplasty (BT) utilizes thermal energy to reduce airway smooth muscle. ...Patients treated with BT showed a reduc …
36 results