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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 2
1975 1
1976 1
1979 1
1980 1
1989 1
1990 1
1997 2
1998 2
2000 2
2002 3
2003 3
2004 5
2005 4
2006 7
2007 9
2008 3
2009 12
2010 14
2011 12
2012 14
2013 17
2014 20
2015 19
2016 15
2017 19
2018 16
2019 13
2020 20
2021 17
2022 18
2023 17
2024 8

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274 results

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Page 1
Characteristics, phenotypes, mechanisms and management of severe asthma.
Chung KF, Dixey P, Abubakar-Waziri H, Bhavsar P, Patel PH, Guo S, Ji Y. Chung KF, et al. Chin Med J (Engl). 2022 May 20;135(10):1141-1155. doi: 10.1097/CM9.0000000000001990. Chin Med J (Engl). 2022. PMID: 35633594 Free PMC article. Review.
Molecular phenotyping has also revealed non-T2 inflammatory phenotypes such as Type-1 or Type-17 driven phenotypes. ...The future lies with molecular phenotyping of the airway inflammatory process to refine asthma endotypes for precision …
Molecular phenotyping has also revealed non-T2 inflammatory phenotypes such as Type-1 or Type-17 driven phenotypes. ... …
COPD Phenotyping.
Christenson SA. Christenson SA. Respir Care. 2023 Jul;68(7):871-880. doi: 10.4187/respcare.11035. Respir Care. 2023. PMID: 37353326 Review.
In such a complex chronic disease, phenotyping individuals based on similar clinical or molecular characteristics can aid in guiding appropriate therapeutic management. ...This review summarizes the evolution of COPD phenotyping, the current use of …
In such a complex chronic disease, phenotyping individuals based on similar clinical or molecular characteristics can a …
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH; SpiroMeta Consortium; International COPD Genetics Consortium. Sakornsakolpat P, et al. Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25. Nat Genet. 2019. PMID: 30804561 Free PMC article.
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide association study in 35,735 cases and 222,076 cont …
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic ri …
Pulmonary function testing.
Ruppel GL, Enright PL. Ruppel GL, et al. Respir Care. 2012 Jan;57(1):165-75. doi: 10.4187/respcare.01640. Respir Care. 2012. PMID: 22222135 Free article. Review.
Pulmonary function testing is often considered the basis for diagnosis in many categories of pulmonary disease. ...These topics included testing of adults and children, with concentration on important disease entities such as COPD, asthma, and u …
Pulmonary function testing is often considered the basis for diagnosis in many categories of pulmonary disease. ...Thes …
Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study.
Maselli DJ, Bhatt SP, Anzueto A, Bowler RP, DeMeo DL, Diaz AA, Dransfield MT, Fawzy A, Foreman MG, Hanania NA, Hersh CP, Kim V, Kinney GL, Putcha N, Wan ES, Wells JM, Westney GE, Young KA, Silverman EK, Han MK, Make BJ. Maselli DJ, et al. Chest. 2019 Aug;156(2):228-238. doi: 10.1016/j.chest.2019.04.135. Epub 2019 May 30. Chest. 2019. PMID: 31154041 Free PMC article. Review.
The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter, longitudinal analysis of > 10,000 subjects, including smokers with a 10 pack-year history with and without COPD and healthy never smokers. The goal was to characterize disease-related …
The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter, longitudinal analysis of > 10,000 subjects, includ …
Macrophages: Their role, activation and polarization in pulmonary diseases.
Arora S, Dev K, Agarwal B, Das P, Syed MA. Arora S, et al. Immunobiology. 2018 Apr-May;223(4-5):383-396. doi: 10.1016/j.imbio.2017.11.001. Epub 2017 Nov 12. Immunobiology. 2018. PMID: 29146235 Free PMC article. Review.
Two hallmarks of macrophages are diversity and plasticity due to which they acquire a wobbling array of phenotypes. These phenotypes are appropriately synchronized responses to a variety of different stimuli from either the tissue microenvironment or - microbes or t …
Two hallmarks of macrophages are diversity and plasticity due to which they acquire a wobbling array of phenotypes. These phenotyp …
Azithromycin: mechanisms of action and their relevance for clinical applications.
Parnham MJ, Erakovic Haber V, Giamarellos-Bourboulis EJ, Perletti G, Verleden GM, Vos R. Parnham MJ, et al. Pharmacol Ther. 2014 Aug;143(2):225-45. doi: 10.1016/j.pharmthera.2014.03.003. Epub 2014 Mar 11. Pharmacol Ther. 2014. PMID: 24631273 Review.
Modulation of host responses facilitates its long-term therapeutic benefit in cystic fibrosis, non-cystic fibrosis bronchiectasis, exacerbations of chronic obstructive pulmonary disease (COPD) and non-eosinophilic asthma. ...Delayed inhibitory e …
Modulation of host responses facilitates its long-term therapeutic benefit in cystic fibrosis, non-cystic fibrosis bronchiectasis, exacerbat …
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline.
Holguin F, Cardet JC, Chung KF, Diver S, Ferreira DS, Fitzpatrick A, Gaga M, Kellermeyer L, Khurana S, Knight S, McDonald VM, Morgan RL, Ortega VE, Rigau D, Subbarao P, Tonia T, Adcock IM, Bleecker ER, Brightling C, Boulet LP, Cabana M, Castro M, Chanez P, Custovic A, Djukanovic R, Frey U, Frankemölle B, Gibson P, Hamerlijnck D, Jarjour N, Konno S, Shen H, Vitary C, Bush A. Holguin F, et al. Eur Respir J. 2020 Jan 2;55(1):1900588. doi: 10.1183/13993003.00588-2019. Print 2020 Jan. Eur Respir J. 2020. PMID: 31558662 Free article.
The evidence syntheses were discussed and recommendations formulated by a multidisciplinary Task Force of asthma experts, who made specific recommendations on six specific questions. After considering the balance of desirable and undesirable consequences, quality of eviden …
The evidence syntheses were discussed and recommendations formulated by a multidisciplinary Task Force of asthma experts, who made sp …
Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease.
Guyatt A, John C, Williams AT, Shrine N, Reeve NF; SpiroMeta consortium; Sayers I, Hall I, Wain LV, Sheehan N, Dudbridge F, Tobin MD. Guyatt A, et al. Thorax. 2023 May;78(5):496-503. doi: 10.1136/thoraxjnl-2021-217993. Epub 2022 May 10. Thorax. 2023. PMID: 35537820 Free PMC article.
RATIONALE: Eosinophils are associated with airway inflammation in respiratory disease. Eosinophil production and survival is controlled partly by interleukin-5: anti-interleukin-5 agents reduce asthma and response correlates with baseline eosinophil counts. H …
RATIONALE: Eosinophils are associated with airway inflammation in respiratory disease. Eosinophil production and survival is c …
Asthma and chronic obstructive pulmonary disease: similarities and differences.
Postma DS, Reddel HK, ten Hacken NH, van den Berge M. Postma DS, et al. Clin Chest Med. 2014 Mar;35(1):143-56. doi: 10.1016/j.ccm.2013.09.010. Epub 2013 Dec 12. Clin Chest Med. 2014. PMID: 24507842 Review.
Asthma and COPD are both heterogeneous lung diseases including many different phenotypes. The classical asthma and COPD phenotypes are easy to discern because they reflect extremes of a phenotypical spectrum. ...
Asthma and COPD are both heterogeneous lung diseases including many different phenotypes. The classical asthma and COPD …
274 results