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Year Number of Results
1986 1
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1995 2
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1998 9
1999 9
2000 7
2001 9
2002 5
2003 5
2004 5
2005 6
2006 5
2007 4
2008 7
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2014 3
2015 5
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Page 1
Sputum cell count: biomarkers in the differentiation of asthma, COPD and asthma-COPD overlap.
Gao J, Zhou W, Chen B, Lin W, Wu S, Wu F. Gao J, et al. Int J Chron Obstruct Pulmon Dis. 2017 Sep 11;12:2703-2710. doi: 10.2147/COPD.S142466. eCollection 2017. Int J Chron Obstruct Pulmon Dis. 2017. PMID: 28979112 Free PMC article.
INTRODUCTION: Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. ...
INTRODUCTION: Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordi …
Effect of aging on sputum inflammation and asthma control.
Busse PJ, Birmingham JM, Calatroni A, Manzi J, Goryachokovsky A, Fontela G, Federman AD, Wisnivesky JP. Busse PJ, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1808-1818.e6. doi: 10.1016/j.jaci.2016.09.015. Epub 2016 Oct 8. J Allergy Clin Immunol. 2017. PMID: 27725186 Free PMC article.
METHODS: We performed a prospective study of aged (>60 years) and younger (21-40 years) inner-city patients with asthma. After a run-in period to control for inhaled corticosteroid use, induced sputum was collected. ...In aged asthmatic patients increased sput …
METHODS: We performed a prospective study of aged (>60 years) and younger (21-40 years) inner-city patients with asthma. After a r …
Automated cell differential count in sputum is feasible and comparable to manual cell count in identifying eosinophilia.
Frøssing L, Hartvig Lindkaer Jensen T, Østrup Nielsen J, Hvidtfeldt M, Silberbrandt A, Parker D, Porsbjerg C, Backer V. Frøssing L, et al. J Asthma. 2022 Mar;59(3):552-560. doi: 10.1080/02770903.2020.1868498. Epub 2021 Jan 8. J Asthma. 2022. PMID: 33356683
INTRODUCTION: Cell differential count (CDC) of induced sputum is considered the gold standard for inflammatory phenotyping of asthma but is not implemented in routine care due to its heavy time- and staff demands. ...The automated cell count …
INTRODUCTION: Cell differential count (CDC) of induced sputum is considered the gold standard for inflammatory phenotyp …
Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma.
Zhi Y, Gao P, Li W, Gao F, Zhang J, Lin H, Zhang J. Zhi Y, et al. Iran J Immunol. 2018 Sep;15(3):239-245. doi: 10.22034/IJI.2018.39393. Iran J Immunol. 2018. PMID: 30246699 Free article.
BACKGROUND: CD163-expressing macrophages are involved in the inflammatory response in asthma. OBJECTIVE: To assess sputum and serum soluble CD163 (sCD163) and cytokine levels in patients with asthma. ...Sputum sCD163 (P=0.020) and serum sCD163 ( …
BACKGROUND: CD163-expressing macrophages are involved in the inflammatory response in asthma. OBJECTIVE: To assess sputum …
Induced sputum in children: success determinants, safety, and cell profiles.
Araújo L, Moreira A, Palmares C, Beltrão M, Fonseca J, Delgado L. Araújo L, et al. J Investig Allergol Clin Immunol. 2011;21(3):216-21. J Investig Allergol Clin Immunol. 2011. PMID: 21548450 Free article.
OBJECTIVES: To evaluate the safety of the procedure and the clinical predictors of successful induction, and to analyze the relationship between sputum cell counts and clinical features in asthmatic and nonasthmatic children. ...We found a positive correlation betwe …
OBJECTIVES: To evaluate the safety of the procedure and the clinical predictors of successful induction, and to analyze the relationship bet …
Sputum induction and its diagnostic applications in inflammatory airway disorders: a review.
Goncalves B, Eze UA. Goncalves B, et al. Front Allergy. 2023 Oct 12;4:1282782. doi: 10.3389/falgy.2023.1282782. eCollection 2023. Front Allergy. 2023. PMID: 37901763 Free PMC article. Review.
However, due to being technically demanding and time-consuming and having the need of employing trained staff, this technique is only used in restricted research centres and in limited centres of clinical use. When the sputum is collected after induction, the primary goal …
However, due to being technically demanding and time-consuming and having the need of employing trained staff, this technique is only used i …
Cell distribution and cytokine levels in induced sputum from healthy subjects and patients with asthma after using different nebulizer techniques.
Koc-Günel S, Schubert R, Zielen S, Rosewich M. Koc-Günel S, et al. BMC Pulm Med. 2018 Jul 13;18(1):115. doi: 10.1186/s12890-018-0683-8. BMC Pulm Med. 2018. PMID: 30005648 Free PMC article.
BACKGROUND: Sputum induction is an important noninvasive method for analyzing bronchial inflammation in patients with asthma and other respiratory diseases. ...The goal of the study was to compare both types of nebulizer devices and their efficacy in inducing spu …
BACKGROUND: Sputum induction is an important noninvasive method for analyzing bronchial inflammation in patients with asthma a …
Autoantibody-mediated Macrophage Dysfunction in Patients with Severe Asthma with Airway Infections.
Son K, Miyasaki K, Salter B, Loukov D, Chon J, Zhao N, Radford K, Huang C, LaVigne N, Dvorkin-Gheva A, Lacy P, Ho T, Bowdish DME, Nair P, Mukherjee M. Son K, et al. Am J Respir Crit Care Med. 2023 Feb 15;207(4):427-437. doi: 10.1164/rccm.202206-1183OC. Am J Respir Crit Care Med. 2023. PMID: 36287613
Multivariate regression analysis confirmed increased frequency of degranulation (free eosinophil granules), increased blood eosinophils (indicative of high T2 burden), increased sputum total cell count, peripheral blood leukocytes (indicative of infection), a …
Multivariate regression analysis confirmed increased frequency of degranulation (free eosinophil granules), increased blood eosinophils (ind …
Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?
Demarche S, Schleich F, Henket M, Paulus V, Van Hees T, Louis R. Demarche S, et al. BMC Pulm Med. 2016 Apr 5;16:46. doi: 10.1186/s12890-016-0208-2. BMC Pulm Med. 2016. PMID: 27044366 Free PMC article.
Asthmatics were classified into inflammatory phenotypes. RESULTS: The total non-squamous cell count per gram of sputum was greater in mixed granulocytic and neutrophilic phenotypes as compared to eosinophilic, paucigranulocytic asthma and healthy subje …
Asthmatics were classified into inflammatory phenotypes. RESULTS: The total non-squamous cell count per gram of sputum …
Involvement and Possible Role of Eosinophils in Asthma Exacerbation.
Nakagome K, Nagata M. Nakagome K, et al. Front Immunol. 2018 Sep 28;9:2220. doi: 10.3389/fimmu.2018.02220. eCollection 2018. Front Immunol. 2018. PMID: 30323811 Free PMC article. Review.
Eosinophils are involved in the development of asthma exacerbation. Recent studies have suggested that sputum and blood eosinophil counts are important factors for predicting asthma exacerbation. In severe eosinophilic asthma, anti-interleukin (IL)-5 m …
Eosinophils are involved in the development of asthma exacerbation. Recent studies have suggested that sputum and blood eosino …
133 results