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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 7
1946 12
1947 50
1948 70
1949 36
1950 65
1951 47
1952 35
1953 59
1954 82
1955 84
1956 71
1957 81
1958 69
1959 66
1960 81
1961 92
1962 100
1963 172
1964 216
1965 153
1966 160
1967 165
1968 167
1969 215
1970 252
1971 273
1972 386
1973 610
1974 447
1975 434
1976 387
1977 340
1978 368
1979 343
1980 307
1981 316
1982 328
1983 327
1984 329
1985 295
1986 286
1987 272
1988 338
1989 332
1990 387
1991 373
1992 356
1993 397
1994 443
1995 402
1996 450
1997 437
1998 424
1999 441
2000 463
2001 509
2002 486
2003 506
2004 516
2005 579
2006 606
2007 684
2008 680
2009 696
2010 716
2011 790
2012 797
2013 871
2014 843
2015 875
2016 807
2017 808
2018 763
2019 799
2020 822
2021 807
2022 862
2023 735
2024 234

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28,675 results

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Page 1
Antitussive therapy: A role for levodropropizine.
Birring S, de Blasio F, Dicpinigaitis PV, Fontana G, Lanata L, Page C, Saibene F, Zanasi A. Birring S, et al. Pulm Pharmacol Ther. 2019 Jun;56:79-85. doi: 10.1016/j.pupt.2019.03.003. Epub 2019 Mar 11. Pulm Pharmacol Ther. 2019. PMID: 30872161 Review.
The poor tolerability of most available antitussives is closely related to their action on the central nervous system (CNS). An international group of experts specialized in cough met to discuss the need to identify an effective antitussive treatment with a good tol …
The poor tolerability of most available antitussives is closely related to their action on the central nervous system (CNS). An inter …
Antitussive drugs--past, present, and future.
Dicpinigaitis PV, Morice AH, Birring SS, McGarvey L, Smith JA, Canning BJ, Page CP. Dicpinigaitis PV, et al. Pharmacol Rev. 2014 Mar 26;66(2):468-512. doi: 10.1124/pr.111.005116. Print 2014. Pharmacol Rev. 2014. PMID: 24671376 Review.
This article reviews our current understanding of the pathogenesis of cough and the hypertussive state characterizing a number of diseases as well as reviewing the evidence for the different classes of antitussive drug currently in clinical use. For completeness, the revie …
This article reviews our current understanding of the pathogenesis of cough and the hypertussive state characterizing a number of diseases a …
Novel antitussive strategies.
Morjaria JB, Dickinson RS, Morice AH. Morjaria JB, et al. Drug Discov Today. 2013 Apr;18(7-8):380-8. doi: 10.1016/j.drudis.2012.11.004. Epub 2012 Nov 16. Drug Discov Today. 2013. PMID: 23159360 Review.
Numerous initiatives targeting the recently discovered tussive pathways are in progress. Here, we review the current antitussive armamentarium and provide an update on the novel strategies and compounds in development....
Numerous initiatives targeting the recently discovered tussive pathways are in progress. Here, we review the current antitussive arma …
The nonnarcotic antitussive drug dimemorfan: a review.
Ida H. Ida H. Clin Ther. 1997 Mar-Apr;19(2):215-31. doi: 10.1016/s0149-2918(97)80111-7. Clin Ther. 1997. PMID: 9152562 Review.
The antitussive dimemorfan phosphate was discovered through extensive screening of morphinic derivatives and was introduced in Japan in 1975. ...Dimemorfan is therefore considered a nonnarcotic antitussive. Studies of antitussive effects in animal models indi …
The antitussive dimemorfan phosphate was discovered through extensive screening of morphinic derivatives and was introduced in Japan …
Antitussive activity of alcoxyphenyl carbamic acid analogues.
Jurecekova J, Nosalova G, Jurecek L, Csollei J, Sivova V, Nosal S. Jurecekova J, et al. Gen Physiol Biophys. 2018 May;37(3):337-343. doi: 10.4149/gpb_2017048. Gen Physiol Biophys. 2018. PMID: 29938679
In this study we report pharmacological evaluation of four newly synthetized analogues of alcoxyphenyl carbamic acid, structurally related to butamirate citrate that is frequently used as cough suppressing drug, and marked as ATK 231, ATK 241, ATK 251 and ATK 261. These agents …
In this study we report pharmacological evaluation of four newly synthetized analogues of alcoxyphenyl carbamic acid, structurally related t …
Antitussive agents.
Brunk SF. Brunk SF. J Iowa Med Soc. 1973 Feb;63(2):53 passim. J Iowa Med Soc. 1973. PMID: 4687454 No abstract available.
Antitussive and expectorant activities of licorice and its major compounds.
Kuang Y, Li B, Fan J, Qiao X, Ye M. Kuang Y, et al. Bioorg Med Chem. 2018 Jan 1;26(1):278-284. doi: 10.1016/j.bmc.2017.11.046. Epub 2017 Dec 2. Bioorg Med Chem. 2018. PMID: 29224994
Licorice has been used as an antitussive and expectorant herbal medicine for a long history. This work evaluated the activities of 14 major compounds and crude extracts of licorice, using the classical ammonia-induced cough model and phenol red secretion model in mice. ... …
Licorice has been used as an antitussive and expectorant herbal medicine for a long history. This work evaluated the activities of 14 …
Xingbei antitussive granules ameliorate cough hypersensitivity in post-infectious cough guinea pigs by regulating tryptase/PAR2/TRPV1 pathway.
Li Y, Zhao R, Zhang M, Shen K, Hou X, Liu B, Li C, Sun B, Xiang M, Lin J. Li Y, et al. J Ethnopharmacol. 2024 Jan 30;319(Pt 3):117243. doi: 10.1016/j.jep.2023.117243. Epub 2023 Sep 28. J Ethnopharmacol. 2024. PMID: 37777025
ETHNOPHARMACOLOGICAL RELEVANCE: Xingbei antitussive granules (XB) is a classic Chinese Medicine prescription for treating post-infectious cough(PIC), based on the Sanao Decoction from Formularies of the Bureau of People's Welfare Pharmacies in the Song Dynasty and Jiegeng …
ETHNOPHARMACOLOGICAL RELEVANCE: Xingbei antitussive granules (XB) is a classic Chinese Medicine prescription for treating post-infect …
Peripheral mechanisms II: the pharmacology of peripherally active antitussive drugs.
Spina D, McFadzean I, Bertram FK, Page CP. Spina D, et al. Handb Exp Pharmacol. 2009;187(187):155-86. doi: 10.1007/978-3-540-79842-2_8. Handb Exp Pharmacol. 2009. PMID: 18825340 Free PMC article. Review.
Cough remains a major unmet medical need and although the centrally acting opioids have remained the antitussive of choice for decades, they have many unwanted side effects. However, new research into the behaviour of airway sensory nerves has provided greater insight into …
Cough remains a major unmet medical need and although the centrally acting opioids have remained the antitussive of choice for decade …
28,675 results
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