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Detrimental effects of 2-arachidonoylglycerol on whole blood platelet aggregation and on cerebral blood flow after a focal ischemic insult in rats.
Shearer JA, Coker SJ, Carswell HVO. Shearer JA, et al. Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H967-H977. doi: 10.1152/ajpheart.00299.2017. Epub 2018 Jan 5. Am J Physiol Heart Circ Physiol. 2018. PMID: 29351454 Free article.
2-Arachidonoylglycerol (2-AG) is a major modulator of blood flow and platelet aggregation and a potential neuroprotectant. The present study investigated, for the first time, the effects of 2-AG on cerebral blood flow (CBF) in the first critical …
2-Arachidonoylglycerol (2-AG) is a major modulator of blood flow and platelet aggregation and a potential neuroprotecta …
Role of CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation.
Díaz-García E, García-Tovar S, Alfaro E, Zamarrón E, Mangas A, Galera R, Ruíz-Hernández JJ, Solé-Violán J, Rodríguez-Gallego C, Van-Den-Rym A, Pérez-de-Diego R, Nanwani-Nanwani K, López-Collazo E, García-Rio F, Cubillos-Zapata C. Díaz-García E, et al. Front Immunol. 2022 Jan 31;13:847894. doi: 10.3389/fimmu.2022.847894. eCollection 2022. Front Immunol. 2022. PMID: 35173744 Free PMC article.
COVID-19 patients showed extracellular accumulation of adenosine nucleotides (ATP and ADP), resulting in systemic inflammation and pro-coagulant state, as a consequence of purinergic pathway dysregulation. Interestingly, we found that COVID-19 plasma caused platelet activa …
COVID-19 patients showed extracellular accumulation of adenosine nucleotides (ATP and ADP), resulting in systemic inflammation and pro-coagu …
Pivotal role of platelets in critical illness: evidence behind clinical interventions.
Collins AS. Collins AS. Dimens Crit Care Nurs. 2004 Sep-Oct;23(5):217-21. doi: 10.1097/00003465-200409000-00006. Dimens Crit Care Nurs. 2004. PMID: 15722844 Review.
Platelet cell processes are powerful modulators of immunology, thrombosis, fibrinolysis, and angiogenic responses. Platelet active drugs intervene in platelet activation, adhesion, aggregation, and secretion. ...
Platelet cell processes are powerful modulators of immunology, thrombosis, fibrinolysis, and angiogenic responses. Platelet …