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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1963 1
1964 4
1965 3
1967 7
1968 8
1969 8
1970 5
1971 9
1972 7
1973 13
1974 22
1975 41
1976 44
1977 35
1978 51
1979 51
1980 62
1981 59
1982 47
1983 65
1984 88
1985 95
1986 101
1987 131
1988 115
1989 133
1990 158
1991 157
1992 181
1993 182
1994 192
1995 169
1996 158
1997 173
1998 183
1999 217
2000 251
2001 222
2002 277
2003 258
2004 316
2005 339
2006 346
2007 389
2008 404
2009 412
2010 401
2011 418
2012 426
2013 474
2014 452
2015 448
2016 431
2017 444
2018 457
2019 452
2020 439
2021 308
2022 199
2023 194
2024 50

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10,731 results

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Page 1
Epilepsy in adults.
Thijs RD, Surges R, O'Brien TJ, Sander JW. Thijs RD, et al. Lancet. 2019 Feb 16;393(10172):689-701. doi: 10.1016/S0140-6736(18)32596-0. Epub 2019 Jan 24. Lancet. 2019. PMID: 30686584 Review.
These advances have resulted in the new classification of epileptic seizures and epilepsies. A detailed clinical history and a reliable eyewitness account of a seizure are the cornerstones of the diagnosis. ...Epilepsy surgery is the most effective way …
These advances have resulted in the new classification of epileptic seizures and epilepsies. A detailed clinical history and a …
Epilepsy.
Devinsky O, Vezzani A, O'Brien TJ, Jette N, Scheffer IE, de Curtis M, Perucca P. Devinsky O, et al. Nat Rev Dis Primers. 2018 May 3;4:18024. doi: 10.1038/nrdp.2018.24. Nat Rev Dis Primers. 2018. PMID: 29722352 Review.
The accurate diagnosis of seizures is essential as some patients will be misdiagnosed with epilepsy, whereas others will receive an incorrect diagnosis. ...In addition, one-third of patients will continue to have uncontrolled seizures. Epilepsy can sub …
The accurate diagnosis of seizures is essential as some patients will be misdiagnosed with epilepsy, whereas others will recei …
Epilepsy: Is there hope?
Guerreiro CA. Guerreiro CA. Indian J Med Res. 2016 Nov;144(5):657-660. doi: 10.4103/ijmr.IJMR_1051_16. Indian J Med Res. 2016. PMID: 28361817 Free PMC article. Review.
Refractory epilepsies occur in approximately one-third of recently diagnosed patients with epilepsy. ...There is evidence of improvement in the understanding of epilepsy and a clear progress in the management of epileptic seizures in recent times....
Refractory epilepsies occur in approximately one-third of recently diagnosed patients with epilepsy. ...There is evidence of i …
Dravet syndrome.
Lagae L. Lagae L. Curr Opin Neurol. 2021 Apr 1;34(2):213-218. doi: 10.1097/WCO.0000000000000902. Curr Opin Neurol. 2021. PMID: 33395108 Review.
Therefore, the efficacy of the new treatment options, which now become available, should not only focus on seizure frequency reduction but also on the long-term effects on these comorbidities, such as intellectual disability, motor and sleep problems. ...Genetic treatments …
Therefore, the efficacy of the new treatment options, which now become available, should not only focus on seizure frequency reductio …
Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders.
Devinsky O, Cilio MR, Cross H, Fernandez-Ruiz J, French J, Hill C, Katz R, Di Marzo V, Jutras-Aswad D, Notcutt WG, Martinez-Orgado J, Robson PJ, Rohrback BG, Thiele E, Whalley B, Friedman D. Devinsky O, et al. Epilepsia. 2014 Jun;55(6):791-802. doi: 10.1111/epi.12631. Epub 2014 May 22. Epilepsia. 2014. PMID: 24854329 Free PMC article. Review.
To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regard to its relevance to epilepsy and other selected neuropsychiatric disorders. We summarize the presentations from a conference in which invited participants reviewed rele …
To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regard to its relevance to epilepsy
Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis.
Lattanzi S, Brigo F, Trinka E, Zaccara G, Cagnetti C, Del Giovane C, Silvestrini M. Lattanzi S, et al. Drugs. 2018 Nov;78(17):1791-1804. doi: 10.1007/s40265-018-0992-5. Drugs. 2018. PMID: 30390221
BACKGROUND: Approximately one-third of patients with epilepsy presents seizures despite adequate treatment. Hence, there is the need to search for new therapeutic options. ...CONCLUSIONS: Adjunctive CBD in patients with LGS or DS experiencing seizures uncontr …
BACKGROUND: Approximately one-third of patients with epilepsy presents seizures despite adequate treatment. Hence, there is th …
Cannabis for the Treatment of Epilepsy: an Update.
Gaston TE, Szaflarski JP. Gaston TE, et al. Curr Neurol Neurosci Rep. 2018 Sep 8;18(11):73. doi: 10.1007/s11910-018-0882-y. Curr Neurol Neurosci Rep. 2018. PMID: 30194563 Review.
We also discuss the most recent studies on various artisanal CBD products conducted in patients with epilepsy in the USA and internationally. While a high percentage of patients in these studies reported improvement in seizures, these studies were either retrospecti …
We also discuss the most recent studies on various artisanal CBD products conducted in patients with epilepsy in the USA and internat …
Effects of psychotropic drugs on seizure threshold.
Pisani F, Oteri G, Costa C, Di Raimondo G, Di Perri R. Pisani F, et al. Drug Saf. 2002;25(2):91-110. doi: 10.2165/00002018-200225020-00004. Drug Saf. 2002. PMID: 11888352 Review.
Apart from drug-related factors, seizure precipitation during psychotropic drug medication is greatly influenced by the individual's inherited seizure threshold and, particularly, by the presence of seizurogenic conditions (such as history of epilepsy, brain …
Apart from drug-related factors, seizure precipitation during psychotropic drug medication is greatly influenced by the individual's …
Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial.
Kotulska K, Kwiatkowski DJ, Curatolo P, Weschke B, Riney K, Jansen F, Feucht M, Krsek P, Nabbout R, Jansen AC, Wojdan K, Sijko K, Głowacka-Walas J, Borkowska J, Sadowski K, Domańska-Pakieła D, Moavero R, Hertzberg C, Hulshof H, Scholl T, Benova B, Aronica E, de Ridder J, Lagae L, Jóźwiak S; EPISTOP Investigators. Kotulska K, et al. Ann Neurol. 2021 Feb;89(2):304-314. doi: 10.1002/ana.25956. Epub 2020 Nov 27. Ann Neurol. 2021. PMID: 33180985 Free PMC article. Clinical Trial.
Subjects were followed until 2 years of age. The primary endpoint was the time to first clinical seizure. RESULTS: In 54 subjects, epileptiform EEG abnormalities were identified before seizures. ...INTERPRETATION: Preventive treatment with vigabatrin was safe and mo …
Subjects were followed until 2 years of age. The primary endpoint was the time to first clinical seizure. RESULTS: In 54 subjects, ep …
Perampanel as precision therapy in rare genetic epilepsies.
Nissenkorn A, Kluger G, Schubert-Bast S, Bayat A, Bobylova M, Bonanni P, Ceulemans B, Coppola A, Di Bonaventura C, Feucht M, Fuchs A, Gröppel G, Heimer G, Herdt B, Kulikova S, Mukhin K, Nicassio S, Orsini A, Panagiotou M, Pringsheim M, Puest B, Pylaeva O, Ramantani G, Tsekoura M, Ricciardelli P, Lerman Sagie T, Stark B, Striano P, van Baalen A, De Wachter M, Cerulli Irelli E, Cuccurullo C, von Stülpnagel C, Russo A. Nissenkorn A, et al. Epilepsia. 2023 Apr;64(4):866-874. doi: 10.1111/epi.17530. Epub 2023 Feb 20. Epilepsia. 2023. PMID: 36734057
Retrospective data from patients with genetic epilepsies treated with perampanel were collected. Outcome measures were responder rate (50% seizure reduction), and percentage of seizure reduction after 3 months of treatment. ...Eleven of 17 (64.7%) patients wi …
Retrospective data from patients with genetic epilepsies treated with perampanel were collected. Outcome measures were responder rate …
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