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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2006 1
2007 3
2008 2
2009 1
2010 2
2013 1
2014 1
2016 2
2017 2
2024 0

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14 results

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Page 1
[Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease].
Shim YK, Kim N. Shim YK, et al. Korean J Gastroenterol. 2016 Jun 25;67(6):300-12. doi: 10.4166/kjg.2016.67.6.300. Korean J Gastroenterol. 2016. PMID: 27312830 Free article. Review. Korean.
Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation. In addition, low dose aspirin is employed as an anti-coagulant for those …
Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due t …
Aspirin dosing for the prevention and treatment of ischemic stroke: an indication-specific review of the literature.
Ansara AJ, Nisly SA, Arif SA, Koehler JM, Nordmeyer ST. Ansara AJ, et al. Ann Pharmacother. 2010 May;44(5):851-62. doi: 10.1345/aph.1M346. Epub 2010 Apr 13. Ann Pharmacother. 2010. PMID: 20388864 Free article. Review.
OBJECTIVE: To evaluate the efficacy of aspirin for the treatment and prevention of ischemic stroke and identify the minimum dose proven to be effective for each indication. ...Aspirin has been proven to prevent ischemic stroke in a variety of settings. …
OBJECTIVE: To evaluate the efficacy of aspirin for the treatment and prevention of ischemic stroke and identify the minimum do …
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
Lemaitre RN, Rice K, Marciante K, Bis JC, Lumley TS, Wiggins KL, Smith NL, Heckbert SR, Psaty BM. Lemaitre RN, et al. Atherosclerosis. 2009 Jun;204(2):e58-63. doi: 10.1016/j.atherosclerosis.2008.10.011. Epub 2008 Nov 1. Atherosclerosis. 2009. PMID: 19046748 Free PMC article.
We investigated the association of common genetic variation in prostaglandin H synthase 1 (PTGS1), prostaglandin H synthase 2 (PTGS2), thromboxane A2 synthase (TBXAS1), prostacyclin synthase (PTGIS), prostaglandin E synthase …
We investigated the association of common genetic variation in prostaglandin H synthase 1 (PTGS1), prostaglandin H s …
Risk of cardiovascular events associated with selective COX-2 inhibitors.
Mukherjee D, Nissen SE, Topol EJ. Mukherjee D, et al. JAMA. 2001 Aug 22-29;286(8):954-9. doi: 10.1001/jama.286.8.954. JAMA. 2001. PMID: 11509060 Review.
Our search yielded 2 major randomized trials, the Vioxx Gastrointestinal Outcomes Research Study (VIGOR; 8076 patients) and the Celecoxib Long-term Arthritis Safety Study (CLASS; 8059 patients), as well as 2 smaller trials with approximately 1000 patients each. The results from V …
Our search yielded 2 major randomized trials, the Vioxx Gastrointestinal Outcomes Research Study (VIGOR; 8076 patients) and the Celecoxib Lo …
Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study.
Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. Lee CR, et al. Clin Pharmacol Ther. 2008 Jan;83(1):52-60. doi: 10.1038/sj.clpt.6100221. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495879 Free PMC article.
Cyclooxygenase-derived prostaglandins modulate cardiovascular disease risk. We genotyped 2212 Atherosclerosis Risk in Communities study participants (1,023 incident coronary heart disease (CHD) cases; 270 incident ischemic stroke cases; 919 non- …
Cyclooxygenase-derived prostaglandins modulate cardiovascular disease risk. We genotyped 2212 Atherosclerosis Risk in Communit …
Polymorphisms of prostaglandin-endoperoxide synthase 2 gene, and prostaglandin-E receptor 2 gene, C-reactive protein concentrations and risk of atherothrombosis: a nested case-control approach.
Hegener HH, Diehl KA, Kurth T, Gaziano JM, Ridker PM, Zee RY. Hegener HH, et al. J Thromb Haemost. 2006 Aug;4(8):1718-22. doi: 10.1111/j.1538-7836.2006.02054.x. J Thromb Haemost. 2006. PMID: 16879213 Free article. Clinical Trial.
OBJECTIVE: Recent data have shown an association between polymorphisms of prostaglandin-endoperoxide synthase-2 gene (PTGS2; alias COX-2), and prostaglandin-E receptor-2 gene (PTGER2) and risk of atherothrombotic disorders. ...In contrast to pri …
OBJECTIVE: Recent data have shown an association between polymorphisms of prostaglandin-endoperoxide synthase-2 gene (P …
Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients.
Yi X, Wang C, Zhou Q, Lin J. Yi X, et al. BMC Neurol. 2017 Jan 9;17(1):4. doi: 10.1186/s12883-016-0788-8. BMC Neurol. 2017. PMID: 28068952 Free PMC article.
We sought to assess the association of genetic variants with AR and early clinical outcomes in patients with acute ischemic stroke (IS). METHODS: A total of 850 acute IS patients were consecutively enrolled. ...The primary outcome was early neurological deterioratio …
We sought to assess the association of genetic variants with AR and early clinical outcomes in patients with acute ischemic stroke …
Impacts of COX-1 gene polymorphisms on vascular outcomes in patients with ischemic stroke and treated with aspirin.
Cao L, Zhang Z, Sun W, Bai W, Sun W, Zhang Y, Wang X, Cai B, Xie X, Duan Z, Cai Q, Liu D, Xiong Y, Ma M, Liu X, Xu G. Cao L, et al. Gene. 2014 Aug 10;546(2):172-6. doi: 10.1016/j.gene.2014.06.023. Epub 2014 Jun 12. Gene. 2014. PMID: 24930730 Clinical Trial.
The primary endpoint was a composite of nonfatal ischemic stroke, myocardial infarction, and death from cardiovascular causes. ...The impacts of other three tested polymorphisms on primary endpoint were unremarkable. In conclusion, in Chinese patients with ischem …
The primary endpoint was a composite of nonfatal ischemic stroke, myocardial infarction, and death from cardiovascular causes. …
Association between PTGS1 polymorphisms and functional outcomes in Chinese patients with stroke during aspirin therapy: Interaction with smoking.
Cai H, Cai B, Sun L, Zhang H, Zhou S, Cao L, Guo H, Sun W, Yan B, Davis SM, Zhang Z, Liu X. Cai H, et al. J Neurol Sci. 2017 May 15;376:211-215. doi: 10.1016/j.jns.2017.03.014. Epub 2017 Mar 14. J Neurol Sci. 2017. PMID: 28431615
PURPOSE: Prostaglandin-Endoperoxide Synthase 1 (PTGS1) and smoking may play important roles in aspirin nonresponsiveness, but the effect of their interaction on stroke outcomes remains largely unknown. We examined the effects of PTGS1 polymorphisms, sm …
PURPOSE: Prostaglandin-Endoperoxide Synthase 1 (PTGS1) and smoking may play important roles in aspirin nonresponsivenes …
Interaction between COX-1 and COX-2 Variants Associated with Aspirin Resistance in Chinese Stroke Patients.
Yi X, Cheng W, Lin J, Zhou Q, Wang C. Yi X, et al. J Stroke Cerebrovasc Dis. 2016 Sep;25(9):2136-44. doi: 10.1016/j.jstrokecerebrovasdis.2016.05.039. Epub 2016 Jun 16. J Stroke Cerebrovasc Dis. 2016. PMID: 27318652
The aim of this study was to investigate the association of the COX genetic variants and interaction among these variants with AR in patients with acute ischemic stroke (IS). METHODS: We consecutively enrolled 850 acute IS patients. ...The combinational analysis use …
The aim of this study was to investigate the association of the COX genetic variants and interaction among these variants with AR in patient …
14 results