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Angiogenin and tRNA fragments in Parkinson's disease and neurodegeneration.
Prehn JHM, Jirström E. Prehn JHM, et al. Acta Pharmacol Sin. 2020 Apr;41(4):442-446. doi: 10.1038/s41401-020-0375-9. Epub 2020 Mar 6. Acta Pharmacol Sin. 2020. PMID: 32144338 Free PMC article. Review.
In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative disorders, with a specific focus on Parkinson's disease (PD). ...Delivery of angiogenin protein reduces neurod …
In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative di …
Angiogenin variants are not associated with Parkinson's disease in the ethnic Chinese population.
Liu B, Zhang Y, Wang Y, Xiao Q, Yang Q, Wang G, Ma J, Zhao J, Quinn TJ, Chen SD, Liu J. Liu B, et al. Parkinsonism Relat Disord. 2013 Apr;19(4):446-7. doi: 10.1016/j.parkreldis.2012.11.016. Epub 2012 Dec 8. Parkinsonism Relat Disord. 2013. PMID: 23231972
But there have been no studies investigating the association between angiogenin and Parkinson's disease in the ethnic Chinese population. We conducted a case-control study to evaluate the association between angiogenin and Parkinson's …
But there have been no studies investigating the association between angiogenin and Parkinson's disease in the e …
Assessment of ANG variants in Parkinson's disease.
Grenn FP, Moore A, Bandres-Ciga S, Krohn L, Blauwendraat C; International Parkinson's Disease Genomics Consortium (IPDGC). Grenn FP, et al. Neurobiol Aging. 2021 Aug;104:111.e1-111.e4. doi: 10.1016/j.neurobiolaging.2021.03.006. Epub 2021 Mar 24. Neurobiol Aging. 2021. PMID: 33875291 Free PMC article.
Genetic risk factors are occasionally shared between different neurodegenerative diseases. Previous studies have linked ANG, a gene encoding angiogenin, to both Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS). ...We further explored th …
Genetic risk factors are occasionally shared between different neurodegenerative diseases. Previous studies have linked ANG, a gene encoding …
A neuroprotective role for angiogenin in models of Parkinson's disease.
Steidinger TU, Standaert DG, Yacoubian TA. Steidinger TU, et al. J Neurochem. 2011 Feb;116(3):334-41. doi: 10.1111/j.1471-4159.2010.07112.x. Epub 2010 Dec 22. J Neurochem. 2011. PMID: 21091473 Free PMC article.
We previously observed marked down-regulation of the mRNA for angiogenin, a potent inducer of neovascularization, in a mouse model of Parkinson's disease (PD) based on over-expression of alpha-synuclein. ...In this study, we confirmed that mouse ang …
We previously observed marked down-regulation of the mRNA for angiogenin, a potent inducer of neovascularization, in a mouse model of …
Mutational analysis of angiogenin gene in Parkinson's disease.
Chen ML, Wu RM, Tai CH, Lin CH. Chen ML, et al. PLoS One. 2014 Nov 11;9(11):e112661. doi: 10.1371/journal.pone.0112661. eCollection 2014. PLoS One. 2014. PMID: 25386690 Free PMC article.
Parkinsonism has been noted in kindreds with ANG mutations and variants in the ANG gene have been found to associate with PD in two Caucasian populations. We therefore hypothesized that mutations in ANG may also contribute to idiopathic Parkinson's disease …
Parkinsonism has been noted in kindreds with ANG mutations and variants in the ANG gene have been found to associate with PD in two C …
Vitamin D and Parkinson's disease.
Vinh Quôc Luong K, Thi Hoàng Nguyên L. Vinh Quôc Luong K, et al. J Neurosci Res. 2012 Dec;90(12):2227-36. doi: 10.1002/jnr.23115. Epub 2012 Aug 28. J Neurosci Res. 2012. PMID: 22930493 Review.
Parkinson's disease (PD) is the second most common form of neurodegeneration among the elderly population. ...Genetic studies have provided the opportunity to determine which proteins link vitamin D to PD pathology, e.g., Nurr1 gene, toll-like receptor, gene …
Parkinson's disease (PD) is the second most common form of neurodegeneration among the elderly population. ...Genetic s …
Serum angiogenin levels are elevated in ALS, but not Parkinson's disease.
van Es MA, Veldink JH, Schelhaas HJ, Bloem BR, Sodaar P, van Nuenen BF, Verbeek M, van de Warrenburg BP, van den Berg LH. van Es MA, et al. J Neurol Neurosurg Psychiatry. 2014 Dec;85(12):1439-40. doi: 10.1136/jnnp-2013-307168. Epub 2014 May 29. J Neurol Neurosurg Psychiatry. 2014. PMID: 24876190 No abstract available.
Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Bradshaw WJ, Rehman S, Pham TT, Thiyagarajan N, Lee RL, Subramanian V, Acharya KR. Bradshaw WJ, et al. Sci Rep. 2017 Feb 8;7:41996. doi: 10.1038/srep41996. Sci Rep. 2017. PMID: 28176817 Free PMC article.
Mutations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are known to be associated with Amyotrophic Lateral Sclerosis (ALS, motor neurone disease) (sporadic and familial) and Parkinson's Disease (PD). .. …
Mutations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are known to be associated with Amy …
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis.
van Es MA, Schelhaas HJ, van Vught PW, Ticozzi N, Andersen PM, Groen EJ, Schulte C, Blauw HM, Koppers M, Diekstra FP, Fumoto K, LeClerc AL, Keagle P, Bloem BR, Scheffer H, van Nuenen BF, van Blitterswijk M, van Rheenen W, Wills AM, Lowe PP, Hu GF, Yu W, Kishikawa H, Wu D, Folkerth RD, Mariani C, Goldwurm S, Pezzoli G, Van Damme P, Lemmens R, Dahlberg C, Birve A, Fernández-Santiago R, Waibel S, Klein C, Weber M, van der Kooi AJ, de Visser M, Verbaan D, van Hilten JJ, Heutink P, Hennekam EA, Cuppen E, Berg D, Brown RH Jr, Silani V, Gasser T, Ludolph AC, Robberecht W, Ophoff RA, Veldink JH, Pasterkamp RJ, de Bakker PI, Landers JE, van de Warrenburg BP, van den Berg LH. van Es MA, et al. Ann Neurol. 2011 Dec;70(6):964-73. doi: 10.1002/ana.22611. Ann Neurol. 2011. PMID: 22190368 Free PMC article. Review.
OBJECTIVE: Several studies have suggested an increased frequency of variants in the gene encoding angiogenin (ANG) in patients with amyotrophic lateral sclerosis (ALS). Interestingly, a few ALS patients carrying ANG variants also showed signs of Parkinson disease …
OBJECTIVE: Several studies have suggested an increased frequency of variants in the gene encoding angiogenin (ANG) in patients with a …
Angiogenin in Parkinson disease models: role of Akt phosphorylation and evaluation of AAV-mediated angiogenin expression in MPTP treated mice.
Steidinger TU, Slone SR, Ding H, Standaert DG, Yacoubian TA. Steidinger TU, et al. PLoS One. 2013;8(2):e56092. doi: 10.1371/journal.pone.0056092. Epub 2013 Feb 7. PLoS One. 2013. PMID: 23409128 Free PMC article.
The angiogenic factor, angiogenin, has been recently linked to both Amyotrophic Lateral Sclerosis (ALS) and Parkinson Disease (PD). ...Furthermore, an ALS-associated mutant of angiogenin, K40I, which fails to induce Akt phosphorylation, was similar to …
The angiogenic factor, angiogenin, has been recently linked to both Amyotrophic Lateral Sclerosis (ALS) and Parkinson Disea …
21 results