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1983 1
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Page 1
Continuous noninvasive respiratory volume monitoring for the identification of patients at risk for opioid-induced respiratory depression and obstructive breathing patterns.
Voscopoulos CJ, MacNabb CM, Freeman J, Galvagno SM Jr, Ladd D, George E. Voscopoulos CJ, et al. J Trauma Acute Care Surg. 2014 Sep;77(3 Suppl 2):S208-15. doi: 10.1097/TA.0000000000000400. J Trauma Acute Care Surg. 2014. PMID: 25159358 Clinical Trial.
BACKGROUND: Opioid-induced respiratory depression (OIRD) and postoperative apnea (POA) can lead to complications after surgery or traumatic injury. Previously, real-time monitoring of respiratory insufficiency and identification of apneic …
BACKGROUND: Opioid-induced respiratory depression (OIRD) and postoperative apnea (POA) can lead to complications …
Increased tidal volume variability in children is a better marker of opioid-induced respiratory depression than decreased respiratory rate.
Barbour SJ, Vandebeek CA, Ansermino JM. Barbour SJ, et al. J Clin Monit Comput. 2004 Jun;18(3):171-8. doi: 10.1023/b:jocm.0000042922.63647.b9. J Clin Monit Comput. 2004. PMID: 15562983
OBJECTIVE: During opioid administration, decreasing respiratory rate is typically used as a predictor of respiratory depression. ...We hypothesize that opioid administration to children will increase tidal volume variability (TV(var)) and …
OBJECTIVE: During opioid administration, decreasing respiratory rate is typically used as a predictor of respiratory
Evidence for the emergence of an opioid-resistant respiratory rhythm following fentanyl overdose.
Haouzi P, Mellen N, McCann M, Sternick M, Guck D, Tubbs N. Haouzi P, et al. Respir Physiol Neurobiol. 2020 Jun;277:103428. doi: 10.1016/j.resp.2020.103428. Epub 2020 Mar 6. Respir Physiol Neurobiol. 2020. PMID: 32151709
Breathing resumes within one to two minutes following fentanyl overdose induced apnea in spontaneously breathing rats. As this regular rhythm is produced at a time wherein fentanyl concentrations and receptor occupancy are likely to be extremely high, the mechanisms initia …
Breathing resumes within one to two minutes following fentanyl overdose induced apnea in spontaneously breathing rats. As this regula …
Effects of Opioids Given to Facilitate Mechanical Ventilation on Sleep Apnea After Extubation in the Intensive Care Unit.
Timm FP, Zaremba S, Grabitz SD, Farhan HN, Zaremba S, Siliski E, Shin CH, Muse S, Friedrich S, Mojica JE, Kurth T, Ramachandran SK, Eikermann M. Timm FP, et al. Sleep. 2018 Jan 1;41(1). doi: 10.1093/sleep/zsx191. Sleep. 2018. PMID: 29182729
STUDY OBJECTIVES: Following extubation in the intensive care unit (ICU), upper airway (UA) edema and respiratory depressants may promote UA dysfunction. We tested the hypothesis that opioids increase the risk of sleep apnea early after extubation. ...RESULTS: Sleep …
STUDY OBJECTIVES: Following extubation in the intensive care unit (ICU), upper airway (UA) edema and respiratory depressants may prom …
Respiratory inductive plethysmography as a method for measuring ventilatory parameters in conscious, non-restrained dogs.
Murphy DJ, Renninger JP, Schramek D. Murphy DJ, et al. J Pharmacol Toxicol Methods. 2010 Jul-Aug;62(1):47-53. doi: 10.1016/j.vascn.2010.04.006. Epub 2010 May 8. J Pharmacol Toxicol Methods. 2010. PMID: 20435149
RESULTS: Measurement of ventilatory parameters in dogs following manual placement in different positions (e.g., standing, sitting, lateral recumbent) or during the different postures in non-restrained dogs demonstrated that changes in posture had only a minimal influence (
RESULTS: Measurement of ventilatory parameters in dogs following manual placement in different positions (e.g., standing, sitting, lateral r …
A risk stratification algorithm using non-invasive respiratory volume monitoring to improve safety when using post-operative opioids in the PACU.
Voscopoulos C, Theos K, Tillmann Hein HA, George E. Voscopoulos C, et al. J Clin Monit Comput. 2017 Apr;31(2):417-426. doi: 10.1007/s10877-016-9841-9. Epub 2016 Feb 19. J Clin Monit Comput. 2017. PMID: 26894592
Late detection of respiratory depression in non-intubated patients compromises patient safety. ...A decline in minute ventilation (MV) is the earliest sign of respiratory depression. A non-invasive respiratory volume monitor (RVM) that pr …
Late detection of respiratory depression in non-intubated patients compromises patient safety. ...A decline in minute ventilat …
Recurrent hypoxia in rats during development increases subsequent respiratory sensitivity to fentanyl.
Moss IR, Brown KA, Laferrière A. Moss IR, et al. Anesthesiology. 2006 Oct;105(4):715-8. doi: 10.1097/00000542-200610000-00017. Anesthesiology. 2006. PMID: 17006070 Free article.
BACKGROUND: In children with a history of significant obstructive sleep apnea who undergo adenotonsillectomy, postsurgical administration of opiates has been alleged to be associated with an increased risk for respiratory complications, including respiratory
BACKGROUND: In children with a history of significant obstructive sleep apnea who undergo adenotonsillectomy, postsurgical administra …
Hypoxic ventilatory response in Tac1-/- neonatal mice following exposure to opioids.
Berner J, Shvarev Y, Zimmer A, Wickstrom R. Berner J, et al. J Appl Physiol (1985). 2012 Dec 1;113(11):1718-26. doi: 10.1152/japplphysiol.00188.2012. Epub 2012 Oct 11. J Appl Physiol (1985). 2012. PMID: 23065762 Free article.
Morphine is the dominating analgetic drug used in neonates, but opioid-induced respiratory depression limits its therapeutic use. ...These data suggest that opioids and the substance P-ergic system interact in the HVR, and that reducing the activity in the ta …
Morphine is the dominating analgetic drug used in neonates, but opioid-induced respiratory depression limits its therap …
Postoperative respiratory arrhythmias: incidence and measurement.
Sleigh JW. Sleigh JW. Acta Anaesthesiol Scand. 1999 Aug;43(7):708-14. doi: 10.1034/j.1399-6576.1999.430704.x. Acta Anaesthesiol Scand. 1999. PMID: 10456809
BACKGROUND: Postoperative respiratory disturbances may be the result either of depression of respiratory drive, or alteration of respiratory pattern. ...The ventilatory response to hypercapnia was measured preoperatively, and at the start and end of th …
BACKGROUND: Postoperative respiratory disturbances may be the result either of depression of respiratory drive, or alte …
Ventilatory response to morphine in young and old subjects.
Arunasalam K, Davenport HT, Painter S, Jones JG. Arunasalam K, et al. Anaesthesia. 1983 Jun;38(6):529-33. Anaesthesia. 1983. PMID: 6408943 Free article.
However, in the older group seven out of thirteen subjects showed frequent periods of apnoea or periodic breathing whereas three of the young subjects had these phenomena at much less frequent intervals. Respiratory depression after morphine is similar in old …
However, in the older group seven out of thirteen subjects showed frequent periods of apnoea or periodic breathing whereas three of t …