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1988 2
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1,735 results

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Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair.
Zaiss DMW, Gause WC, Osborne LC, Artis D. Zaiss DMW, et al. Immunity. 2015 Feb 17;42(2):216-226. doi: 10.1016/j.immuni.2015.01.020. Immunity. 2015. PMID: 25692699 Free PMC article. Review.
Emerging data suggest that in addition to characteristic type 2-associated cytokines, the epidermal growth factor (EGF)-like molecule Amphiregulin (AREG) might be a critical component of type 2-mediated resistance and tolerance. ...
Emerging data suggest that in addition to characteristic type 2-associated cytokines, the epidermal growth factor (EGF)-like molecule Amp …
Amphiregulin.
Berasain C, Avila MA. Berasain C, et al. Semin Cell Dev Biol. 2014 Apr;28:31-41. doi: 10.1016/j.semcdb.2014.01.005. Epub 2014 Jan 23. Semin Cell Dev Biol. 2014. PMID: 24463227 Review.
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. ...
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. ...
Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing.
du Halgouet A, Darbois A, Alkobtawi M, Mestdagh M, Alphonse A, Premel V, Yvorra T, Colombeau L, Rodriguez R, Zaiss D, El Morr Y, Bugaut H, Legoux F, Perrin L, Aractingi S, Golub R, Lantz O, Salou M. du Halgouet A, et al. Immunity. 2023 Jan 10;56(1):78-92.e6. doi: 10.1016/j.immuni.2022.12.004. Immunity. 2023. PMID: 36630919 Free PMC article.
Using skin grafts, parabiosis, and adoptive transfer experiments, we show that MAIT cells migrated into the wound in a T cell receptor (TCR)-independent but CXCR6 chemokine receptor-dependent manner. Amphiregulin secreted by MAIT cells following excision promoted wound hea …
Using skin grafts, parabiosis, and adoptive transfer experiments, we show that MAIT cells migrated into the wound in a T cell receptor (TCR) …
Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts.
Zhao X, Yang W, Yu T, Yu Y, Cui X, Zhou Z, Yang H, Yu Y, Bilotta AJ, Yao S, Xu J, Zhou J, Yochum GS, Koltun WA, Portolese A, Zeng D, Xie J, Pinchuk IV, Zhang H, Cong Y. Zhao X, et al. Gastroenterology. 2023 Jan;164(1):89-102. doi: 10.1053/j.gastro.2022.09.006. Epub 2022 Sep 13. Gastroenterology. 2023. PMID: 36113570 Free PMC article.
A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels RM, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM. Minutti CM, et al. Immunity. 2019 Mar 19;50(3):645-654.e6. doi: 10.1016/j.immuni.2019.01.008. Epub 2019 Feb 12. Immunity. 2019. PMID: 30770250 Free PMC article.
The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the restoration of tissue homeostasis after injury; however, the mechanism by which Amphiregulin contributes to wound repair remains unknown. Here we show that Amphiregulin …
The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the restoration of tissue homeostasis after in …
Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells.
Kaiser KA, Loffredo LF, Santos-Alexis KL, Ringham OR, Arpaia N. Kaiser KA, et al. J Exp Med. 2023 Mar 6;220(3):e20221462. doi: 10.1084/jem.20221462. Epub 2022 Dec 19. J Exp Med. 2023. PMID: 36534084 Free PMC article.
Lung regulatory T (Treg) cells are critical for maintaining blood oxygenation following influenza virus infection through production of the EGFR ligand amphiregulin (Areg); however, how Treg cells engage with progenitors within the alveolar niche is unknown. ...
Lung regulatory T (Treg) cells are critical for maintaining blood oxygenation following influenza virus infection through production of the …
Amphiregulin couples IL1RL1(+) regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity.
Sun R, Zhao H, Gao DS, Ni A, Li H, Chen L, Lu X, Chen K, Lu B. Sun R, et al. Sci Adv. 2023 Aug 25;9(34):eadd7399. doi: 10.1126/sciadv.add7399. Epub 2023 Aug 23. Sci Adv. 2023. PMID: 37611111 Free PMC article.
Whole tumor single-cell RNA sequencing (scRNA-seq) analysis and blockade experiments revealed that the amphiregulin (AREG)-epidermal growth factor receptor (EGFR) axis mediated cross-talk between IL1RL1(+) T(reg) cells and CAFs. ...
Whole tumor single-cell RNA sequencing (scRNA-seq) analysis and blockade experiments revealed that the amphiregulin (AREG)-epidermal …
Amphiregulin in lung diseases: A review.
Shen C, Fan X, Mao Y, Jiang J. Shen C, et al. Medicine (Baltimore). 2024 Feb 23;103(8):e37292. doi: 10.1097/MD.0000000000037292. Medicine (Baltimore). 2024. PMID: 38394508 Free PMC article. Review.
Studies have found that amphiregulin plays an important role in the occurrence and development of lung diseases. This paper mainly reviews the structure and function of amphiregulin and focuses on the important role of amphiregulin in lung diseases....
Studies have found that amphiregulin plays an important role in the occurrence and development of lung diseases. This paper mainly re …
Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis.
Savage TM, Fortson KT, de Los Santos-Alexis K, Oliveras-Alsina A, Rouanne M, Rae SS, Gamarra JR, Shayya H, Kornberg A, Cavero R, Li F, Han A, Haeusler RA, Adam J, Schwabe RF, Arpaia N. Savage TM, et al. Immunity. 2024 Feb 13;57(2):303-318.e6. doi: 10.1016/j.immuni.2024.01.009. Epub 2024 Feb 2. Immunity. 2024. PMID: 38309273
Production of amphiregulin (Areg) by regulatory T (Treg) cells promotes repair after acute tissue injury. ...
Production of amphiregulin (Areg) by regulatory T (Treg) cells promotes repair after acute tissue injury. ...
The role of amphiregulin in ovarian function and disease.
Fang L, Sun YP, Cheng JC. Fang L, et al. Cell Mol Life Sci. 2023 Feb 7;80(3):60. doi: 10.1007/s00018-023-04709-8. Cell Mol Life Sci. 2023. PMID: 36749397 Review.
Amphiregulin (AREG) is an epidermal growth factor (EGF)-like growth factor that binds exclusively to the EGF receptor (EGFR). ...
Amphiregulin (AREG) is an epidermal growth factor (EGF)-like growth factor that binds exclusively to the EGF receptor (EGFR). ...
1,735 results

Searches related to "amphiregulin"