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Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Di Chiara G, Imperato A. Di Chiara G, et al. Proc Natl Acad Sci U S A. 1988 Jul;85(14):5274-8. doi: 10.1073/pnas.85.14.5274. Proc Natl Acad Sci U S A. 1988. PMID: 2899326 Free PMC article.
Haloperidol, a neuroleptic drug, increased extracellular dopamine concentrations, but this effect was not preferential for the accumbens and was associated with hypomotility and sedation. Drugs not abused by humans [e.g., imipramine (an antidepressant), atropine (an …
Haloperidol, a neuroleptic drug, increased extracellular dopamine concentrations, but this effect was not preferential for the …
Evidence for a noradrenergic mechanism in the grooming produced by (+)-amphetamine and 4, alpha-dimethyl-m-tyramine (H 77/77) in rats.
Lassen JB. Lassen JB. Psychopharmacology (Berl). 1977 Oct 20;54(2):153-7. doi: 10.1007/BF00426772. Psychopharmacology (Berl). 1977. PMID: 144928
One hour after the light was switched on, physiological saline, (+)-amphetamine 1 mg/kg, and H 77/77 5 mg/kg were injected s.c.; the number of groomings was counted 1-2 h after the treatments. (+)-Amphetamine and H 77/77 produced increased grooming which was antagon …
One hour after the light was switched on, physiological saline, (+)-amphetamine 1 mg/kg, and H 77/77 5 mg/kg were injected s.c.; the …
Drug-induced parkinsonism following chronic methamphetamine use by a patient on haloperidol decanoate.
Matthew BJ, Gedzior JS. Matthew BJ, et al. Int J Psychiatry Med. 2015;50(4):405-11. doi: 10.1177/0091217415612736. Epub 2015 Nov 2. Int J Psychiatry Med. 2015. PMID: 26526398
The report also illustrates the neuronal workings due to chronic methamphetamine-use and the additive effects of dopamine blockade by antipsychotics such as haloperidol....
The report also illustrates the neuronal workings due to chronic methamphetamine-use and the additive effects of dopamine blockade by …