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Did you mean ambrosini (1,742 results)?
Perindopril/Ambrosin Combination Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice: Crosstalk between Toll-Like Receptor 4, the Pro-Inflammatory Pathways, and SIRT1/PPAR-gamma Signaling.
Kabel AM, Atef A, Borg HM, El-Sheikh AAK, Al Khabbaz HJ, Arab HH, Estfanous RS. Kabel AM, et al. Pharmaceuticals (Basel). 2022 May 13;15(5):600. doi: 10.3390/ph15050600. Pharmaceuticals (Basel). 2022. PMID: 35631426 Free PMC article.
In addition, each ambrosin or perindopril alone or in combination inhibits apoptosis and augments the mediators of autophagy in DSS-treated mice. ...In conclusion, the perindopril/ambrosin combination might represent an effective modality for mitigation of the patho …
In addition, each ambrosin or perindopril alone or in combination inhibits apoptosis and augments the mediators of autophagy in DSS-t …
Ambrosin sesquiterpene lactone exerts selective and potent anticancer effects in drug-resistant human breast cancer cells (MDA-MB-231) through mitochondrial mediated apoptosis, ROS generation and targeting Akt/beta-Catenin signaling pathway.
Fan S, Cui Y, Hu Z, Wang W, Jiang W, Xu H. Fan S, et al. J BUON. 2020 Sep-Oct;25(5):2221-2227. J BUON. 2020. PMID: 33277839 Free article.
The cytotoxicity of ambrosin was also investigated on the MCF-12A normal breast cells which showed that it exerted very low toxic effects on these cells. Ambrosin also caused remarkable changes in the morphology and suppressed the colony forming potential of MDA-MB- …
The cytotoxicity of ambrosin was also investigated on the MCF-12A normal breast cells which showed that it exerted very low toxic eff …
Ambrosin, a potent NF-kappabeta inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin.
Khalil MNA, Choucry MA, El Senousy AS, Hassan A, El-Marasy SA, El Awdan SA, Omar FA. Khalil MNA, et al. PLoS One. 2019 Jul 5;14(7):e0219378. doi: 10.1371/journal.pone.0219378. eCollection 2019. PLoS One. 2019. PMID: 31276550 Free PMC article.
In contrast, ambrsoin, a sesquiterpene lactone which is a potent NF-kappabeta inhibitor, is scarcely studied in AD models. The current work aims to assess the efficacy of ambrosin as a possible remedy for AD. In silico studies showed that bioavailability and BBB permeabili …
In contrast, ambrsoin, a sesquiterpene lactone which is a potent NF-kappabeta inhibitor, is scarcely studied in AD models. The current work …
Synthesis and cytotoxicity of water-soluble ambrosin prodrug candidates.
Hejchman E, Haugwitz RD, Cushman M. Hejchman E, et al. J Med Chem. 1995 Aug 18;38(17):3407-10. doi: 10.1021/jm00017a025. J Med Chem. 1995. PMID: 7650694
The potential therapeutic application of the naturally occurring, cytotoxic pseudoguaianolide sesquiterpene lactone ambrosin is limited by its aqueous insolubility. A number of water-soluble ambrosin derivatives have therefore been prepared for potential use as prod …
The potential therapeutic application of the naturally occurring, cytotoxic pseudoguaianolide sesquiterpene lactone ambrosin is limit …
Trypanocidal and toxicological assessment in vitro and in silico of three sesquiterpene lactones from Asteraceae plant species.
Sepúlveda-Robles O, Espinoza-Gutiérrez B, Gomez-Verjan JC, Guzmán-Gutiérrez SL, De Ita M, Silva-Miranda M, Espitia-Pinzón CI, Fernández-Ramírez F, Herrera-Salazar A, Mata-Rocha M, Ortega-Hernández A, Reyes-Chilpa R. Sepúlveda-Robles O, et al. Food Chem Toxicol. 2019 Mar;125:55-61. doi: 10.1016/j.fct.2018.12.023. Epub 2018 Dec 18. Food Chem Toxicol. 2019. PMID: 30572063
We report the effect of the Sesquiterpene Lactones Ambrosin, Incomptine B and Glaucolide E against seven strains of Trypanosoma cruzi, the etiological agent of Chagas Disease. ...We evaluated by flow cytometry the viability of epimastigotes. Ambrosin was the most ef …
We report the effect of the Sesquiterpene Lactones Ambrosin, Incomptine B and Glaucolide E against seven strains of Trypanosoma cruzi …
Anti-cancer stem cell activity of a sesquiterpene lactone isolated from Ambrosia arborescens and of a synthetic derivative.
Sotillo WS, Villagomez R, Smiljanic S, Huang X, Malakpour A, Kempengren S, Rodrigo G, Almanza G, Sterner O, Oredsson S. Sotillo WS, et al. PLoS One. 2017 Sep 1;12(9):e0184304. doi: 10.1371/journal.pone.0184304. eCollection 2017. PLoS One. 2017. PMID: 28863191 Free PMC article.
All compounds inhibited cell proliferation; however, damsin and ambrosin were toxic at single-digit micromolar ranges, while higher concentrations were required for coronopilin and dindol-01. ...Treatment with damsin and ambrosin decreased the CSC subpopulation and …
All compounds inhibited cell proliferation; however, damsin and ambrosin were toxic at single-digit micromolar ranges, while higher c …
Cell cycle regulation by p38 MAP kinases.
Ambrosino C, Nebreda AR. Ambrosino C, et al. Biol Cell. 2001 Sep;93(1-2):47-51. doi: 10.1016/s0248-4900(01)01124-8. Biol Cell. 2001. PMID: 11730321 Review. No abstract available.
Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.
Saeed ME, Abdelgadir H, Sugimoto Y, Khalid HE, Efferth T. Saeed ME, et al. J Ethnopharmacol. 2015 Nov 4;174:644-58. doi: 10.1016/j.jep.2015.07.005. Epub 2015 Jul 10. J Ethnopharmacol. 2015. PMID: 26165828
Microarray-based mRNA expression profiling, COMPARE, and hierarchical cluster analyses were applied to identify, which genes correlate with sensitivity or resistance to ambrosin, the main constituent of the most active extract Ambrosia maritima. RESULTS: The results of the …
Microarray-based mRNA expression profiling, COMPARE, and hierarchical cluster analyses were applied to identify, which genes correlate with …
28 results