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Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy.

Afzal MZ, Reiter M, Gastonguay C, McGivern JV, Guan X, Ge ZD, Mack DL, Childers MK, Ebert AD, Strande JL.

J Cardiovasc Pharmacol Ther. 2016 Mar 2. pii: 1074248416636477. [Epub ahead of print]


Impact of a cytomegalovirus kinase inhibitor on infection and neuronal progenitor cell differentiation.

Bigley TM, McGivern JV, Ebert AD, Terhune SS.

Antiviral Res. 2016 May;129:67-73. doi: 10.1016/j.antiviral.2016.02.007. Epub 2016 Feb 11.


Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation.

Schwab AJ, Ebert AD.

Stem Cell Reports. 2015 Dec 8;5(6):1039-52. doi: 10.1016/j.stemcr.2015.11.004.


SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons.

Patitucci TN, Ebert AD.

Hum Mol Genet. 2016 Feb 1;25(3):514-23. doi: 10.1093/hmg/ddv489. Epub 2015 Dec 7.


Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R.

Stem Cell Reports. 2015 Dec 8;5(6):933-45. doi: 10.1016/j.stemcr.2015.10.011. Epub 2015 Nov 21.


Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease.

Rivero-Ríos P, Gómez-Suaga P, Fernández B, Madero-Pérez J, Schwab AJ, Ebert AD, Hilfiker S.

Biochem Soc Trans. 2015 Jun;43(3):390-5. doi: 10.1042/BST20140301.


Astrocytes influence the severity of spinal muscular atrophy.

Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL.

Hum Mol Genet. 2015 Jul 15;24(14):4094-102. doi: 10.1093/hmg/ddv148. Epub 2015 Apr 24.


Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results.

Yu H, Fischer G, Ebert AD, Wu HE, Bai X, Hogan QH.

Mol Pain. 2015 Feb 12;11:5. doi: 10.1186/s12990-015-0002-9.


Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice.

Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ.

BMC Genet. 2014 Dec 5;15:135. doi: 10.1186/s12863-014-0135-2.


Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy.

Schwab AJ, Ebert AD.

PLoS One. 2014 Jul 23;9(7):e103112. doi: 10.1371/journal.pone.0103112. eCollection 2014.


Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture.

Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M.

Stem Cells Transl Med. 2014 May;3(5):564-74. doi: 10.5966/sctm.2013-0143. Epub 2014 Mar 21.


Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments.

McGivern JV, Ebert AD.

Adv Drug Deliv Rev. 2014 Apr;69-70:170-8. doi: 10.1016/j.addr.2013.11.012. Epub 2013 Dec 2. Review.


Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.

Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ.

Am J Hum Genet. 2013 Dec 5;93(6):1001-14. doi: 10.1016/j.ajhg.2013.10.011. Epub 2013 Nov 14.


Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production.

McGivern JV, Patitucci TN, Nord JA, Barabas ME, Stucky CL, Ebert AD.

Glia. 2013 Sep;61(9):1418-28. doi: 10.1002/glia.22522. Epub 2013 Jul 10.


EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.

Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN.

Stem Cell Res. 2013 May;10(3):417-27. doi: 10.1016/j.scr.2013.01.009. Epub 2013 Feb 4.


COPI transport complexes bind to specific RNAs in neuronal cells.

Todd AG, Lin H, Ebert AD, Liu Y, Androphy EJ.

Hum Mol Genet. 2013 Feb 15;22(4):729-36. doi: 10.1093/hmg/dds480. Epub 2012 Nov 21.


The future of neurodegenerative diseases: emerging targets, treatments and technologies.

Voss J, Ebert A, Wolfe M, Lindsley C, Cookson M, Deane R.

Future Med Chem. 2012 Sep;4(13):1661-9. doi: 10.4155/fmc.12.118. No abstract available.


Modeling neurodegenerative diseases using stem cells: is it accelerating drug discovery?

Ebert AD.

Future Med Chem. 2012 Sep;4(13):1651-3. doi: 10.4155/fmc.12.101. No abstract available.


Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.

HD iPSC Consortium.

Cell Stem Cell. 2012 Aug 3;11(2):264-78. doi: 10.1016/j.stem.2012.04.027. Epub 2012 Jun 28.


Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.

Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN.

PLoS One. 2012;7(6):e39113. doi: 10.1371/journal.pone.0039113. Epub 2012 Jun 19.

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