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Results: 1 to 20 of 27

1.

Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy.

Schwab AJ, Ebert AD.

PLoS One. 2014 Jul 23;9(7):e103112. doi: 10.1371/journal.pone.0103112. eCollection 2014.

PMID:
25054590
[PubMed - in process]
Free Article
2.

Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture.

Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M.

Stem Cells Transl Med. 2014 May;3(5):564-74. doi: 10.5966/sctm.2013-0143. Epub 2014 Mar 21.

PMID:
24657962
[PubMed - indexed for MEDLINE]
3.

Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments.

McGivern JV, Ebert AD.

Adv Drug Deliv Rev. 2014 Apr;69-70:170-8. doi: 10.1016/j.addr.2013.11.012. Epub 2013 Dec 2.

PMID:
24309014
[PubMed - in process]
4.

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.

Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ.

Am J Hum Genet. 2013 Dec 5;93(6):1001-14. doi: 10.1016/j.ajhg.2013.10.011. Epub 2013 Nov 14.

PMID:
24239381
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production.

McGivern JV, Patitucci TN, Nord JA, Barabas ME, Stucky CL, Ebert AD.

Glia. 2013 Sep;61(9):1418-28. doi: 10.1002/glia.22522. Epub 2013 Jul 10.

PMID:
23839956
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.

Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN.

Stem Cell Res. 2013 May;10(3):417-27. doi: 10.1016/j.scr.2013.01.009. Epub 2013 Feb 4.

PMID:
23474892
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

COPI transport complexes bind to specific RNAs in neuronal cells.

Todd AG, Lin H, Ebert AD, Liu Y, Androphy EJ.

Hum Mol Genet. 2013 Feb 15;22(4):729-36. doi: 10.1093/hmg/dds480. Epub 2012 Nov 21.

PMID:
23175440
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The future of neurodegenerative diseases: emerging targets, treatments and technologies.

Voss J, Ebert A, Wolfe M, Lindsley C, Cookson M, Deane R.

Future Med Chem. 2012 Sep;4(13):1661-9. doi: 10.4155/fmc.12.118. No abstract available.

PMID:
22924504
[PubMed - indexed for MEDLINE]
9.

Modeling neurodegenerative diseases using stem cells: is it accelerating drug discovery?

Ebert AD.

Future Med Chem. 2012 Sep;4(13):1651-3. doi: 10.4155/fmc.12.101. No abstract available.

PMID:
22924501
[PubMed - indexed for MEDLINE]
Free Article
10.

Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.

HD iPSC Consortium.

Cell Stem Cell. 2012 Aug 3;11(2):264-78. doi: 10.1016/j.stem.2012.04.027. Epub 2012 Jun 28.

PMID:
22748968
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.

Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN.

PLoS One. 2012;7(6):e39113. doi: 10.1371/journal.pone.0039113. Epub 2012 Jun 19.

PMID:
22723941
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.

Jodelka FM, Ebert AD, Duelli DM, Hastings ML.

Hum Mol Genet. 2010 Dec 15;19(24):4906-17. doi: 10.1093/hmg/ddq425. Epub 2010 Sep 30.

PMID:
20884664
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Stem cell model of spinal muscular atrophy.

Ebert AD, Svendsen CN.

Arch Neurol. 2010 Jun;67(6):665-9. doi: 10.1001/archneurol.2010.89. Review.

PMID:
20558385
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Human stem cells and drug screening: opportunities and challenges.

Ebert AD, Svendsen CN.

Nat Rev Drug Discov. 2010 May;9(5):367-72. doi: 10.1038/nrd3000. Epub 2010 Mar 26.

PMID:
20339370
[PubMed - indexed for MEDLINE]
15.

Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease.

Ebert AD, Barber AE, Heins BM, Svendsen CN.

Exp Neurol. 2010 Jul;224(1):155-62. doi: 10.1016/j.expneurol.2010.03.005. Epub 2010 Mar 19.

PMID:
20227407
[PubMed - indexed for MEDLINE]
16.

Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.

Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN.

PLoS One. 2009 Oct 29;4(10):e7630. doi: 10.1371/journal.pone.0007630.

PMID:
19898616
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model.

Mattis VB, Ebert AD, Fosso MY, Chang CW, Lorson CL.

Hum Mol Genet. 2009 Oct 15;18(20):3906-13. doi: 10.1093/hmg/ddp333. Epub 2009 Jul 21.

PMID:
19625298
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Induced pluripotent stem cells from a spinal muscular atrophy patient.

Ebert AD, Yu J, Rose FF Jr, Mattis VB, Lorson CL, Thomson JA, Svendsen CN.

Nature. 2009 Jan 15;457(7227):277-80. doi: 10.1038/nature07677. Epub 2008 Dec 21.

PMID:
19098894
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF.

Behrstock S, Ebert AD, Klein S, Schmitt M, Moore JM, Svendsen CN.

Cell Transplant. 2008;17(7):753-62.

PMID:
19044202
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Isolating, expanding, and infecting human and rodent fetal neural progenitor cells.

Ebert AD, McMillan EL, Svendsen CN.

Curr Protoc Stem Cell Biol. 2008 Sep;Chapter 2:Unit 2D.2. doi: 10.1002/9780470151808.sc02d02s6.

PMID:
18819085
[PubMed - indexed for MEDLINE]

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