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Results: 1 to 20 of 31


Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease.

Rivero-Ríos P, Gómez-Suaga P, Fernández B, Madero-Pérez J, Schwab AJ, Ebert AD, Hilfiker S.

Biochem Soc Trans. 2015 Jun;43(3):390-5. doi: 10.1042/BST20140301.


Astrocytes influence the severity of spinal muscular atrophy.

Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL.

Hum Mol Genet. 2015 Jul 15;24(14):4094-102. doi: 10.1093/hmg/ddv148. Epub 2015 Apr 24.


Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results.

Yu H, Fischer G, Ebert AD, Wu HE, Bai X, Hogan QH.

Mol Pain. 2015 Feb 12;11:5. doi: 10.1186/s12990-015-0002-9.


Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice.

Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ.

BMC Genet. 2014 Dec 5;15:135. doi: 10.1186/s12863-014-0135-2.


Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy.

Schwab AJ, Ebert AD.

PLoS One. 2014 Jul 23;9(7):e103112. doi: 10.1371/journal.pone.0103112. eCollection 2014.


Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture.

Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M.

Stem Cells Transl Med. 2014 May;3(5):564-74. doi: 10.5966/sctm.2013-0143. Epub 2014 Mar 21.


Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments.

McGivern JV, Ebert AD.

Adv Drug Deliv Rev. 2014 Apr;69-70:170-8. doi: 10.1016/j.addr.2013.11.012. Epub 2013 Dec 2. Review.


Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.

Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ.

Am J Hum Genet. 2013 Dec 5;93(6):1001-14. doi: 10.1016/j.ajhg.2013.10.011. Epub 2013 Nov 14.


Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production.

McGivern JV, Patitucci TN, Nord JA, Barabas ME, Stucky CL, Ebert AD.

Glia. 2013 Sep;61(9):1418-28. doi: 10.1002/glia.22522. Epub 2013 Jul 10.


EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.

Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN.

Stem Cell Res. 2013 May;10(3):417-27. doi: 10.1016/j.scr.2013.01.009. Epub 2013 Feb 4.


COPI transport complexes bind to specific RNAs in neuronal cells.

Todd AG, Lin H, Ebert AD, Liu Y, Androphy EJ.

Hum Mol Genet. 2013 Feb 15;22(4):729-36. doi: 10.1093/hmg/dds480. Epub 2012 Nov 21.


The future of neurodegenerative diseases: emerging targets, treatments and technologies.

Voss J, Ebert A, Wolfe M, Lindsley C, Cookson M, Deane R.

Future Med Chem. 2012 Sep;4(13):1661-9. doi: 10.4155/fmc.12.118. No abstract available.


Modeling neurodegenerative diseases using stem cells: is it accelerating drug discovery?

Ebert AD.

Future Med Chem. 2012 Sep;4(13):1651-3. doi: 10.4155/fmc.12.101. No abstract available.


Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.

HD iPSC Consortium.

Cell Stem Cell. 2012 Aug 3;11(2):264-78. doi: 10.1016/j.stem.2012.04.027. Epub 2012 Jun 28.


Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.

Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN.

PLoS One. 2012;7(6):e39113. doi: 10.1371/journal.pone.0039113. Epub 2012 Jun 19.


A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.

Jodelka FM, Ebert AD, Duelli DM, Hastings ML.

Hum Mol Genet. 2010 Dec 15;19(24):4906-17. doi: 10.1093/hmg/ddq425. Epub 2010 Sep 30.


Stem cell model of spinal muscular atrophy.

Ebert AD, Svendsen CN.

Arch Neurol. 2010 Jun;67(6):665-9. doi: 10.1001/archneurol.2010.89. Review.


Human stem cells and drug screening: opportunities and challenges.

Ebert AD, Svendsen CN.

Nat Rev Drug Discov. 2010 May;9(5):367-72. doi: 10.1038/nrd3000. Epub 2010 Mar 26.


Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease.

Ebert AD, Barber AE, Heins BM, Svendsen CN.

Exp Neurol. 2010 Jul;224(1):155-62. doi: 10.1016/j.expneurol.2010.03.005. Epub 2010 Mar 19.


Chromosome 7 and 19 trisomy in cultured human neural progenitor cells.

Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN.

PLoS One. 2009 Oct 29;4(10):e7630. doi: 10.1371/journal.pone.0007630.

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