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Page 1
The pharmacokinetics of flavanones.
Najmanová I, Vopršalová M, Saso L, Mladěnka P. Najmanová I, et al. Crit Rev Food Sci Nutr. 2020;60(18):3155-3171. doi: 10.1080/10408398.2019.1679085. Epub 2019 Oct 25. Crit Rev Food Sci Nutr. 2020. PMID: 31650849 Review.
The major reason for this is that although flavanones are absorbed into enterocytes after oral intake, they are rapidly metabolized, in particular, into conjugates, sulfates and glucuronides, which are the major forms circulating in plasma. (2) A large fraction reaches the colon …
The major reason for this is that although flavanones are absorbed into enterocytes after oral intake, they are rapidly metabolized, in part …
Naturally occurring triterpenoid saponins.
Dinda B, Debnath S, Mohanta BC, Harigaya Y. Dinda B, et al. Chem Biodivers. 2010 Oct;7(10):2327-580. doi: 10.1002/cbdv.200800070. Chem Biodivers. 2010. PMID: 20963775 Review.
New saponins are arranged in Table 1 on the basis of the skeletal structures of their aglycones, e.g., oleanane type, ursane type, lupane type, hopane type, taraxastane type, cycloartane type, lanostane type, tirucallane type, dammarane type, cucurbitane type, and h …
New saponins are arranged in Table 1 on the basis of the skeletal structures of their aglycones, e.g., oleanane type, ursane t …
Non-holostane aglycones of sea cucumber triterpene glycosides. Structure, biosynthesis, evolution.
Kalinin VI, Silchenko AS, Avilov SA, Stonik VA. Kalinin VI, et al. Steroids. 2019 Jul;147:42-51. doi: 10.1016/j.steroids.2018.11.010. Epub 2018 Nov 22. Steroids. 2019. PMID: 30468785 Review.
Triterpene glycosides are known as characteristic metabolites of sea cucumbers (class Holothuroidea, phylum Echinodermata). The most of them have lanostane aglycones containing 18(20)-lactone, i.e. belongs to so-called holostane series. ...Probably, these natural pr …
Triterpene glycosides are known as characteristic metabolites of sea cucumbers (class Holothuroidea, phylum Echinodermata). The most of them …
Human UDP-glucuronosyltransferase 2B7.
Radominska-Pandya A, Little JM, Czernik PJ. Radominska-Pandya A, et al. Curr Drug Metab. 2001 Sep;2(3):283-98. doi: 10.2174/1389200013338379. Curr Drug Metab. 2001. PMID: 11513331
UDP-Glucuronosyltransferases (UGTs) are glycoproteins, localized in endoplasmic reticulum (ER) and nuclear membranes, which catalyze the confugation of a broad variety of lipophilic aglycon substrates with glucuronic acid using UDP-glucuronic acid (UDP-GlcUA) as the sugar …
UDP-Glucuronosyltransferases (UGTs) are glycoproteins, localized in endoplasmic reticulum (ER) and nuclear membranes, which catalyze the con …
Studies on Natural Products Using Monoclonal Antibodies: A Review.
Shoyama Y. Shoyama Y. Antibodies (Basel). 2021 Nov 1;10(4):43. doi: 10.3390/antib10040043. Antibodies (Basel). 2021. PMID: 34842627 Free PMC article. Review.
Antigen components were divided into two categories based on their function, i.e., their membrane recognizing (aglycone part) and fixing (sugar moiety) abilities. ...
Antigen components were divided into two categories based on their function, i.e., their membrane recognizing (aglycone part) …
Synthesis of Type-I and Type-II LacNAc-Repeating Oligosaccharides as the Backbones of Tumor-Associated Lewis Antigens.
Phang R, Lin CH. Phang R, et al. Front Immunol. 2022 Feb 23;13:858894. doi: 10.3389/fimmu.2022.858894. eCollection 2022. Front Immunol. 2022. PMID: 35281035 Free PMC article. Review.
Additionally, we also highlight solutions that have been offered to tackle long-lasting problems, e.g., prevention of the oxazoline formation and change of donor/acceptor reactivity. ...
Additionally, we also highlight solutions that have been offered to tackle long-lasting problems, e.g., prevention of the oxazoline f …
Glycosyltransferases, important tools for drug design.
Luzhetskyy A, Méndez C, Salas JA, Bechthold A. Luzhetskyy A, et al. Curr Top Med Chem. 2008;8(8):680-709. doi: 10.2174/156802608784221514. Curr Top Med Chem. 2008. PMID: 18473892 Review.
Usually the biosynthetic pathways to deoxysugars start from a monosacchride-1-phosphate which is converted to a NDP-hexose by a nucleotidyltransferase. Modification of this intermediate by different enzymes (e.g. dehydratases, epimerases, aminotransferases) yields the fina …
Usually the biosynthetic pathways to deoxysugars start from a monosacchride-1-phosphate which is converted to a NDP-hexose by a nucleotidylt …
Anodic Reactivity of Alkyl S-Glucosides.
Deore B, Ocando JE, Pham LD, Sanhueza CA. Deore B, et al. J Org Chem. 2022 May 6;87(9):5952-5960. doi: 10.1021/acs.joc.2c00222. Epub 2022 Apr 13. J Org Chem. 2022. PMID: 35417151
The oxidation potential of alkyl S-glucosides, estimated herein from square-wave voltammetry peak potentials (E(p)), depends on the steric properties of the aglycone. Glucosides substituted with bulky groups exhibit E(p) values at voltages more positive than …
The oxidation potential of alkyl S-glucosides, estimated herein from square-wave voltammetry peak potentials (E(p)), depends on the s …
Analysis of flavonoids in foods and biological samples.
Gonzalez-Paramas AM, Santos-Buelga C, Duenas M, Gonzalez-Manzano S. Gonzalez-Paramas AM, et al. Mini Rev Med Chem. 2011 Dec;11(14):1239-55. doi: 10.2174/13895575111091239. Mini Rev Med Chem. 2011. PMID: 22070683 Review.
Flavonoids are a major class of plant phenolics that are widely distributed in the human diet and have been related to health promotion. They may occur in their natural sources in free forms (aglycones), as glycosylated or acylated derivatives, or as oligomeric and polymer …
Flavonoids are a major class of plant phenolics that are widely distributed in the human diet and have been related to health promotion. The …
Potential Therapeutic Effects of Oleuropein Aglycone in Alzheimer's Disease.
Martorell M, Forman K, Castro N, Capó X, Tejada S, Sureda A. Martorell M, et al. Curr Pharm Biotechnol. 2016;17(11):994-1001. doi: 10.2174/1389201017666160725120656. Curr Pharm Biotechnol. 2016. PMID: 27455905 Review.
In the current work, available literature on oleuropein aglycone effects as antioxidant and inhibitor of amyloid deposits in AD is reviewed. Moreover, we discuss the chemistry, food sources and bioavailability of oleuropein aglycone....
In the current work, available literature on oleuropein aglycone effects as antioxidant and inhibitor of amyloid deposits in AD is re …
1,329 results