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Results: 1 to 20 of 211

1.

A Conserved Transcriptional Signature of Delayed Aging and Reduced Disease Vulnerability Is Partially Mediated by SIRT3.

Barger JL, Anderson RM, Newton MA, da Silva C, Vann JA, Pugh TD, Someya S, Prolla TA, Weindruch R.

PLoS One. 2015 Apr 1;10(4):e0120738. doi: 10.1371/journal.pone.0120738. eCollection 2015.

3.

Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations.

Wierman MB, Matecic M, Valsakumar V, Li M, Smith DL Jr, Bekiranov S, Smith JS.

Aging (Albany NY). 2015 Mar;7(3):177-94.

4.

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

Youm YH, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti TD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, Alnemri E, Dixit VD.

Nat Med. 2015 Mar;21(3):263-9. doi: 10.1038/nm.3804. Epub 2015 Feb 16.

PMID:
25686106
5.

Epigenetic linkage of aging, cancer and nutrition.

Daniel M, Tollefsbol TO.

J Exp Biol. 2015 Jan 1;218(Pt 1):59-70. doi: 10.1242/jeb.107110.

PMID:
25568452
6.

Regulation of energy balance by inflammation: common theme in physiology and pathology.

Wang H, Ye J.

Rev Endocr Metab Disord. 2015 Mar;16(1):47-54. doi: 10.1007/s11154-014-9306-8.

PMID:
25526866
7.

Sirtuin modulators: an updated patent review (2012 - 2014).

Mellini P, Valente S, Mai A.

Expert Opin Ther Pat. 2015 Jan;25(1):5-15. doi: 10.1517/13543776.2014.982532. Epub 2014 Nov 29.

PMID:
25435179
8.

Impact of nutrition on the ageing process.

Mathers JC.

Br J Nutr. 2015 Jan;113 Suppl:S18-22. doi: 10.1017/S0007114514003237. Epub 2014 Nov 21.

PMID:
25415221
9.

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.

Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ.

J Exp Med. 2014 Nov 17;211(12):2373-83. doi: 10.1084/jem.20140116. Epub 2014 Nov 3.

PMID:
25366964
10.

How Much Should We Weigh for a Long and Healthy Life Span? The Need to Reconcile Caloric Restriction versus Longevity with Body Mass Index versus Mortality Data.

Lorenzini A.

Front Endocrinol (Lausanne). 2014 Jul 30;5:121. doi: 10.3389/fendo.2014.00121. eCollection 2014. Review.

11.

Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.

Lees EK, Król E, Grant L, Shearer K, Wyse C, Moncur E, Bykowska AS, Mody N, Gettys TW, Delibegovic M.

Aging Cell. 2014 Oct;13(5):817-27. doi: 10.1111/acel.12238. Epub 2014 Jun 17.

12.

Glutamatergic signaling and low prodynorphin expression are associated with intact memory and reduced anxiety in rat models of healthy aging.

Ménard C, Quirion R, Bouchard S, Ferland G, Gaudreau P.

Front Aging Neurosci. 2014 May 7;6:81. doi: 10.3389/fnagi.2014.00081. eCollection 2014.

13.

Bariatric surgery and diet-induced long-term caloric restriction protect subcutaneous adipose-derived stromal/progenitor cells and prolong their life span in formerly obese humans.

Mitterberger MC, Mattesich M, Zwerschke W.

Exp Gerontol. 2014 Aug;56:106-13. doi: 10.1016/j.exger.2014.03.030. Epub 2014 Apr 18.

PMID:
24747059
14.

Age versus nutritional state in the development of central leptin resistance.

Pétervári E, Rostás I, Soós S, Tenk J, Mikó A, Füredi N, Székely M, Balaskó M.

Peptides. 2014 Jun;56:59-67. doi: 10.1016/j.peptides.2014.03.011. Epub 2014 Mar 25.

PMID:
24680735
15.

The fine line between lifespan extension and shortening in response to caloric restriction.

Szafranski K, Mekhail K.

Nucleus. 2014 Jan-Feb;5(1):56-65. doi: 10.4161/nucl.27929. Epub 2014 Jan 27. Review.

16.

Changes in adipose tissue macrophages and T cells during aging.

Garg SK, Delaney C, Shi H, Yung R.

Crit Rev Immunol. 2014;34(1):1-14. Review.

17.

Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.

Cai W, Uribarri J, Zhu L, Chen X, Swamy S, Zhao Z, Grosjean F, Simonaro C, Kuchel GA, Schnaider-Beeri M, Woodward M, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4940-5. doi: 10.1073/pnas.1316013111. Epub 2014 Feb 24.

18.

Benefits of caloric restriction for cardiometabolic health, including type 2 diabetes mellitus risk.

Soare A, Weiss EP, Pozzilli P.

Diabetes Metab Res Rev. 2014 Mar;30 Suppl 1:41-7. doi: 10.1002/dmrr.2517. Review.

PMID:
24532291
19.

Perturbation of hypothalamic microRNA expression patterns in male rats after metabolic distress: impact of obesity and conditions of negative energy balance.

Sangiao-Alvarellos S, Pena-Bello L, Manfredi-Lozano M, Tena-Sempere M, Cordido F.

Endocrinology. 2014 May;155(5):1838-50. doi: 10.1210/en.2013-1770. Epub 2014 Feb 11.

PMID:
24517225
20.

Ideal body condition improves reproductive performance and influences genetic health in female mink.

Boudreau L, Benkel B, Astatkie T, Rouvinen-Watt K.

Anim Reprod Sci. 2014 Feb;145(1-2):86-98. doi: 10.1016/j.anireprosci.2014.01.004. Epub 2014 Jan 17.

PMID:
24486009
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