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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 3
1991 3
1992 4
1993 1
1994 3
1995 2
1996 2
1997 1
1998 5
1999 5
2000 4
2001 3
2002 3
2004 4
2005 4
2006 3
2007 3
2008 3
2009 3
2011 2
2012 2
2013 7
2014 9
2015 7
2016 3
2017 3
2018 5
2019 4
2020 6
2021 5
2022 5
2023 3
2024 3

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113 results

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Page 1
Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression.
Chan B, Glogauer M, Wang Y, Wrana J, Chan K, Beier F, Bali S, Hinz B, Parreno J, Ashraf S, Kandel R. Chan B, et al. Sci Adv. 2023 Aug 4;9(31):eadf1130. doi: 10.1126/sciadv.adf1130. Epub 2023 Aug 4. Sci Adv. 2023. PMID: 37540756 Free PMC article.
Together, these changes predisposed the articular cartilage to enhanced OA severity in Adseverin(-/-) mice who underwent surgical induction of OA. Adseverin(-/-) chondrocyte RNA sequencing and in vitro studies together suggests that adseverin modulates cell v …
Together, these changes predisposed the articular cartilage to enhanced OA severity in Adseverin(-/-) mice who underwent surgical ind …
Adseverin, an actin binding protein, regulates articular chondrocyte phenotype.
Chan B, Parreno J, Glogauer M, Wang Y, Kandel R. Chan B, et al. J Tissue Eng Regen Med. 2019 Aug;13(8):1438-1452. doi: 10.1002/term.2898. Epub 2019 Jun 14. J Tissue Eng Regen Med. 2019. PMID: 31090208
Given the changes in actin status with dedifferentiation, the hypothesis of this study was that adseverin, an actin severing and capping protein, plays a role in regulating chondrocyte phenotype and function. ...These are all features of dedifferentiation. These effects we …
Given the changes in actin status with dedifferentiation, the hypothesis of this study was that adseverin, an actin severing and capp …
The actin-binding protein Adseverin mediates neutrophil polarization and migration.
Glogauer J, Sun C, Wang Y, Glogauer M. Glogauer J, et al. Cytoskeleton (Hoboken). 2021 May;78(5):206-213. doi: 10.1002/cm.21684. Epub 2021 Aug 11. Cytoskeleton (Hoboken). 2021. PMID: 34370397
Using an Adseverin knockout mouse model, we show that Adseverin plays a role in subcortical F-actin assembly at the leading edge during chemotaxis through the generation of free barbed ends on existing actin filaments. In addition, in the absence of Adseverin …
Using an Adseverin knockout mouse model, we show that Adseverin plays a role in subcortical F-actin assembly at the leading ed …
Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1.
Song MK, Lee ZH, Kim HH. Song MK, et al. Exp Mol Med. 2015 Dec 18;47(12):e199. doi: 10.1038/emm.2015.94. Exp Mol Med. 2015. PMID: 26642432 Free PMC article.
However, the role of adseverin in bone cells has not yet been well characterized. Here, we investigated the role of adseverin in osteoclastogenesis using primary osteoclast precursor cells. ...Moreover, genetic silencing of adseverin decreased the number of o …
However, the role of adseverin in bone cells has not yet been well characterized. Here, we investigated the role of adseverin …
Adseverin modulates morphology and invasive function of MCF7 cells.
Tanic J, Wang Y, Lee W, Coelho NM, Glogauer M, McCulloch CA. Tanic J, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2716-2725. doi: 10.1016/j.bbadis.2019.07.015. Epub 2019 Jul 29. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31369818 Free article.
Adseverin (Ads) is a Ca(2+)-dependent actin-capping and severing protein that is highly expressed in gastric, prostate and bladder cancer cells. ...
Adseverin (Ads) is a Ca(2+)-dependent actin-capping and severing protein that is highly expressed in gastric, prostate and bladder ca …
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation.
Zhang J, Yu Q, Jiang D, Yu K, Yu W, Chi Z, Chen S, Li M, Yang D, Wang Z, Xu T, Guo X, Zhang K, Fang H, Ye Q, He Y, Zhang X, Wang D. Zhang J, et al. Sci Immunol. 2022 Feb 4;7(68):eabk2092. doi: 10.1126/sciimmunol.abk2092. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 35119941
Mechanistically, stimulation of goblet cells activates caspases to process GSDMD via reactive oxygen species production; in turn, this activated GSDMD drives mucin secretion through calcium ion-dependent scinderin-mediated cortical F-actin disassembly, which is a key step …
Mechanistically, stimulation of goblet cells activates caspases to process GSDMD via reactive oxygen species production; in turn, this activ …
Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.
Cao Y, Wang Y, Sprangers S, Picavet DI, Glogauer M, McCulloch CA, Everts V. Cao Y, et al. Calcif Tissue Int. 2017 Aug;101(2):207-216. doi: 10.1007/s00223-017-0271-6. Epub 2017 Apr 7. Calcif Tissue Int. 2017. PMID: 28389691 Free PMC article.
We analyzed bone and osteoclast structure in adseverin conditional null mice at alveolar and long bone sites. In wild-type and adseverin null mice, as measured by dual-energy X-ray absorptiometry, there were no differences of bone mineral content or bone mineral den …
We analyzed bone and osteoclast structure in adseverin conditional null mice at alveolar and long bone sites. In wild-type and ads …
IL1beta and TNFalpha promote RANKL-dependent adseverin expression and osteoclastogenesis.
Wang Y, Galli M, Shade Silver A, Lee W, Song Y, Mei Y, Bachus C, Glogauer M, McCulloch CA. Wang Y, et al. J Cell Sci. 2018 Jun 5;131(11):jcs213967. doi: 10.1242/jcs.213967. J Cell Sci. 2018. PMID: 29724913
In precursor cells, adseverin overexpression boosted the formation of RANKL-induced multinucleated cells. ...However, IL1beta and TNFalpha did not enhance osteoclast formation in adseverin-knockdown cells. RANKL-dependent adseverin expression in bone marrow c …
In precursor cells, adseverin overexpression boosted the formation of RANKL-induced multinucleated cells. ...However, IL1beta and TNF …
Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells.
Qi W, Gao Y, Tian J, Jiang H. Qi W, et al. Int J Mol Med. 2014 Dec;34(6):1483-91. doi: 10.3892/ijmm.2014.1941. Epub 2014 Sep 22. Int J Mol Med. 2014. PMID: 25339151 Free PMC article. Retracted.
Osteoclastogenesis is a complex process that is highly dependent on the dynamic regulation of the actin cytoskeleton. Adseverin (Ads), a member of the gelsolin superfamily of actin-binding proteins, regulates actin remodeling by severing and capping actin filaments. ...
Osteoclastogenesis is a complex process that is highly dependent on the dynamic regulation of the actin cytoskeleton. Adseverin (Ads) …
Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.
Jiang H, Wang Y, Viniegra A, Sima C, McCulloch CA, Glogauer M. Jiang H, et al. FASEB J. 2015 Jun;29(6):2281-91. doi: 10.1096/fj.14-265744. Epub 2015 Feb 13. FASEB J. 2015. PMID: 25681458
Osteoclast differentiation and function are highly dependent on the assembly and turnover of actin filaments, but little is known about the roles of actin binding proteins in these processes. Adseverin (Ads), a member of the gelsolin superfamily of actin capping and severi …
Osteoclast differentiation and function are highly dependent on the assembly and turnover of actin filaments, but little is known about the …
113 results