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Showing results for adars【纺】
Search for adarsa【纺】 instead (2 results)
Deciphering miRNAs' Action through miRNA Editing.
Correia de Sousa M, Gjorgjieva M, Dolicka D, Sobolewski C, Foti M. Correia de Sousa M, et al. Int J Mol Sci. 2019 Dec 11;20(24):6249. doi: 10.3390/ijms20246249. Int J Mol Sci. 2019. PMID: 31835747 Free PMC article. Review.
ADAR1 and its implications in cancer development and treatment.
Baker AR, Slack FJ. Baker AR, et al. Trends Genet. 2022 Aug;38(8):821-830. doi: 10.1016/j.tig.2022.03.013. Epub 2022 Apr 19. Trends Genet. 2022. PMID: 35459560 Free PMC article. Review.
The family of adenosine deaminases acting on RNA (ADARs) regulates global gene expression output by catalyzing adenosine-to-inosine (A-to-I) editing of double-stranded RNA (dsRNA) and through interacting with RNA and other proteins. ADARs play important roles in dev …
The family of adenosine deaminases acting on RNA (ADARs) regulates global gene expression output by catalyzing adenosine-to-inosine ( …
A-to-I editing of coding and non-coding RNAs by ADARs.
Nishikura K. Nishikura K. Nat Rev Mol Cell Biol. 2016 Feb;17(2):83-96. doi: 10.1038/nrm.2015.4. Epub 2015 Dec 9. Nat Rev Mol Cell Biol. 2016. PMID: 26648264 Free PMC article. Review.
Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA. This A-to-I editing occurs not only in protein-coding regions of mRNAs, but also frequently in non-coding regions that contain inverted Alu repeats. ...
Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA. This A-to-I editing occurs not only i …
Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides.
Merkle T, Merz S, Reautschnig P, Blaha A, Li Q, Vogel P, Wettengel J, Li JB, Stafforst T. Merkle T, et al. Nat Biotechnol. 2019 Feb;37(2):133-138. doi: 10.1038/s41587-019-0013-6. Epub 2019 Jan 28. Nat Biotechnol. 2019. PMID: 30692694
Here we describe the engineering of chemically optimized antisense oligonucleotides that recruit endogenous human ADARs to edit endogenous transcripts in a simple and programmable way, an approach we call RESTORE (recruiting endogenous ADAR to specific transcripts for olig …
Here we describe the engineering of chemically optimized antisense oligonucleotides that recruit endogenous human ADARs to edit endog …
ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels.
Hao X, Shiromoto Y, Sakurai M, Towers M, Zhang Q, Wu S, Havas A, Wang L, Berger S, Adams PD, Tian B, Nishikura K, Kossenkov AV, Liu P, Zhang R. Hao X, et al. Nat Cell Biol. 2022 Aug;24(8):1202-1210. doi: 10.1038/s41556-022-00959-z. Epub 2022 Jul 18. Nat Cell Biol. 2022. PMID: 35851616 Free PMC article.
Cellular senescence plays a causal role in ageing and, in mice, depletion of p16(INK4a)-expressing senescent cells delays ageing-associated disorders(1,2). Adenosine deaminases acting on RNA (ADARs) are RNA-editing enzymes that are also implicated as important regulators o …
Cellular senescence plays a causal role in ageing and, in mice, depletion of p16(INK4a)-expressing senescent cells delays ageing-associated …
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Rice GI, Kasher PR, Forte GM, Mannion NM, Greenwood SM, Szynkiewicz M, Dickerson JE, Bhaskar SS, Zampini M, Briggs TA, Jenkinson EM, Bacino CA, Battini R, Bertini E, Brogan PA, Brueton LA, Carpanelli M, De Laet C, de Lonlay P, del Toro M, Desguerre I, Fazzi E, Garcia-Cazorla A, Heiberg A, Kawaguchi M, Kumar R, Lin JP, Lourenco CM, Male AM, Marques W Jr, Mignot C, Olivieri I, Orcesi S, Prabhakar P, Rasmussen M, Robinson RA, Rozenberg F, Schmidt JL, Steindl K, Tan TY, van der Merwe WG, Vanderver A, Vassallo G, Wakeling EL, Wassmer E, Whittaker E, Livingston JH, Lebon P, Suzuki T, McLaughlin PJ, Keegan LP, O'Connell MA, Lovell SC, Crow YJ. Rice GI, et al. Nat Genet. 2012 Nov;44(11):1243-8. doi: 10.1038/ng.2414. Epub 2012 Sep 23. Nat Genet. 2012. PMID: 23001123 Free PMC article.
Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) and thereby potentially alter the information content and structure of cellular RNAs. ...
Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) …
A rADAR defense against RNAi.
Pasquinelli AE. Pasquinelli AE. Genes Dev. 2018 Feb 1;32(3-4):199-201. doi: 10.1101/gad.313049.118. Genes Dev. 2018. PMID: 29491134 Free PMC article. Review.
Adenosine deaminases that act on RNA (ADARs) convert adenosines (A) to inosines (I) in stretches of dsRNA. ...
Adenosine deaminases that act on RNA (ADARs) convert adenosines (A) to inosines (I) in stretches of dsRNA. ...
Host-mediated RNA editing in viruses.
Zhu T, Niu G, Zhang Y, Chen M, Li CY, Hao L, Zhang Z. Zhu T, et al. Biol Direct. 2023 Mar 28;18(1):12. doi: 10.1186/s13062-023-00366-w. Biol Direct. 2023. PMID: 36978112 Free PMC article. Review.
Here we synthesize the current knowledge of host-mediated RNA editing in a variety of viruses by considering two enzyme families, viz., ADARs and APOBECs, thereby presenting a landscape of diverse editing mechanisms and effects between viruses and hosts. ...
Here we synthesize the current knowledge of host-mediated RNA editing in a variety of viruses by considering two enzyme families, viz., A …
Mapping the dsRNA World.
Reich DP, Bass BL. Reich DP, et al. Cold Spring Harb Perspect Biol. 2019 Mar 1;11(3):a035352. doi: 10.1101/cshperspect.a035352. Cold Spring Harb Perspect Biol. 2019. PMID: 30824577 Free PMC article. Review.
Functions of long, cellular dsRNAs are poorly understood, although deficiencies in adenosine deaminases that act on RNA, or ADARs, promote their recognition as viral dsRNA and an aberrant immune response. ...
Functions of long, cellular dsRNAs are poorly understood, although deficiencies in adenosine deaminases that act on RNA, or ADARs, pr …
397 results