Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1971 1
1974 1
1975 1
1980 1
1982 3
1984 3
1986 2
1989 1
1990 2
1991 2
1992 3
1995 1
1998 3
1999 1
2000 1
2001 2
2002 1
2004 1
2005 4
2006 2
2008 1
2009 1
2010 4
2011 3
2012 2
2013 1
2014 1
2015 2
2016 2
2017 3
2018 1
2019 1
2020 4
2021 5
2022 2
2023 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

69 results

Results by year

Filters applied: . Clear all
Page 1
Renewable Reagent for Nucleophilic Fluorination.
Alič B, Petrovčič J, Jelen J, Tavčar G, Iskra J. Alič B, et al. J Org Chem. 2022 May 6;87(9):5987-5993. doi: 10.1021/acs.joc.2c00247. Epub 2022 Apr 19. J Org Chem. 2022. PMID: 35438994 Free PMC article.
The scope of substrates includes benzyl bromides, iodides, chlorides, aliphatic halides, tosylates, mesylates, alpha-haloketones, a silyl chloride, acyl and sulfuryl chlorides, and a nitroarene. ...
The scope of substrates includes benzyl bromides, iodides, chlorides, aliphatic halides, tosylates, mesylates, alpha-haloketones, a s …
A Short and Efficient Synthesis of Iminosugar 2-Acyl Indolizidine.
Chinthapally K, Karthik R, Senthilkumar S, Baskaran S. Chinthapally K, et al. Chemistry. 2017 Jan 12;23(3):533-536. doi: 10.1002/chem.201604376. Epub 2016 Nov 18. Chemistry. 2017. PMID: 27805289
A facile and convergent approach has been developed for the stereoselective construction of biologically important polyhydroxylated 2-acyl indolizidine framework using aza-Cope rearrangement-Mannich cyclization as a key step. The generality of this methodology is demonstra …
A facile and convergent approach has been developed for the stereoselective construction of biologically important polyhydroxylated 2-acy …
Diastereoselective synthesis of conformationally restricted KOR agonists.
Ilari D, Maskri S, Schepmann D, Köhler J, Daniliuc CG, Koch O, Wünsch B. Ilari D, et al. Org Biomol Chem. 2021 May 12;19(18):4082-4099. doi: 10.1039/d1ob00398d. Org Biomol Chem. 2021. PMID: 33978027
The three-step introduction of the pharmacophoric pyrrolidine ring started with nucleophilic substitution of exo-configured tosylate 26 with NaN3, which unexpectedly occurred under retention of configuration leading to exo-configured azide 31. The final KOR agonists 35 and …
The three-step introduction of the pharmacophoric pyrrolidine ring started with nucleophilic substitution of exo-configured tosylate …
Synthesis and Aldose Reductase Inhibition Effects of Novel N-Benzyl-4-Methoxyaniline Derivatives.
Bayrak C, Yildizhan G, Kilinc N, Durdagi S, Menzek A. Bayrak C, et al. Chem Biodivers. 2022 Jan;19(1):e202100530. doi: 10.1002/cbdv.202100530. Epub 2021 Dec 29. Chem Biodivers. 2022. PMID: 34889038
Corresponding N-benzylanilines and their derivatives were obtained from reductions (by NaBH(4) ) and substitutions (by acyl and tosyl chlorides) of these bases, respectively. The inhibitory effects of the sixteen compounds, twelve of which were novel compounds are e …
Corresponding N-benzylanilines and their derivatives were obtained from reductions (by NaBH(4) ) and substitutions (by acyl and to …
Ligand-directed acyl imidazole chemistry for labeling of membrane-bound proteins on live cells.
Fujishima SH, Yasui R, Miki T, Ojida A, Hamachi I. Fujishima SH, et al. J Am Chem Soc. 2012 Mar 7;134(9):3961-4. doi: 10.1021/ja2108855. Epub 2012 Feb 24. J Am Chem Soc. 2012. PMID: 22352855
A moderately reactive alkyloxyacyl imidazole (AI) assisted by ligand-binding affinity (ligand-directed AI (LDAI)) chemistry allowed us to selectively modify natural proteins, such as dihydrofolate reductase (DHFR) and folate receptor (FR), neither of which could be efficiently la …
A moderately reactive alkyloxyacyl imidazole (AI) assisted by ligand-binding affinity (ligand-directed AI (LDAI)) chemistry allowed us to se …
Rhodium-Catalyzed Selective Nucleophilic Cyclization/Cross-Coupling of Two ortho-Alkynylanilines Bearing Differential N-Substituents.
Li JC, Yan BX, Wang G, Ye ZS. Li JC, et al. Org Lett. 2023 Aug 11;25(31):5890-5895. doi: 10.1021/acs.orglett.3c02180. Epub 2023 Aug 2. Org Lett. 2023. PMID: 37530173
Herein, we reported an effective selective nucleophilic cyclization/cross-coupling cascade reaction of N-tosyl ortho-alkynylanilines and N-acyl ortho-alkynylanilines using Rh(COD)(2)BF(4)/(t)BuXantPhos as a catalyst. ...
Herein, we reported an effective selective nucleophilic cyclization/cross-coupling cascade reaction of N-tosyl ortho-alkynylanilines …
Hydrolysis of the GlcNAc oxazoline: deamidation and acyl rearrangement.
Jha R, Davis JT. Jha R, et al. Carbohydr Res. 1995 Nov 7;277(1):125-34. doi: 10.1016/0008-6215(95)00222-f. Carbohydr Res. 1995. PMID: 8548785
This two-step procedure provides an amino sugar which may be readily acylated to give novel glycoconjugates. Alternatively, base-catalyzed O-1-->N-2 acyl rearrangement of the amino tosylate 5d gives the 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranose 4 as …
This two-step procedure provides an amino sugar which may be readily acylated to give novel glycoconjugates. Alternatively, base-catalyzed O …
Dehydroepiandrosterone fatty acyl esters in high density lipoprotein: interaction with human vascular endothelial cells and vascular responses ex vivo.
Paatela H, Vihma V, Jauhiainen M, Mervaala E, Tikkanen MJ. Paatela H, et al. Steroids. 2011 Mar;76(4):376-80. doi: 10.1016/j.steroids.2010.12.007. Epub 2010 Dec 17. Steroids. 2011. PMID: 21168430
Dehydroepiandrosterone (DHEA) fatty acyl esters once incorporated in high density lipoprotein (HDL) induce a stronger vasodilatory response in rat mesenteric arteries ex vivo compared to native HDL. We studied the role of HDL receptor, scavenger receptor class B, type 1 (S …
Dehydroepiandrosterone (DHEA) fatty acyl esters once incorporated in high density lipoprotein (HDL) induce a stronger vasodilatory re …
Nickel/Photo-Cocatalyzed Regioselective Ring Opening of N-Tosyl Styrenyl Aziridines with Aldehydes.
Fan P, Jin Y, Liu J, Wang R, Wang C. Fan P, et al. Org Lett. 2021 Oct 1;23(19):7364-7369. doi: 10.1021/acs.orglett.1c02514. Epub 2021 Sep 20. Org Lett. 2021. PMID: 34543571
In this protocol, the merger of nickel and hydrogen-atom-transfer photocatalysis successfully enables the ring opening of N-tosyl styrenyl aziridines with aldehydes, providing a novel and atom-economical access to a variety of beta-amino ketones with complete regiocontrol. …
In this protocol, the merger of nickel and hydrogen-atom-transfer photocatalysis successfully enables the ring opening of N-tosyl sty …
69 results