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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1901 1
1908 1
1909 3
1910 1
1911 4
1912 2
1913 2
1914 2
1915 4
1917 3
1919 2
1920 5
1921 2
1922 3
1923 5
1924 3
1925 4
1926 3
1927 3
1928 5
1929 4
1930 1
1931 3
1932 5
1933 5
1934 5
1935 2
1936 3
1937 7
1938 8
1939 2
1940 2
1941 7
1942 5
1943 6
1944 7
1945 13
1946 14
1947 15
1948 25
1949 21
1950 13
1951 20
1952 19
1953 29
1954 33
1955 34
1956 35
1957 59
1958 40
1959 64
1960 51
1961 88
1962 105
1963 90
1964 130
1965 160
1966 179
1967 258
1968 269
1969 342
1970 383
1971 437
1972 541
1973 593
1974 632
1975 2345
1976 2613
1977 2324
1978 2284
1979 2601
1980 3023
1981 3236
1982 3711
1983 4619
1984 5093
1985 5607
1986 5974
1987 6417
1988 6880
1989 7929
1990 8699
1991 9415
1992 9997
1993 10637
1994 11235
1995 12485
1996 13836
1997 14560
1998 15762
1999 17009
2000 18678
2001 19903
2002 21448
2003 23077
2004 25453
2005 27781
2006 29882
2007 31952
2008 33399
2009 35236
2010 38419
2011 40993
2012 44511
2013 47465
2014 49438
2015 51466
2016 52765
2017 55561
2018 58655
2019 62493
2020 69546
2021 75911
2022 77426
2023 75548
2024 38181
2025 13

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1,174,298 results

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Page 1
Exercise training improves motor skill learning via selective activation of mTOR.
Chen K, Zheng Y, Wei JA, Ouyang H, Huang X, Zhang F, Lai CSW, Ren C, So KF, Zhang L. Chen K, et al. Sci Adv. 2019 Jul 3;5(7):eaaw1888. doi: 10.1126/sciadv.aaw1888. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281888 Free PMC article.
Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. Here, we show that chronic treadmill exercise activates the mechanistic target of rapamycin (mTOR) pathway in mouse motor cor …
Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. …
Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise.
Shimomura Y, Murakami T, Nakai N, Nagasaki M, Harris RA. Shimomura Y, et al. J Nutr. 2004 Jun;134(6 Suppl):1583S-1587S. doi: 10.1093/jn/134.6.1583S. J Nutr. 2004. PMID: 15173434 Free article. Review.
It is known that BCAA oxidation is promoted by exercise. The mechanism responsible for this phenomenon is attributed to activation of the branched-chain alpha-keto acid dehydrogenase (BCKDH) complex, which catalyzes the second-step reaction of the BCAA catabolic pat …
It is known that BCAA oxidation is promoted by exercise. The mechanism responsible for this phenomenon is attributed to activation …
Muscle fatigue: what, why and how it influences muscle function.
Enoka RM, Duchateau J. Enoka RM, et al. J Physiol. 2008 Jan 1;586(1):11-23. doi: 10.1113/jphysiol.2007.139477. Epub 2007 Aug 16. J Physiol. 2008. PMID: 17702815 Free PMC article. Review.
Much is known about the physiological impairments that can cause muscle fatigue. It is known that fatigue can be caused by many different mechanisms, ranging from the accumulation of metabolites within muscle fibres to the generation of an inadequate motor command i …
Much is known about the physiological impairments that can cause muscle fatigue. It is known that fatigue can be caused by many different …
Sedentarism, active lifestyle and sport: Impact on health and obesity prevention.
González-Gross M, Meléndez A. González-Gross M, et al. Nutr Hosp. 2013 Sep;28 Suppl 5:89-98. doi: 10.3305/nh.2013.28.sup5.6923. Nutr Hosp. 2013. PMID: 24010748 Free article. Review.
Metabolic fat oxidation rate is highest at exercise intensities between 45 and 65% of VO2max. This means that people must be active regularly and force physiological mechanisms at certain intensities. All this body of evidence has contributed to current WHO physical …
Metabolic fat oxidation rate is highest at exercise intensities between 45 and 65% of VO2max. This means that people must be active r …
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Lagouge M, et al. Cell. 2006 Dec 15;127(6):1109-22. doi: 10.1016/j.cell.2006.11.013. Epub 2006 Nov 16. Cell. 2006. PMID: 17112576 Free article.
RSV's effects were associated with an induction of genes for oxidative phosphorylation and mitochondrial biogenesis and were largely explained by an RSV-mediated decrease in PGC-1alpha acetylation and an increase in PGC-1alpha activity. This mechanism is consistent …
RSV's effects were associated with an induction of genes for oxidative phosphorylation and mitochondrial biogenesis and were largely explain …
Energy Constraint as a Novel Mechanism Linking Exercise and Health.
Pontzer H. Pontzer H. Physiology (Bethesda). 2018 Nov 1;33(6):384-393. doi: 10.1152/physiol.00027.2018. Physiology (Bethesda). 2018. PMID: 30303776 Free article. Review.
Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This e …
Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narro …
Mechanism for activation of locomotor centers in the spinal cord by stimulation of the mesencephalic locomotor region.
Noga BR, Kriellaars DJ, Brownstone RM, Jordan LM. Noga BR, et al. J Neurophysiol. 2003 Sep;90(3):1464-78. doi: 10.1152/jn.00034.2003. Epub 2003 Mar 12. J Neurophysiol. 2003. PMID: 12634275 Free article.
Bilateral cooling of the MedRF reversibly abolished locomotion of both hindlimbs as measured from the electroneurogram (ENG) activity of muscle nerves and simultaneously abolished or diminished the motoneuron PSPs and LDPs. ...Local segmental pathways that activate …
Bilateral cooling of the MedRF reversibly abolished locomotion of both hindlimbs as measured from the electroneurogram (ENG) activity …
Atlas of exercise-induced brain activation in mice.
Skovbjerg G, Fritzen AM, Svendsen CSA, Perens J, Skytte JL, Lund C, Lund J, Madsen MR, Roostalu U, Hecksher-Sørensen J, Clemmensen C. Skovbjerg G, et al. Mol Metab. 2024 Apr;82:101907. doi: 10.1016/j.molmet.2024.101907. Epub 2024 Feb 28. Mol Metab. 2024. PMID: 38428817 Free PMC article.
In this study, we utilize forced treadmill running and distance-matched voluntary wheel running, coupled with light sheet 3D brain imaging and c-Fos immunohistochemistry, to generate a comprehensive atlas of exercise-induced brain activation in mice. METHODS: To investigat …
In this study, we utilize forced treadmill running and distance-matched voluntary wheel running, coupled with light sheet 3D brain imaging a …
Around LTD hypothesis in motor learning.
Hirano T. Hirano T. Cerebellum. 2014 Oct;13(5):645-50. doi: 10.1007/s12311-014-0581-4. Cerebellum. 2014. PMID: 24974094 Free article. Review.
Long-term depression (LTD) at parallel fiber-Purkinje neuron synapses has been regarded as a primary cellular mechanism for motor learning. However, this hypothesis has been challenged. Demonstration of normal motor learning under LTD-suppressed conditions su …
Long-term depression (LTD) at parallel fiber-Purkinje neuron synapses has been regarded as a primary cellular mechanism for motor …
Amphetamine activation of hippocampal drive of mesolimbic dopamine neurons: a mechanism of behavioral sensitization.
Lodge DJ, Grace AA. Lodge DJ, et al. J Neurosci. 2008 Jul 30;28(31):7876-82. doi: 10.1523/JNEUROSCI.1582-08.2008. J Neurosci. 2008. PMID: 18667619 Free PMC article.
Using in vivo extracellular recordings from identified ventral tegmental area dopamine (DA) neurons, we report that amphetamine-sensitized rats display an activation of ventral hippocampal neuron firing and a significantly greater number of spontaneously active DA n …
Using in vivo extracellular recordings from identified ventral tegmental area dopamine (DA) neurons, we report that amphetamine-sensitized r …
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