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Results: 1 to 20 of 63

1.

Novel mechanisms of endothelial mechanotransduction.

Abe J, Berk BC.

Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2378-86. doi: 10.1161/ATVBAHA.114.303428. Epub 2014 Oct 9.

PMID:
25301843
[PubMed - in process]
2.

Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents.

Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe J.

J Immunol. 2014 Oct 1;193(7):3803-15. doi: 10.4049/jimmunol.1400571. Epub 2014 Sep 3.

PMID:
25187658
[PubMed - in process]
3.

ERK5 activation in macrophages promotes efferocytosis and inhibits atherosclerosis.

Heo KS, Cushman HJ, Akaike M, Woo CH, Wang X, Qiu X, Fujiwara K, Abe J.

Circulation. 2014 Jul 8;130(2):180-91. doi: 10.1161/CIRCULATIONAHA.113.005991. Epub 2014 Apr 28.

PMID:
25001623
[PubMed - indexed for MEDLINE]
4.

Shear stress and atherosclerosis.

Heo KS, Fujiwara K, Abe J.

Mol Cells. 2014 Jun;37(6):435-40. doi: 10.14348/molcells.2014.0078. Epub 2014 Apr 30.

PMID:
24781409
[PubMed - in process]
Free PMC Article
5.

Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury.

Oikawa M, Wu M, Lim S, Knight WE, Miller CL, Cai Y, Lu Y, Blaxall BC, Takeishi Y, Abe J, Yan C.

J Mol Cell Cardiol. 2013 Nov;64:11-9. doi: 10.1016/j.yjmcc.2013.08.003. Epub 2013 Aug 27.

PMID:
23988739
[PubMed - indexed for MEDLINE]
6.

Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation, and Biomarkers in Cardiovascular Inflammation.

Abe J, Manabe I, Aikawa M, Aikawa E.

Int J Inflam. 2013;2013:953463. doi: 10.1155/2013/953463. Epub 2013 Mar 10. No abstract available.

PMID:
23555068
[PubMed]
Free PMC Article
7.

De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.

Heo KS, Chang E, Le NT, Cushman H, Yeh ET, Fujiwara K, Abe J.

Circ Res. 2013 Mar 15;112(6):911-23. doi: 10.1161/CIRCRESAHA.111.300179. Epub 2013 Feb 4.

PMID:
23381569
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.

Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29.

PMID:
23202365
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells.

Kim GY, Nigro P, Fujiwara K, Abe J, Berk BC.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2974-80. doi: 10.1161/ATVBAHA.112.300054. Epub 2012 Sep 27.

PMID:
23023376
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation.

Le NT, Corsetti JP, Dehoff-Sparks JL, Sparks CE, Fujiwara K, Abe J.

Int J Inflam. 2012;2012:678190. Epub 2012 Sep 6.

PMID:
22991685
[PubMed]
Free PMC Article
11.

Glucagon-like peptide-1 and its cardiovascular effects.

Heo KS, Fujiwara K, Abe J.

Curr Atheroscler Rep. 2012 Oct;14(5):422-8. doi: 10.1007/s11883-012-0265-9. Review.

PMID:
22878937
[PubMed - indexed for MEDLINE]
12.

p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.

Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J.

Circ Res. 2012 Feb 17;110(4):536-50. doi: 10.1161/CIRCRESAHA.111.254730. Epub 2012 Jan 19.

PMID:
22267842
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction.

Heo KS, Fujiwara K, Abe J.

Circ J. 2011;75(12):2722-30. Epub 2011 Nov 10. Review.

PMID:
22076424
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation.

Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J.

J Cell Biol. 2011 May 30;193(5):867-84. doi: 10.1083/jcb.201010051.

PMID:
21624955
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury.

Shi X, Yan C, Nadtochiy SM, Abe J, Brookes PS, Berk BC.

J Mol Cell Cardiol. 2011 Aug;51(2):272-5. doi: 10.1016/j.yjmcc.2011.05.005. Epub 2011 May 14. Erratum in: J Mol Cell Cardiol. 2012 Jan;52(1):292.

PMID:
21609719
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice.

Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe J, Alexis JD, Sparks JD, Berk BC.

J Exp Med. 2011 Jan 17;208(1):53-66. doi: 10.1084/jem.20101174. Epub 2010 Dec 20.

PMID:
21173104
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation.

Chang E, Heo KS, Woo CH, Lee H, Le NT, Thomas TN, Fujiwara K, Abe J.

Blood. 2011 Feb 24;117(8):2527-37. doi: 10.1182/blood-2010-08-302281. Epub 2010 Dec 3.

PMID:
21131586
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells.

Jeon KI, Jono H, Miller CL, Cai Y, Lim S, Liu X, Gao P, Abe J, Li JD, Yan C.

FEBS J. 2010 Dec;277(24):5026-39. doi: 10.1111/j.1742-4658.2010.07908.x. Epub 2010 Nov 16.

PMID:
21078118
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Flow shear stress and atherosclerosis: a matter of site specificity.

Nigro P, Abe J, Berk BC.

Antioxid Redox Signal. 2011 Sep 1;15(5):1405-14. doi: 10.1089/ars.2010.3679. Epub 2011 Apr 8. Review.

PMID:
21050140
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

Woo CH, Le NT, Shishido T, Chang E, Lee H, Heo KS, Mickelsen DM, Lu Y, McClain C, Spangenberg T, Yan C, Molina CA, Yang J, Patterson C, Abe J.

FASEB J. 2010 Dec;24(12):4917-28. doi: 10.1096/fj.10-162636. Epub 2010 Aug 19.

PMID:
20724525
[PubMed - indexed for MEDLINE]
Free PMC Article

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